Advances in human umbilical cord mesenchymal stem cells-derived extracellular vesicles and biomaterial assemblies for endometrial injury treatment

World Journal of Stem Cells, Год журнала: 2025, Номер 17(1)

Опубликована: Янв. 17, 2025

Endometrial injury caused by repeated uterine procedures, infections, inflammation, or artery dysfunction can deplete endometrial stem/progenitor cells and impair regeneration, thereby diminishing receptivity evidently lowering the live birth, clinical pregnancy, embryo implantation rates. Currently, safe effective treatment methods gene-targeted therapies are unavailable, especially for severe injury. Umbilical cord mesenchymal stem their extracellular vesicles characterized simple collection, rapid proliferation, low immunogenicity, tumorigenicity, along with involvement in regulating angiogenesis, immune response, cell apoptosis inflammatory fibrosis, Therefore, these hold broad potential application repair. This article reviewed recent research on human umbilical as well repairing

Язык: Английский

Mefentrifluconazole exposure disrupted hepatic lipid metabolism disorder tightly associated with gut barrier function abnormal in mice

The Science of The Total Environment, Год журнала: 2023, Номер 905, С. 167317 - 167317

Опубликована: Сен. 23, 2023

Язык: Английский