Опубликована: Янв. 1, 2025
Язык: Английский
Опубликована: Янв. 1, 2025
Язык: Английский
Journal of Alloys and Compounds, Год журнала: 2023, Номер 962, С. 171167 - 171167
Опубликована: Июнь 27, 2023
Язык: Английский
Процитировано
28The Science of The Total Environment, Год журнала: 2023, Номер 868, С. 161702 - 161702
Опубликована: Янв. 19, 2023
Язык: Английский
Процитировано
24Chemical Engineering Journal, Год журнала: 2024, Номер 495, С. 153651 - 153651
Опубликована: Июль 1, 2024
Язык: Английский
Процитировано
11Chemosphere, Год журнала: 2024, Номер 364, С. 143147 - 143147
Опубликована: Авг. 19, 2024
BPA and its analogues are facing increasingly stringent regulations restricting their use due to the increasing knowledge of harmful effects. It is therefore expected that novel alternatives will replace them in plastic products, cans thermal paper circumvent restrictions imposed by legislation. This raises concerns about safety "BPA-free" as they contain substitutes whose has not been sufficiently assessed prior market introduction. The regulatory agencies have recognised BPAP, BPBP, BPC2, BPE, BPFL, BPG, BPP, BPPH, BPS-MAE, BPS-MPE, BP-TMC, BPZ BTUM, D-90, UU PF201 compound with insufficient data regarding safety. We demonstrate mentioned compounds present consumer food environment, thus exhibiting toxicological risk only humans, but also other species where toxic effects already described. Results silico, vitro vivo studies examining endocrine disruption show disrupt system targeting various nuclear receptors, impairing reproductive function causing such hepatotoxicity, altered behaviour impaired function. In on literally non-existent, although these commonly used papers. However, silico predicted might cause adverse well. aim this article comprehensively collate information selected illustrate potential toxicity identify gaps.
Язык: Английский
Процитировано
11Ecotoxicology and Environmental Safety, Год журнала: 2023, Номер 260, С. 115098 - 115098
Опубликована: Июнь 1, 2023
As a result of the ban on bisphenol A (BPA), hormone disruptor with developmental neurotoxicity, several BPA derivatives (BPs) have been widely used in industrial production. However, there are no effective methods for assessing neurodevelopmental toxic effects BPs. To address this, Drosophila exposure model was established, and W1118 reared food containing these Results showed that each BPs displayed different semi-lethal doses ranging from 1.76 to 19.43 mM. Exposure delayed larval development affected axonal growth, resulting abnormal crossing midline axons β lobules mushroom bodies, but damage caused by BPE BPF relatively minor. BPC, BPAF, BPAP most significant locomotor behavior, whereas BPC exhibited social interactions. Furthermore, high-dose BPA, BPS, also significantly increased expression estrogen-related receptors. These demonstrated kinds had levels toxicity, severity BPZ > BPAF BPB BPS ≈ BPAl BPE. Therefore, BPZ, should be evaluated as potential alternatives BPA.
Язык: Английский
Процитировано
21Environment & Health, Год журнала: 2024, Номер 2(6), С. 373 - 380
Опубликована: Май 1, 2024
Bisphenol AP (BPAP) is a bisphenol analogue that used as substitute for BPA in industrial production and now commonly found the environment. Currently, there limited information available on its developmental toxicity aquatic organisms. This study exploited zebrafish embryos to investigate adverse effects of BPAP exposure during their early life stages. The results revealed had median lethal concentration (LC50) 36, 22, 8.5 μmol/L at 24, 48, 72 h post fertilization (hpf), respectively. Additionally, led abnormal development embryos, including hatching delay, malformation, inhibition spontaneous movements. Transcriptomic analysis further upregulated mRNA expression levels genes related inflammatory pathways, such il1b, ptgs2b, fosab, indicating induction an response. Overall, our findings provide valuable insights into environmental health risks associated with exposure.
Язык: Английский
Процитировано
9Environment International, Год журнала: 2024, Номер 193, С. 109105 - 109105
Опубликована: Окт. 30, 2024
Язык: Английский
Процитировано
9Separation and Purification Technology, Год журнала: 2024, Номер 342, С. 126968 - 126968
Опубликована: Март 2, 2024
Язык: Английский
Процитировано
8Food and Chemical Toxicology, Год журнала: 2024, Номер 188, С. 114652 - 114652
Опубликована: Апрель 6, 2024
Язык: Английский
Процитировано
7The Science of The Total Environment, Год журнала: 2022, Номер 839, С. 156221 - 156221
Опубликована: Май 24, 2022
Язык: Английский
Процитировано
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