Effect of the composition of a biologically active dietary supplement with macrofungi mycelia on its antioxidant activity DOI Creative Commons
Tetiana Krupodorova, Т. А. Butkevych, Victor Barshteyn

и другие.

Regulatory Mechanisms in Biosystems, Год журнала: 2024, Номер 15(4), С. 932 - 938

Опубликована: Ноя. 6, 2024

The global demand for macrofungi is driven by their rich content of biologically active substances and trends such as the need natural medicines, growing popularity vegan diets, increased consumer interest in therapeutic prophylactic dietary supplements, expanding use fungi food, pharmaceutical, cosmetic industries. aim this study was to investigate effect composition a supplement based on mixture macrofungal mycelium total phenolic antioxidant activity supplement. Fomitopsis pinicola, Pleurotus ostreatus Trametes versicolor were obtained through controlled submerged static cultivation suitable media. powdered mycelia F. P. ostreatus, T. versicolor, which are cubic plate-shaped conglomerates with rounded edges, translucent, smooth surface, mixed excipients granulated. Pharmacotechnological characteristics compressibility, powder flowability, moisture content, well dosage uniformity disintegration time hard capsules significantly varied depending granulate composition. each mixture, selected granulates, determined. Differences insignificant. Determination these parameters pharmacotechnological granulates allowed identification most excipients: lactose monohydrate (5%), mannitol:microcrystalline cellulose 101 ratio 2:1 (10%), sodium croscarmellose (1%), 0.7% solution carboxymethyl (4%). This contains 29.83 ± 0.49 mg GAE/g can neutralize DPPH free radical scavenging 86.53 0.62%. results confirm prospects using promising raw material development new activity.

Язык: Английский

The bioactive compounds, beneficial medicinal properties, and biotechnological prospects of Fomitopsis: a comprehensive overview DOI Creative Commons
Samantha C. Karunarathna, Nimesha M. Patabendige, Jaturong Kumla

и другие.

Frontiers in Cellular and Infection Microbiology, Год журнала: 2025, Номер 15

Опубликована: Апрель 22, 2025

Members of the genus Fomitopsis are medicinal mushrooms and a rich source bioactive compounds with significant pharmacological biotechnological potential. This paper provides comprehensive review their secondary metabolites, including polysaccharides, terpenoids, phenolic compounds. In addition, chemical structures biological activities described in detail. These exhibit antioxidant, antimicrobial, anti-inflammatory, immunomodulatory properties, promising applications cancer therapy, cardiovascular health, immune modulation. Beyond medicine, plays crucial role biotechnology, contributing to bioremediation, biofuel production, pharmaceutical development, functional food innovation. By integrating traditional knowledge recent scientific advances, this highlights biomedical significance industrial relevance , underscoring its expanding health environmental sustainability.

Язык: Английский

Процитировано

0

Electrochemical, Thermodynamic and DFT Studies of Fomitopsis pinicola as Green Corrosion Inhibitor for Carbon Steel in Sulfuric Acid DOI

J.J. Martinez-Gonzalez,

Isaac Tello-Salgado, A. K. Larios-Gálvez

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1321, С. 140014 - 140014

Опубликована: Сен. 10, 2024

Язык: Английский

Процитировано

2

Enhancement of antioxidant activity and total phenolic content of Fomitopsis pinicola mycelium extract DOI Creative Commons
Tetiana Krupodorova, Victor Barshteyn, Veronika Dzhagan

и другие.

Fungal Biology and Biotechnology, Год журнала: 2024, Номер 11(1)

Опубликована: Ноя. 7, 2024

Fomitopsis pinicola is one of the most common fungi found in temperate zone Europe, widely distributed spread Asia and North America. Fungus has a wide range therapeutic activity: antitumor, antimicrobial, anti-inflammatory, antidiabetic, antifungal, hepatoprotective, hemostatic action. A number studies have confirmed significant antioxidant activity F. fruiting bodies. However, controlled cultivation conditions that influence fungal growth metabolite production pinicola, particularly mycelial biosynthesis metabolites its culture broth, as well mycelium, remain poorly understood.

Язык: Английский

Процитировано

2

Electrochemical, Thermodynamic and Dft Studies of Fomitopsis Pinicola As Green Corrosion Inhibitor for Carbon Steel in Acid Media DOI
J.G. González-Rodrı́guez,

J.J. Martinez-Gonzalez,

Isaac Tello-Salgado

и другие.

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0

Effect of the composition of a biologically active dietary supplement with macrofungi mycelia on its antioxidant activity DOI Creative Commons
Tetiana Krupodorova, Т. А. Butkevych, Victor Barshteyn

и другие.

Regulatory Mechanisms in Biosystems, Год журнала: 2024, Номер 15(4), С. 932 - 938

Опубликована: Ноя. 6, 2024

The global demand for macrofungi is driven by their rich content of biologically active substances and trends such as the need natural medicines, growing popularity vegan diets, increased consumer interest in therapeutic prophylactic dietary supplements, expanding use fungi food, pharmaceutical, cosmetic industries. aim this study was to investigate effect composition a supplement based on mixture macrofungal mycelium total phenolic antioxidant activity supplement. Fomitopsis pinicola, Pleurotus ostreatus Trametes versicolor were obtained through controlled submerged static cultivation suitable media. powdered mycelia F. P. ostreatus, T. versicolor, which are cubic plate-shaped conglomerates with rounded edges, translucent, smooth surface, mixed excipients granulated. Pharmacotechnological characteristics compressibility, powder flowability, moisture content, well dosage uniformity disintegration time hard capsules significantly varied depending granulate composition. each mixture, selected granulates, determined. Differences insignificant. Determination these parameters pharmacotechnological granulates allowed identification most excipients: lactose monohydrate (5%), mannitol:microcrystalline cellulose 101 ratio 2:1 (10%), sodium croscarmellose (1%), 0.7% solution carboxymethyl (4%). This contains 29.83 ± 0.49 mg GAE/g can neutralize DPPH free radical scavenging 86.53 0.62%. results confirm prospects using promising raw material development new activity.

Язык: Английский

Процитировано

0