Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus)

Aquatic Toxicology, Год журнала: 2023, Номер 261, С. 106630 - 106630

Опубликована: Июль 2, 2023

Язык: Английский

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Pseudomonas putida infection induces immune-antioxidant, hepato-renal, ethological, and histopathological/immunohistochemical disruptions in Oreochromis niloticus: the palliative role of titanium dioxide nanogel

BMC Veterinary Research, Год журнала: 2024, Номер 20(1)

Опубликована: Апрель 1, 2024

Abstract Background Pseudomonas putida is a pathogenic bacterium that induces great losses in fishes, including Nile tilapia ( Oreochromis niloticus ). Currently, the application of nanomaterials aquaculture practices has gained more success as it endows promising results therapies compared to traditional protocols. Objective Therefore, current perspective considered first report assess anti-bacterial efficacy titanium dioxide nanogel (TDNG) against P. ) tilapia. Methods The fish n = 200; average body weight: 47.50±1.32 g) were allocated into four random groups (control, TDNG, , and TDNG + ), where 0.9 mg/L was applied bath treatment for ten days. Results Outcomes revealed infection caused ethological alterations (surfacing, abnormal movement, aggression) depression immune-antioxidant variables (complement 3, lysozyme activity, total antioxidant capacity, superoxide dismutase, reduced glutathione content). Additionally, substantial elevation hepatorenal biomarkers (aspartate alanine aminotransferases creatinine) with clear histopathological changes immuno-histochemical (very weak BCL-2 potent caspase-3 immuno-expressions) seen. Surprisingly, treating putida- infected improved these obvious restoration tissue architectures. Conclusion Overall, this encompasses key role an agent controlling improving health status

Язык: Английский

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Antimicrobial efficacy of magnetite nanoparticles against Aeromonas sobria challenge in African catfish: Biochemical, protein profile, and immuno-antioxidant indices

Aquaculture Reports, Год журнала: 2023, Номер 32, С. 101692 - 101692

Опубликована: Авг. 3, 2023

Recently, researchers in aquaculture become interested green synthesized nanomaterials as a superior alternative to current conventional methodologies. The present work shows that Moringa oleifera magnetite nanoparticles (MS-Fe3O4NPs) might offer possible substitute for common antibiotics treat Aeromonas sobria infection African catfish (Clarias gariepinus). MS-Fe3O4NPs demonstrated an vitro antibacterial potential (21 mm inhibition zone) against A. sobria. fish (n = 120; average body weight: 90 ± 3.5 g) were randomized into four groups (control, MS-Fe3O4NPs, sobria, and + sobria), where 1.2 mg/L of was used bath treatment seven-days. caused substantial elevations malondialdehyde, tumor necrosis factor-alpha, stress indices, hepato-renal biomarkers well lower survival rate. Moreover, apparent depletion the level antioxidants, protein profile, immune indicators consequences infection. Surprisingly, sobria-infected with recovered these parameters. Hence, water additive show promise fish.

Язык: Английский

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Alleviating Effect of a Magnetite (Fe3O4) Nanogel against Waterborne-Lead-Induced Physiological Disturbances, Histopathological Changes, and Lead Bioaccumulation in African Catfish

Gels, Год журнала: 2023, Номер 9(8), С. 641 - 641

Опубликована: Авг. 8, 2023

Heavy metal toxicity is an important issue owing to its harmful influence on fish. Hence, this study a pioneer attempt verify the in vitro and vivo efficacy of magnetite (Fe3O4) nanogel (MNG) mitigating waterborne lead (Pb) African catfish. Fish (n = 160) were assigned into four groups for 45 days. The first (control) second exposed 0 1.2 mg L−1 MNG water. third fourth (MNG + Pb) water 69.30 Pb. In vitro, caused dramatic drop Pb level within 120 h. Pb-exposed group showed lowest survival (57.5%) among groups, with substantial elevations hepato-renal function lipid peroxide (MDA). Moreover, exposure remarkable decline protein-immune parameters hepatic antioxidants, along higher residual deposition muscles obvious histopathological changes liver kidney. Interestingly, adding aqueous fish relieved these alterations increased survivability. Thus, novel antitoxic agent against maintain health C. gariepinus.

