Synergistic cancer treatment using porphyrin-based metal-organic Frameworks for photodynamic and photothermal therapy DOI
Mahsa Akbari Oryani, Mojtaba Tarin,

Leila Rahnama Araghi

и другие.

Journal of drug targeting, Год журнала: 2024, Номер unknown, С. 1 - 19

Опубликована: Дек. 2, 2024

Recent advancements in multifunctional nanomaterials for cancer therapy have highlighted porphyrin-based metal-organic frameworks (MOFs) as promising candidates due to their unique properties and versatile applications. This overview focuses on the use of MOFs combined photodynamic (PDT) photothermal (PTT) treatment. Porphyrin-based offer high porosity, tuneable structures, excellent stability, making them ideal drug delivery therapeutic The incorporation porphyrin molecules into MOF framework enhances light absorption energy transfer, leading improved effects. Additionally, porosity allows encapsulation agents, further enhancing efficacy. In PDT, generate reactive oxygen species (ROS) upon activation, destroying cells. enable conversion heat, resulting localised hyperthermia tumour ablation. combination PDT PTT a single platform offers synergistic effects, better outcomes, reduced side selectivity. dual-modal treatment strategy provides precise spatiotemporal control over process, paving way next-generation therapeutics with enhanced efficacy Further research optimisation are needed clinical

Язык: Английский

Manganese-Based Nanosystems: Advancing MRI and Multimodal Imaging Agents DOI
Lorenzo Tei, Mauro Botta, Carlos F. G. C. Geraldes

и другие.

Опубликована: Янв. 1, 2025

Процитировано

0

Advances in Organic Porous Polymeric‐Supported Photothermal Phase Change Materials DOI Creative Commons
Fulai Zhao,

Weikang Yuan,

Huiyu Chen

и другие.

Carbon Energy, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

ABSTRACT The urgent demand for renewable energy solutions, propelled by the global crisis and environmental concerns, has spurred creation of innovative materials solar thermal storage. Photothermal phase change (PTPCMs) represent a novel type composite material (PCM) aimed at improving storage efficiency incorporating photothermal into traditional PCMs encapsulating them within porous structures. Various encapsulation have been studied, including carbon, expanded graphite, ceramics, but issues like brittleness hinder their practical use. To overcome these limitations, flexible PTPCMs using organic polymers—like foams, hydrogels, wood—have emerged, offering high porosity lightweight characteristics. This review examines recent advancements in preparation based on polymer supports through techniques impregnation situ polymerization, assessing impact different PCM performance clarifying mechanisms conversion heat Subsequently, most applications polymer‐based are systematically summarized, future research challenges possible solutions discussed. aims to foster awareness about potential promoting environmentally friendly practices catalyzing further this promising field.

Язык: Английский

Процитировано

0

Study on synergistic mechanism of Cu-TCPP@MnO2 composites for photothermal/photodynamic/chemodynamic treatment of infected wound healing DOI
Jiawei Li, Zhigang Chu,

Shimeng Wang

и другие.

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162334 - 162334

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Synergistic cancer treatment using porphyrin-based metal-organic Frameworks for photodynamic and photothermal therapy DOI
Mahsa Akbari Oryani, Mojtaba Tarin,

Leila Rahnama Araghi

и другие.

Journal of drug targeting, Год журнала: 2024, Номер unknown, С. 1 - 19

Опубликована: Дек. 2, 2024

Recent advancements in multifunctional nanomaterials for cancer therapy have highlighted porphyrin-based metal-organic frameworks (MOFs) as promising candidates due to their unique properties and versatile applications. This overview focuses on the use of MOFs combined photodynamic (PDT) photothermal (PTT) treatment. Porphyrin-based offer high porosity, tuneable structures, excellent stability, making them ideal drug delivery therapeutic The incorporation porphyrin molecules into MOF framework enhances light absorption energy transfer, leading improved effects. Additionally, porosity allows encapsulation agents, further enhancing efficacy. In PDT, generate reactive oxygen species (ROS) upon activation, destroying cells. enable conversion heat, resulting localised hyperthermia tumour ablation. combination PDT PTT a single platform offers synergistic effects, better outcomes, reduced side selectivity. dual-modal treatment strategy provides precise spatiotemporal control over process, paving way next-generation therapeutics with enhanced efficacy Further research optimisation are needed clinical

Язык: Английский

Процитировано

1