Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 40, С. 101341 - 101341
Опубликована: Сен. 25, 2024
Язык: Английский
Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 40, С. 101341 - 101341
Опубликована: Сен. 25, 2024
Язык: Английский
Journal of Industrial and Engineering Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1Scientific Reports, Год журнала: 2024, Номер 14(1)
Опубликована: Июль 29, 2024
Abstract Cerium oxide nanoparticles possess unique properties that make them promising candidates in various fields, including cancer treatment. Among the proposed synthesis methods for CNPs, biosynthesis using natural extracts, offers an eco-friendly and convenient approach producing particularly biomedical applications. In this study, a novel method of aqueous extract Eucalyptus camaldulensis leaves was used to synthesize CNPs. Scanning electron microscopy Transmission (TEM) techniques revealed synthesized CNPs exhibit flower-like morphology. The particle size obtained Powder X-ray diffraction peaks TEM as 13.43 39.25 nm. Energy-dispersive spectroscopy Fourier transform infrared confirmed effect biomolecules during process formation cytotoxicity biosynthesized samples evaluated MTT demonstrating potential these inhibit MCF-7 cancerous cells. viability cell line conducted by live/dead imaging assay indicated their Furthermore, successful uptake cells, demonstrated confocal microscopy, provides evidence intracellular pathway contributes anticancer activity general, results indicate significant against line, attributed high surface area.
Язык: Английский
Процитировано
8Ionics, Год журнала: 2024, Номер 30(9), С. 5737 - 5754
Опубликована: Июль 9, 2024
Язык: Английский
Процитировано
6International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 135656 - 135656
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
6Ionics, Год журнала: 2025, Номер unknown
Опубликована: Март 20, 2025
Язык: Английский
Процитировано
0ACS Applied Bio Materials, Год журнала: 2025, Номер unknown
Опубликована: Май 14, 2025
Microbial infections and colorectal cancer are significant contributors to mortality morbidity, necessitating prompt action. In the present work, NiTiO3 (NT), curcumin-loaded (CUNT), chitosan-loaded (CHNT), both curcumin (CUCHNT) hybrid nanomaterials (HNMs) were systematically prepared using Psidium guajava leaf extract. PXRD studies revealed that NT, CUNT, CHNT, CUCHNT exhibited a rhombohedral structure with R3̅ space group mean crystallite sizes of ∼66.41, ∼61.94, ∼61.65, ∼65.12 nm, respectively. Band gap energies estimated as ∼3.10, ∼3.15, ∼3.14, ∼3.15 eV for CUCHNT, Antibacterial efficacies synthesized HNMs analyzed against Gram-positive (G+) Gram-negative (G-) bacteria well diffusion method, zone inhibition (ZOI) by Staphylococcus aureus 11.5, 13, 12, 17.5 mm, respectively; those pneumoniae 9, 13.5, 11, 14 Klebsiella 10, 9.5, 17 Escherichia coli 16.5 ZOI results showed have superior antibacterial all tested bacterial strains compared CHNT. Cytotoxic capabilities MTT assay HCT-116 carcinoma cell line. All anticancer activity, exhibiting most pronounced having an IC50 value 87 μg/mL. Morphological changes death mechanisms studied dual AO/EtBr, H2DCFDA, JC-1 staining. These findings emphasize biosynthesized P. extract could be potential therapeutic agent antimicrobial applications.
Язык: Английский
Процитировано
0Chemical Papers, Год журнала: 2024, Номер 79(1), С. 193 - 209
Опубликована: Ноя. 19, 2024
Язык: Английский
Процитировано
3Materials Today Bio, Год журнала: 2024, Номер 30, С. 101377 - 101377
Опубликована: Дек. 5, 2024
We explored the feasibility of a self-assembled chitosan nanocomposite incorporating cerium oxide/nanoceria and superparamagnetic iron oxide nanoparticles (Chit-IOCO NPs), conjugated with methotrexate (MTX) Cy5 dye, as an integrated cancer theranostic nanosystem (Chit-IOCO-MTX-Cy5). In this system, nanoceria serves anti-cancer agent, while function negative contrast agent for MR imaging. This dual metal is MTX which structural analogue folate, serving both targeting mechanism folate receptors on cells chemotherapeutic drug. Chit-IOCO-MTX-Cy5 exhibited exceptional in T2 T2∗-weighted MRI, achieving high relaxivity 409.5 mM⁻
Язык: Английский
Процитировано
3Ionics, Год журнала: 2025, Номер unknown
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114798 - 114798
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
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