Royal Society of Chemistry eBooks,
Год журнала:
2024,
Номер
unknown, С. 251 - 285
Опубликована: Ноя. 15, 2024
The
encapsulation
of
active
pharmaceutical
ingredients
(APIs)
in
microbeads
is
an
essential
step
drug
delivery;
however,
it
also
inherently
associated
with
the
need
to
control
particle
size
and
release
profiles.
Nevertheless,
most
conventional
methods
microencapsulation
fail
provide
consistent
results.
A
new
method
called
vibration-assisted
microbead
coating
a
novel
unified
technique
utilizing
mechanical
vibrations
enable
controlled,
uniform
on
APIs.
This
chapter
discusses
technology
performed
by
authors
through
formation
physical
activity
focuses
achieving
final
coated
surface
API,
shape,
size,
loading
vibration
parameters.
Additionally,
this
biocompatibility
stability
surface.
means
has
high
potential
for
delivery.
reduces
traditional
challenges
encapsulation,
if
not
eliminates
them,
more
reliable.
Based
abovementioned
findings,
propose
following
main
areas
their
further
work:
optimisation
parameters
various
APIs,
research
into
long-term
loading–release
profile,
possible
use
targeted
Environmental Science Nano,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
In
response
to
the
limited
environmentally
relevant
biobased
nanoplastic
models,
formation
of
poly(lactic
acid)
nanoplastics
with
comparable
properties
ones
deriving
from
environmental
ageing
debris,
is
presented.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(14), С. 7542 - 7542
Опубликована: Июль 9, 2024
Zeolite
type
5A
combined
with
the
magnetic
properties
of
maghemite
nanoparticles
facilitate
rapid
absorption
heavy
metals,
which
makes
them
an
interesting
proposal
for
remediation
water
contaminated
lead
and
arsenic.
However,
physicochemical
analysis
related
to
concentration
size
use
this
zeolite
composite
(MZ0)
in
bodies
possible
toxicological
effects
on
aquatic
fauna
has
not
yet
been
carried
out.
The
main
objective
research
work
is
determine
lethal
concentrations
that
cause
damage
Daphnia
magna
based
LC50
tests,
morphology,
reproductive
rate,
quantification
expression
three
genes
closely
involved
morphological
development
vital
structures
(Glass,
NinaE,
Pph13).
To
achieve
objective,
populations
neonates
young
individuals
were
used,
results
showed
was
11,314
mg
L−1,
while
individuals,
it
0.0310
L−1.
Damage
evidenced
by
a
decrease
eye
neonates,
increase
variations
caudal
spine
both
age
groups,
slight
increases
heart
size,
body,
antenna
groups.
rate
affected
lower
MZ0,
decreased
more
than
50%
from
minimum
exposure
MZ0.
And
ages,
Glass
gene
levels
as
MZ0
increased.
Also,
its
affinity
exoskeleton
D.
magna,
observed
using
light
microscopy
electron
microscopy.
It
concluded
did
generate
significant
mortality,
or
at
concentrations,
demonstrating
importance
evaluating
impacts
different
life
stages
cladoceran.
