Intelligent Sensing Switches in Drug Delivery Systems: Mechanisms, Material Selection, and Future Perspectives DOI
Fuyu Chen, Heng Li,

Chengdong Zhen

и другие.

Journal of Biomedical Materials Research Part A, Год журнала: 2025, Номер 113(6)

Опубликована: Май 30, 2025

ABSTRACT The intelligence and controllability of drug delivery systems (DDS) are crucial for enhancing therapeutic efficacy minimizing side effects. Among these, DDS responsive switches play a pivotal role in precisely regulating the timing spatial distribution release response to specific physiological environments within body or external stimuli. Based on origin stimuli, they can be categorized into endogenous exogenous This paper reviews various types stimulus‐responsive switches, including dual‐stimulus elaborates mechanisms each intelligent switch. It summarizes advantages limitations different systems, highlights properties commonly used temperature‐sensitive materials, discusses applications popular nano‐engineered materials pH electromagnetic‐responsive switches. Finally, provides an outlook future DDS, focusing achieving more precise control, as well ensuring clinical stability reliability.

Язык: Английский

Engineered Conductive Metal–organic Frameworks for Electrochemical Detection of Urinary Biomarkers DOI
Brij Mohan, Muhammad Bilal Asif, Armando J. L. Pombeiro

и другие.

Small, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 22, 2024

Abstract The increasing prevalence of health concerns has sparked a demand for advanced monitoring tools, which is significant challenge researchers. Analysis biofluid samples and biomarker vital comprehensive assessment. In this context, metal–organic frameworks (MOFs) have emerged as one the leading materials developing cutting‐edge artificial sensors. These unique MOFs been developed from metallic organic linkers consist tunable pores dynamic surface areas, attracting various guest molecules to participate in electrochemical devices. This study gateway world where MOF designs transcend mere inventions, morphing into electric marvels that revolutionize urine sample monitoring. From inception design fabrication sensors tailored applications, prides itself on elucidating factors affecting MOF‐based electrical devices Moreover, focus placed conductivity, electrode properties, recent state‐of‐the‐art analysis, highlighting pivotal role biomarkers play honing resilience performance Finally, specific used analysis. It will attract researchers develop new portable tools by analyzing samples.

Язык: Английский

Процитировано

7

Zinc-based metal–organic frameworks as efficient carriers in combination therapy for hepatocellular carcinoma treatment DOI

Xiao-Xuan Zeng,

Bo-Cheng Chen,

Xiang-Xin Cao

и другие.

Inorganic Chemistry Communications, Год журнала: 2025, Номер 174, С. 113921 - 113921

Опубликована: Янв. 10, 2025

Язык: Английский

Процитировано

0

A review on integrated design and application of stimuli-responsive ZIF-8 metal-organic frameworks for breast cancer theranostics DOI
Abhishek Jha, Sanchit Arora,

Rohan Chand Sahu

и другие.

Next Materials, Год журнала: 2025, Номер 8, С. 100611 - 100611

Опубликована: Март 22, 2025

Язык: Английский

Процитировано

0

Insight into optimization of doxorubicin removal by a novel nanobiocomposite of doped molybdenum carbide and zinc ferrite onto pomegranate peels nanobiochar (Mo2C-ZnFe2O4@PPNB) DOI

Saja Abdulrahman Althobaiti,

Gehan M. Nabil, Mohamed E. Mahmoud

и другие.

Journal of Molecular Liquids, Год журнала: 2025, Номер unknown, С. 127597 - 127597

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Intelligent Sensing Switches in Drug Delivery Systems: Mechanisms, Material Selection, and Future Perspectives DOI
Fuyu Chen, Heng Li,

Chengdong Zhen

и другие.

Journal of Biomedical Materials Research Part A, Год журнала: 2025, Номер 113(6)

Опубликована: Май 30, 2025

ABSTRACT The intelligence and controllability of drug delivery systems (DDS) are crucial for enhancing therapeutic efficacy minimizing side effects. Among these, DDS responsive switches play a pivotal role in precisely regulating the timing spatial distribution release response to specific physiological environments within body or external stimuli. Based on origin stimuli, they can be categorized into endogenous exogenous This paper reviews various types stimulus‐responsive switches, including dual‐stimulus elaborates mechanisms each intelligent switch. It summarizes advantages limitations different systems, highlights properties commonly used temperature‐sensitive materials, discusses applications popular nano‐engineered materials pH electromagnetic‐responsive switches. Finally, provides an outlook future DDS, focusing achieving more precise control, as well ensuring clinical stability reliability.

Язык: Английский

Процитировано

0