Stress, microbiota, and the gut–brain axis in mental and digestive health

Medicina Clínica, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Using synthetic biology to understand the gut-brain axis

Cell Reports Physical Science, Год журнала: 2025, Номер unknown, С. 102458 - 102458

Опубликована: Фев. 1, 2025

Язык: Английский

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Communities, mysteries, and pathophysiologies – Are gut microbes key to a healthy mind?

Brain Behavior and Immunity, Год журнала: 2025, Номер 125, С. 330 - 331

Опубликована: Янв. 21, 2025

Язык: Английский

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The role of the gut microbiome in Alzheimer's disease pathophysiology

Current Opinion in Neurology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 7, 2025

Purpose of review The present aims to provide an overview the existing understanding role gut microbiome in Alzheimer's disease pathophysiology. Recent findings research has highlighted significant pathogenesis via gut-brain axis. However, precise mechanisms by which and its microbial metabolites influence brain function are not clearly understood. Various factors, such as diet, drugs, lifestyle, stress, infections can provoke imbalance homeostasis, known dysbiosis. This dysbiosis impacts intestinal blood-brain barrier permeability, elevating pro-inflammatory cytokines contributing neurodegeneration. Moreover, generates neurotransmitters, amyloids, neurotoxins, metabolites, may play a systemic inflammation disruption physiological barriers. Summary In past decade, advancements analysis technologies bioinformatics have significantly enhanced our disease. plays pivotal regulatory progression disease, closely interacts with pathogenesis, encompassing inflammation, amyloidosis, neurodegeneration, tauopathy, co-pathologies.

Язык: Английский

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Stress, microbiota, and the gut–brain axis in mental and digestive health

Medicina Clínica (English Edition), Год журнала: 2025, Номер 164(6), С. 295 - 304

Опубликована: Март 1, 2025

Язык: Английский

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