Polystyrene-microplastics and DEHP co-exposure induced DNA damage, cell cycle arrest and necroptosis of ovarian granulosa cells in mice by promoting ROS production

The Science of The Total Environment, Год журнала: 2023, Номер 871, С. 161962 - 161962

Опубликована: Фев. 10, 2023

Язык: Английский

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Amino acid metabolism disorder and oxidative stress took part in EGCG alleviating Mn-caused ferroptosis via miR-9-5p/got1 axis

Journal of Hazardous Materials, Год журнала: 2025, Номер 489, С. 137656 - 137656

Опубликована: Фев. 21, 2025

Язык: Английский

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ROS-mediated PPAR/RXR inhibition contributes to acetochlor-induced apoptosis and autophagy in Ctenopharyngodon idella hepatic cells

Fish & Shellfish Immunology, Год журнала: 2022, Номер 128, С. 684 - 694

Опубликована: Авг. 24, 2022

Язык: Английский

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The endoplasmic reticulum-mitochondrial crosstalk is involved in the mitigation mechanism of eucalyptol on imidacloprid toxicity in Ctenopharyngodon idellus kidney cells

Fish & Shellfish Immunology, Год журнала: 2022, Номер 127, С. 99 - 108

Опубликована: Июнь 13, 2022

Язык: Английский

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Micro-algal astaxanthin improves lambda-cyhalothrin-induced necroptosis and inflammatory responses via the ROS-mediated NF-κB signaling in lymphocytes of carp (Cyprinus carpio L.)

Fish & Shellfish Immunology, Год журнала: 2023, Номер 139, С. 108929 - 108929

Опубликована: Июль 4, 2023

Язык: Английский

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A review of the influence of environmental pollutants (microplastics, pesticides, antibiotics, air pollutants, viruses, bacteria) on animal viruses

Journal of Hazardous Materials, Год журнала: 2024, Номер 468, С. 133831 - 133831

Опубликована: Фев. 19, 2024

Язык: Английский

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Eucalyptol alleviates avermectin exposure-induced apoptosis and necroptosis of grass carp hepatocytes by regulating ROS/NLRP3 axis

Aquatic Toxicology, Год журнала: 2023, Номер 264, С. 106739 - 106739

Опубликована: Окт. 30, 2023

Язык: Английский

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New insights into Microalgal astaxanthin's effect on Lambda-cyhalothrin-induced lymphocytes immunotoxicity in Cyprinus carpio: Involving miRNA-194-5p-FoxO1-mediated-mitophagy and pyroptosis

Fish & Shellfish Immunology, Год журнала: 2023, Номер 141, С. 109046 - 109046

Опубликована: Сен. 1, 2023

Язык: Английский

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Cadmium exposure causes mitochondrial fission and fusion disorder in the pig hypothalamus via the PI3K/AKT pathway

Ecotoxicology and Environmental Safety, Год журнала: 2022, Номер 242, С. 113880 - 113880

Опубликована: Июль 21, 2022

Cadmium (Cd) is the main environmental pollutant causing endocrine and nervous system dysfunction in animals. High doses of Cd cause cytotoxicity, including programmed necrosis apoptosis, which has aroused widespread concern. Mitochondrial dynamics plays a key role apoptosis organs. Nevertheless, there lack information on relationship between Cd-induced necrosis/apoptosis hypothalamus mitochondrial fusion-fission balance. Therefore, hypothalamic injury model exposure was established by adding 20 mg/kg CdCl2 to basic pig diet for 40 days. Analysis toxicity mechanism conducted inductively coupled plasma mass spectrometry, hematoxylin eosin staining, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay, quantitative reverse transcription-polymerase chain reaction, as well western blot analyses. The results suggested that inhibited expression PI3K AKT, interfered with balance fusion division, downregulated Mfn2, Mfn1, OPA1, upregulated Drp1 Mff, led cell hypothalamus. This study finds cadmium leads fission porcine via PI3K/AKT pathway.

Язык: Английский

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Cineole regulates Wnt/β-catenin pathway through Nrf2/keap1/ROS to inhibit bisphenol A-induced apoptosis, autophagy inhibition and immunosuppression of grass carp hepatocytes

Fish & Shellfish Immunology, Год журнала: 2022, Номер 131, С. 30 - 41

Опубликована: Окт. 1, 2022

Язык: Английский

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