Photoinduced force microscopy as a novel method for the study of microbial nanostructures DOI Creative Commons
Josh A. Davies-Jones, Philip R. Davies,

Arthur Graf

и другие.

Nanoscale, Год журнала: 2023, Номер 16(1), С. 223 - 236

Опубликована: Ноя. 28, 2023

A detailed comparison of the capabilities electron microscopy and nano-infrared (IR) for imaging microbial nanostructures has been carried out first time. The surface sensitivity, chemical specificity, non-destructive nature spectroscopic mapping is shown to offer significant advantages over transmission (TEM) study biological samples. As well as yielding important topographical information, distribution amides, lipids, carbohydrates across cross-sections bacterial (Escherichia coli, Staphylococcus aureus) fungal (Candida albicans) cells was demonstrated using PiFM. unique information derived from this new mode chemistry biology cell walls membranes, may provide insights into fungal/bacterial function having potential use in determining mechanisms antimicrobial resistance, especially those targeting wall.

Язык: Английский

Assessment of modified chitosan composite in acidic reservoirs through pilot and field-scale simulation studies DOI Creative Commons

Hamid Khattab,

Ahmed A. Gawish, Sayed Gomaa

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Май 9, 2024

Abstract Chemical flooding through biopolymers acquires higher attention, especially in acidic reservoirs. This research focuses on the application of chemical for enhanced oil recovery reservoirs, with a particular emphasis modified chitosan. The modification process involved combining chitosan vinyl/silane monomers via emulsion polymerization, followed by an assessment its rheological behavior under simulated reservoir conditions, including salinity, temperature, pressure, and medium pH. Laboratory-scale experiments were carried out using both original at conditions 2200 psi, 135,000 ppm 196° temperature. study evaluated impact pressure properties forms, finding that composite was better suited to environments, showing resistance effects significant increase viscosity 11% improvement over 5% achieved unmodified Advanced modeling simulation techniques, particularly tNavigator Simulator Bahariya formations Western Desert, employed further understand polymer solution dynamics contexts predict key petroleum engineering metrics. results underscored effectiveness increasing rates, outperforming native counterpart traditional water flooding, achieving factor 48%, compared 39% 37% thereby demonstrating potential benefits composites enhancing operations.

Язык: Английский

Процитировано

25

Morphological and Biophysical Study of S100A9 Protein Fibrils by Atomic Force Microscopy Imaging and Nanomechanical Analysis DOI Creative Commons
Ana P. Carapeto, Carlos Marcuello, Patrícia F. N. Faísca

и другие.

Biomolecules, Год журнала: 2024, Номер 14(9), С. 1091 - 1091

Опубликована: Авг. 31, 2024

Atomic force microscopy (AFM) imaging enables the visualization of protein molecules with high resolution, providing insights into their shape, size, and surface topography. Here, we use AFM to study aggregation process S100A9 in physiological conditions, presence calcium at a molar ratio 4Ca2+:S100A9. We find that readily assembles worm-like fibril, period dimension along fibril axis 11.5 nm. The fibril’s chain length extends up 136 periods after an incubation time 144 h. At room temperature, bending stiffness was found be 2.95×10−28 Nm2, indicating fibrils are relatively flexible. Additionally, values obtained for Young’s modulus (Ex=6.96×105 Pa Ey=3.37×105 Pa) four orders magnitude lower than those typically reported canonical amyloid fibrils. Our findings suggest that, under investigated distinct mechanism may place calcium. Therefore, here could have implications field biomedicine, particularly regard Alzheimer’s disease.

Язык: Английский

Процитировано

16

Advancements in the application of surface roughness in mineral flotation process DOI
Cheng Gan,

Li Xiong,

Yang Lu

и другие.

Separation Science and Technology, Год журнала: 2024, Номер 59(4), С. 592 - 611

Опубликована: Март 3, 2024

The fundamental surface properties of different particles play an important role in the hydrophobicity and flotation performance minerals. In recent years, influence physical on flotability minerals has garnered significant attention, revealing a positive correlation between roughness performance. This paper analyzes effects mineral characteristics process. An in-depth review methods for measuring modifying to comprehensively analyze its is also included. include methods, chemical utilization nanoparticle collectors. Additionally, this explores molecular simulation, fast-approaching powerful tool investigating reagent-mineral interactions. Here, changes model their wettability simulation techniques discussed, facilitate application flotation.

Язык: Английский

Процитировано

10

Scanning probe microscopy elucidates gelation and rejuvenation of biomolecular condensates DOI Creative Commons
Aida Naghilou, Oskar Armbruster, Alireza Mashaghi

и другие.

Cell Reports Physical Science, Год журнала: 2025, Номер unknown, С. 102430 - 102430

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

1

Interaction forces between bitumen and clay minerals in oil sands liberation process at different solution environments DOI
Bobo Zhou,

Xinyi Zhao,

Xuesong Yang

и другие.

