International Journal of Cosmetic Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 11, 2024
The
hair
shaft
is
often
exposed
to
shampoo
and
haircare
products
that
have
unknown
or
varying
pH
levels.
These
contain
a
combination
of
surfactants
other
active
ingredients
treat
the
scalp.
As
amphoteric
proteins,
keratins
limited
buffering
capacity,
so
variations
in
can
multifaceted
impacts
on
them.
However,
there
knowledge
about
how
affects
keratin-associated
proteins
(KAPs).
Therefore,
this
study
aims
examine
effects
levels
(pH
3-pH
12)
structure
analyse
consequent
alterations
proteome
using
mass
spectrometry-based
proteomics.
Molecules,
Год журнала:
2024,
Номер
29(12), С. 2876 - 2876
Опубликована: Июнь 17, 2024
Background:
Androgenetic
alopecia
(AGA)
causes
thinning
hair,
but
poor
hair
quality
in
balding
areas
and
damage
from
UV
radiation
have
been
overlooked.
Plant
extracts
like
Platycladus
orientalis
flavonoids
(POFs)
may
improve
AGA.
This
study
examines
POFs’
effectiveness
treating
AGA-affected
repairing
UV-induced
damage.
Methods:
Hair
samples
were
analyzed
using
scanning
electron
microscopy
(SEM)
to
examine
surface
characteristics,
paramagnetic
resonance
(EPR)
spectroscopy
measure
free
radicals
the
spectrophotometry
assess
changes
properties.
Results:
POFs
effectively
removed
hydroxyl
keratinocytes
had
antioxidant
They
also
reduced
AGA
by
mitigating
production
of
melanin
radicals.
Following
POF
treatment,
reduction
peroxidized
lipid
loss
was
notable
at
59.72%,
thereby
delaying
progression
color
change.
Moreover,
protein
decreased
191.1
μ/g
tryptophan
15.03%,
ultimately
enhancing
hair’s
tensile
strength.
Conclusion:
compared
healthy
damaged
shows
more
pronounced
signs
when
exposed
radiation.
help
protect
reducing
oxidative
slowing
down
degradation.
International Journal of Cosmetic Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 11, 2024
The
hair
shaft
is
often
exposed
to
shampoo
and
haircare
products
that
have
unknown
or
varying
pH
levels.
These
contain
a
combination
of
surfactants
other
active
ingredients
treat
the
scalp.
As
amphoteric
proteins,
keratins
limited
buffering
capacity,
so
variations
in
can
multifaceted
impacts
on
them.
However,
there
knowledge
about
how
affects
keratin-associated
proteins
(KAPs).
Therefore,
this
study
aims
examine
effects
levels
(pH
3-pH
12)
structure
analyse
consequent
alterations
proteome
using
mass
spectrometry-based
proteomics.