Relationship between Subjective Grip Strength and Physical Functioning among Community-Dwelling Older Women DOI Creative Commons

Kohei Iwamoto,

Yuki Kikuchi,

Hideki Nakano

и другие.

Geriatrics, Год журнала: 2024, Номер 9(3), С. 68 - 68

Опубликована: Май 26, 2024

This study investigated the relationship between subjective grip strength and physical function in community-dwelling older women. Subjective was assessed using a questionnaire, body composition were compared groups with strong weak strength. Additionally, two those mild cognitive impairment (MCI) normal function, respectively. The results showed significant differences (p < 0.001), 30 s chair–stand (CS-30) test = 0.039), timed up-and-go (TUG) 0.027), maximal gait speed 0.029), skeletal muscle mass 0.001). Older adults quadriceps 0.009), one-leg standing time 0.041), CS-30 0.002), TUG 0.014), 0.006), 0.003). low had lower mass. However, no items among MCI. Thus, is an indicator of overall decline reduction adults, should be considered when assessing adults.

Язык: Английский

Longitudinal patterns of brain aging and neurodegeneration among older adults with dual decline in memory and gait DOI Creative Commons
Qu Tian,

Erin E. Greig,

Keenan A. Walker

и другие.

Alzheimer s & Dementia, Год журнала: 2025, Номер 21(2)

Опубликована: Фев. 1, 2025

Abstract INTRODUCTION Dual cognitive and mobility decline is more strongly associated with dementia risk than only. It remains unknown whether this syndrome brain atrophy patterns, white matter (WM) damage, or pathology. METHODS In the Baltimore Longitudinal Study of Aging participants without dual decline, we used linear mixed‐effects models to compare up 13‐year longitudinal changes in MRI‐derived WM hyperintensities ( n = 339), microstructure 307), plasma glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), amyloid beta 42/40 (Aβ ) ratio 349), phosphorylated tau 181 (pTau181) 258). RESULTS Those experiencing showed accelerated medial temporal p .004), parietotemporal .029), perisylvian regions .028), whereas gait only .035) memory .021). was also unique microstructural deterioration several tracts < .05), a greater decrease Aβ .015), increases GFAP .009) NfL .001). DISCUSSION Individuals are at an increased for regional atrophy, degradation, biomarker‐defined molecular underlying dementia. Highlights patterns. deterioration. ratio. NfL. may indicate blood markers

Язык: Английский

Процитировано

1

Relationship between Subjective Grip Strength and Physical Functioning among Community-Dwelling Older Women DOI Creative Commons

Kohei Iwamoto,

Yuki Kikuchi,

Hideki Nakano

и другие.

Geriatrics, Год журнала: 2024, Номер 9(3), С. 68 - 68

Опубликована: Май 26, 2024

This study investigated the relationship between subjective grip strength and physical function in community-dwelling older women. Subjective was assessed using a questionnaire, body composition were compared groups with strong weak strength. Additionally, two those mild cognitive impairment (MCI) normal function, respectively. The results showed significant differences (p < 0.001), 30 s chair–stand (CS-30) test = 0.039), timed up-and-go (TUG) 0.027), maximal gait speed 0.029), skeletal muscle mass 0.001). Older adults quadriceps 0.009), one-leg standing time 0.041), CS-30 0.002), TUG 0.014), 0.006), 0.003). low had lower mass. However, no items among MCI. Thus, is an indicator of overall decline reduction adults, should be considered when assessing adults.

Язык: Английский

Процитировано

0