Язык: Английский

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The anti-bacterial efficacy of zinc oxide nanoparticles synthesized by Nelumbo nucifera leaves against Clostridium perfringes challenge in Oreochromis niloticus

Aquaculture, Год журнала: 2023, Номер 578, С. 740030 - 740030

Опубликована: Авг. 28, 2023

Язык: Английский

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Impact of Streptococcus agalactiae Challenge on Immune Response, Antioxidant Status and Hepatorenal Indices of Nile Tilapia: The Palliative Role of Chitosan White Poplar Nanocapsule

Fishes, Год журнала: 2023, Номер 8(4), С. 199 - 199

Опубликована: Апрель 12, 2023

A new insight into the synthesis of herbal plant (White poplar, Poplus alba) leave extract using chitosan nanocapsule was studied. The in vitro antibacterial activity white poplar (CWPNC) against Streptococcus agalactiae (S. agalactiae) determined. About 120 fish were categorized for 7 days four groups. first and second groups treated with 0 mg/L 3 CWPNC water, respectively, without being challenged; group a control. third fourth (CWPNC + S. CWPNC, challenged (0.5 × 107 CFU/mL). obtained results revealed that had an agalactiae. Moreover, infection caused significant elevation (p < 0.05) lipid peroxidation (malondialdehyde) hepatorenal biomarkers, as well lowest survival rate (33.33%). depletion level antioxidants (catalase superoxide dismutase) immune indicators (immunoglobulin, lysozyme activity, complement 3) consequences infection. Treatment infected alleviated these bad circumstances.

Язык: Английский

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Nelumbo nucifera synthesized selenium nanoparticles modulate the immune-antioxidants, biochemical indices, and pro/anti-inflammatory cytokines pathways in Oreochromis niloticus infected with Aeromonas veronii

Fish & Shellfish Immunology, Год журнала: 2023, Номер 144, С. 109287 - 109287

Опубликована: Дек. 12, 2023

Язык: Английский

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Silicon nanoparticles vs trace elements toxicity: Modus operandi and its omics bases

Frontiers in Plant Science, Год журнала: 2024, Номер 15

Опубликована: Апрель 3, 2024

Phytotoxicity of trace elements (commonly misunderstood as ‘heavy metals’) includes impairment functional groups enzymes, photo-assembly, redox homeostasis, and nutrient status in higher plants. Silicon nanoparticles (SiNPs) can ameliorate element toxicity. We discuss SiNPs response against several essential (such Cu, Ni, Mn, Mo, Zn) non-essential (including Cd, Pb, Hg, Al, Cr, Sb, Se, As) elements. hinder root uptake transport the first line defence. charge plant antioxidant defence elements-induced oxidative stress. The enrolment gene expressions was also noticed on many occasions. These genes are associated with anatomical physiological phenomena, such cell wall composition, photosynthesis, metal transport. On this note, we dedicate later sections review to support an enhanced understanding influence metabolomic, proteomic, genomic profile plants under

Язык: Английский

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Aquatic assessment of the chelating ability of Silica-stabilized magnetite nanocomposite to lead nitrate toxicity with emphasis to their impact on hepatorenal, oxidative stress, genotoxicity, histopathological, and bioaccumulation parameters in Oreochromis niloticus and Clarias gariepinus

BMC Veterinary Research, Год журнала: 2024, Номер 20(1)

Опубликована: Июнь 18, 2024

Abstract Background In recent years, anthropogenic activities have released heavy metals and polluted the aquatic environment. This study investigated ability of silica-stabilized magnetite (Si-M) nanocomposite materials to dispose lead nitrate (Pb(NO 3 ) 2 toxicity in Nile tilapia African catfish. Results Preliminary tests were conducted determined median lethal concentration (LC 50 catfish be 5 mg/l. The sublethal concentration, equivalent 1/20 96-hour LC Pb(NO , was selected for our experiment. Fish each species divided into four duplicated groups. first group served as control negative group, while second (Pb group) exposed 0.25 mg/l (1/20 ). third (Si-MNPs) nanoparticles at a 1 mg/l, fourth + Si-MNPs) simultaneously Si-MNPs same concentrations Throughout experimental period, no mortalities or abnormal clinical observations recorded any treated groups, except melanosis nervous behavior observed some fish Pb group. After three weeks exposure, we analyzed hepatorenal indices, oxidative stress parameters, genotoxicity. Values alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), urea, creatinine significantly higher Pb-intoxicated groups compared both species. Oxidative parameters showed significant decrease reduced glutathione (GSH) along with increase malondialdehyde (MDA) protein carbonyl content (PCC) concentrations, well DNA fragmentation percentage However, these values nearly restored levels High accumulation liver gills least muscles Histopathological analysis tissue samples from Pb-exposed revealed brain vacuolation, gill fusion, hyperplasia, marked hepatocellular renal necrosis, contrasting Si-MNP which appeared an apparently normal structure. Conclusions Our results demonstrate that are safe effective aqueous additives reducing toxic effects (NO on through lead-chelating water before being absorbed by fish.

Язык: Английский

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Concentrations, characteristics, and human health exposure assessment of microplastics and heavy metals in freshwater fish in a potable water supply reservoire

Environmental Science and Pollution Research, Год журнала: 2025, Номер unknown

Опубликована: Март 25, 2025

Язык: Английский

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