Physics of Fluids, Год журнала: 2025, Номер 37(3)

Опубликована: Март 1, 2025

Global oil sands resources are abundant, and their effective development can help alleviate the global petroleum shortage. However, fine clay minerals metal cations significantly reduce liberation efficiency of sands. To elucidate mechanisms behind difficulty in liberating bitumen, chemical structures, microscopic morphologies, elemental compositions bitumen were systematically characterized, using Fourier-transform infrared spectroscopy, contact angle, scanning electron microscopy, energy-dispersive x-ray diffraction methods. Additionally, atomic force microscopy colloidal probe technology was employed to investigate interaction forces between typical (silica, kaolinite, illite, montmorillonite) at different solution environments. The results showed that adhesion (≥14.3 nN) higher than (7.9 silica distilled water. Furthermore, presence increased both jump-out distances bitumen. Divalent cations, with charge, had a greater impact on monovalent cation due stronger electrostatic interactions negatively charged substrates. In particular, montmorillonite most affected by divalent distance reaching 44.6 nN 80 nm 10 mM CaCl2 solution. led surface coverage, reducing efficiency. These findings provide insights into underlying from sands, providing theoretical for efficient extraction sand ores industrial applications.

Язык: Английский

Процитировано

1

Synergistic effect and mechanism of ferric ion modified citric acid depressant in the flotation separation of scheelite from cassiterite DOI
Qifang Zheng, Liuyang Dong, Peilun Shen

и другие.

Separation and Purification Technology, Год журнала: 2024, Номер 353, С. 128423 - 128423

Опубликована: Июнь 14, 2024

Язык: Английский

Процитировано

6

An Approach to Monodisperse Polymeric Particles as Matrices for Immobilization of Biosystems DOI Creative Commons
Mariana Paola Cabrera,

GERALDO VIEIRA DE LIMA JÚNIOR,

William S. Soares

и другие.

Physchem, Год журнала: 2025, Номер 5(1), С. 2 - 2

Опубликована: Янв. 2, 2025

In this paper, the benefits of using monodisperse polymeric particles as matrices to immobilize biosystems are presented and discussed. The nature polymer (natural, synthetic, or semisynthetic) immobilization techniques were directly related performance process. addition, work reviews major biological synthetic entities that have been immobilized on their potential applications available in literature. research revealed enzymes, proteins, cells, drugs main matrices. Several physicochemical characterization discussed determine presence after some enzymes different areas also since biomolecule was most frequent entity terms Finally, review describes advances materials used supports for immobilizing due interesting physical chemical properties.

Язык: Английский

Процитировано

0

Guidance on biomaterials for periodontal tissue regeneration: Fabrication methods, materials and biological considerations DOI Creative Commons
Nicholas G. Fischer, Isaac Jordão de Souza Araújo, Arwa Daghrery

и другие.

Dental Materials, Год журнала: 2025, Номер 41(3), С. 283 - 305

Опубликована: Янв. 9, 2025

Regeneration of the multiple tissues and interfaces in periodontal complex necessitates multidisciplinary evaluation to establish structure/function relationships. This article, an initiative Academy Dental Materials, provides guidance for performing chemical, structural, mechanical characterization materials tissue regeneration, outlines important recommendations on methods testing bioactivity, biocompatibility, antimicrobial properties biomaterials/scaffolds engineering. First, we briefly summarize engineering fabrication methods. We then highlight critical variables consider when evaluating a material fundamental tests used investigate them. The recommended designs incorporate relevant international standards provide framework characterizing newly developed focusing applicability those regeneration. most common biofabrication (electrospinning, injectable hydrogels, fused deposition modelling, melt electrowriting, bioprinting) their specific applications are reviewed. techniques morphological, different classes regeneration described. major advantages drawbacks each assay, sample sizes, guidelines specimen preparation also highlighted. From biological standpoint, biocompatibility materials, experimental models potential included this guidance. In conclusion, researchers studies will have as tool assess essential characteristics materials/scaffold-based strategies.

Язык: Английский

Процитировано

0

Advances in Extracellular Matrix-Associated Diagnostics and Therapeutics DOI Open Access
M.A. Karsdal, Thomas R. Cox, Amelia L. Parker

и другие.

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(6), С. 1856 - 1856

Опубликована: Март 10, 2025

The extracellular matrix (ECM) is the common denominator of more than 50 chronic diseases. Some these pathologies lead to enhanced tissue formation and deposition, whereas others are associated with increased degradation, some exhibit a combination both, leading severe alterations. To develop effective therapies for diseases affecting lung, liver, kidney, skin, intestine, musculoskeletal system, heart, solid tumors, we need modulate ECM’s composition restore its organization function. Across diverse organ diseases, there denominators distinguishing factors in this fibroinflammatory axis, which may be used foster new insights into drug development across disease indications. 2nd Extracellular Matrix Pharmacology Congress took place Copenhagen, Denmark, from 17 19 June 2024 was hosted by International Society Pharmacology. event attended 450 participants 35 countries, among whom were prominent scientists who brought together state-of-the-art research on asked important questions facilitate development. We highlight key aspects ECM lungs, tumors advance our understanding central targets also advances tools technology that enable development, thereby supporting ECM.

Язык: Английский

Процитировано

0

Calibration of the lateral spring constant for a custom T-shaped atomic force microscopy probe DOI
Zhimu Yang, Rui Xu,

Dongchao Zhao

и другие.

Review of Scientific Instruments, Год журнала: 2025, Номер 96(3)

Опубликована: Март 1, 2025

Atomic force microscopy (AFM) is a versatile tool for investigating nanotribology, where the probe’s lateral spring constant critical parameter. This work introduced method to calibrate of T-shaped probe integrated into custom AFM system. An expression was derived by correlating bending and torsional resonance frequencies with its reduced masses moments inertia. In experiment, electrochemical etching utilized gradually reduce mass tip. The excited using three piezoelectric techniques, allowing measurement across different vibration modes. Finite element analysis performed predict constants probes varying dimensions, confirming reliability proposed method.

Язык: Английский

Процитировано

0