Nutrients, Год журнала: 2024, Номер 16(15), С. 2570 - 2570
Опубликована: Авг. 5, 2024
We aimed to characterize the anti-obesity and anti-atherosclerosis effects of Lactobacillus curvatus HY7601 plantarum KY1032 using high-fat diet (HFD)-fed obese C57BL/6 mice. divided mice into control (CON), HFD, HFD with 108 CFU/kg/day probiotics (HFD + KL, HY7301:KY1032 = 1:1), 109 KH, 1:1) groups fed/treated them during 7 weeks. The body mass, brown adipose tissue (BAT), inguinal white (iWAT), epididymal (eWAT) masses total cholesterol triglyceride concentrations were remarkably lower in probiotic-treated than group a dose-dependent manner. In addition, expression uncoupling protein 1 BAT, iWAT, eWAT was significantly higher mice, as demonstrated by immunofluorescence staining Western blotting. also measured transport genes liver jejunum found that those encoding liver-X-receptor α, ATP-binding cassette transporters G5 G8, 7α-hydroxylase KH Thus, mixture concentration can assist weight regulation through management lipid metabolism thermogenesis.
Язык: Английский