PROTCROWN: A Manually Curated Resource of Protein Corona Data for Unlocking the Potential of Protein–Nanoparticle Interactions

Nano Letters, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

The emergence of the "Protein Corona" is a pivotal concept in bioinformatics and nanotechnology, crucial for understanding nanomedicine delivery nanoparticle–biological entity interactions. After entering biological fluid, such as blood, nanoparticles (NPs, nanomedical carriers) are quickly coated with proteins, forming protein interface layer called corona. An in-depth investigation into corona essential elucidating ramifications NPs their prospective applications within medical field beyond. To advance our intricate interactions between systems, we have developed PROTCROWN, inaugural database. This resource systematically curates organizes data relevant to corona, facilitating advanced analysis research field. It provides convenient query platform researchers supports visualization analysis. Our database, accessible at http://www.protcrown.cn.

Язык: Английский

Dual-responsive and NIR-triggered Detachable Nanoplatform for Integrated Thrombolytic and Antiplatelet Therapy

Asian Journal of Pharmaceutical Sciences, Год журнала: 2025, Номер unknown, С. 101035 - 101035

Опубликована: Фев. 1, 2025

Язык: Английский