Hormone and Metabolic Research,
Год журнала:
2023,
Номер
56(02), С. 111 - 117
Опубликована: Дек. 4, 2023
Abstract
The
coronavirus
disease
2019
(COVID-19)
pandemic
caused
by
severe
acute
respiratory
syndrome
2
(SARS-CoV-2)
has
led
to
the
development
of
various
vaccines.
Reports
have
emerged
suggesting
a
possible
association
between
SARS-CoV-2
vaccination
and
onset
thyroid
diseases.
This
review
explores
clinical
aspects
disorders
following
vaccination,
including
case
report
patient
with
concomitant
subacute
thyroiditis
(SAT)
Graves’
(GD)
blocking
thyrotropin
receptor
autoantibodies
(TSH-R-Ab)
vaccination.
SAT,
characterized
transient
inflammation
gland,
been
reported
after
GD,
an
autoimmune
hyperthyroidism,
also
observed
post-vaccination,
often
stimulating
TSH-R-Ab.
orbitopathy
(GO)
associated
in
patients
history
immune
disease.
unique
underscores
very
rare
condition
functional
hypothyroidism
relation
usefulness
analysis
TSH-R-Ab
that
can
provide
valuable
insights
into
pathogenesis
help
guide
treatment.
highlights
need
for
continued
monitoring
awareness
potential
thyroid-related
complications
Endocrinology and Metabolism,
Год журнала:
2023,
Номер
38(4), С. 455 - 461
Опубликована: Авг. 8, 2023
The
correlation
between
acute
coronavirus
disease
2019
(COVID-19)
and
subacute
thyroiditis
(SAT)
has
not
been
clearly
investigated
in
"long
COVID"
patients.
We
aimed
to
investigate
the
incidence
of
SAT
during
convalescence
after
phase
COVID-19,
comparing
with
that
general
population.Data
from
a
total
422,779
COVID-19
patients
control
group
2,113,895
individuals
were
analyzed.
index
date
was
defined
as
3
months
confirmation
COVID-19.
rate
(IR)
hazard
ratios
(HRs)
calculated
per
100,000
persons.
Subgroup
analysis
included
HRs
90-179
180
days
post-COVID-19
diagnosis;
additional
conducted
according
hospitalization
status,
sex,
age
group.The
IR
17.28
persons
(95%
confidence
interval
[CI],
12.56
23.20)
8.63
CI,
6.37
11.45)
group.
HR
1.76
1.01
3.06;
P=0.045).
1.39
0.82
2.34;
P=0.220)
up
6
2.30
1.60
3.30;
P<0.001)
beyond
months.
for
among
2.00
1.41
2.83)
hospitalized
3.06)
non-hospitalized
compared
27.09
20.04
35.82)
females
6.47
3.34
11.30)
males.
In
19
64
group,
18.19
13.70
23.67),
while
9.18
7.72
10.84)
65
69
group.SAT
could
be
potential
long-term
complication
Long-term
surveillance
thyroid
dysfunction
is
needed
especially
hospitalized,
female
young-aged
subjects.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Март 5, 2024
Abstract
Determination
of
long
COVID
requires
ruling
out
alternative
diagnoses,
but
there
has
been
no
report
on
the
features
diagnoses.
This
study
was
a
single-center
retrospective
outpatients
who
visited
our
clinic
between
February
2021
and
June
2023
that
carried
to
determine
characteristics
diagnoses
in
patients
with
post-COVID-19
symptoms.
In
total
731
patients,
50
(6.8%)
were
newly
diagnosed
52
diseases
requiring
medical
intervention,
16
(32%)
those
(2.2%
total)
considered
have
priority
for
treatment
disorders
over
treatment.
The
proportion
new
diagnosis
increased
advance
age,
15.7%
aged
60
years
or
older
having
diagnosis.
Endocrine
metabolic
hematological
respiratory
most
common,
being
detected
eight
(16%)
each.
Although
35
(67%)
related
their
symptoms,
endocrine
least
associated
specific
Other
require
attention
found
especially
elderly
symptomatic
COVID.
Thus,
appropriate
assessment
differentiation
from
are
necessary
managing
Current Oncology,
Год журнала:
2024,
Номер
31(9), С. 5528 - 5536
Опубликована: Сен. 16, 2024
Background:
Differentiated
thyroid
carcinoma
(DTC),
mainly
papillary
(PTC),
at
low
risk
of
recurrence
is
currently
managed
with
active
surveillance
strategies
or
less
aggressive
surgeries.
However,
total
thyroidectomy
131I
treatment
still
performed
both
if
these
tumors
are
diagnosed
before
occasionally
after
surgery.
This
real-life
study
aimed
to
evaluate
the
rate
biochemical,
structural,
and
functional
events
in
a
large
series
consecutive
DTCs
treated
by
thyroidectomy,
but
not
131I,
medium–long-term
follow-up.
Patients
Methods:
We
evaluated
clinical–pathologic
data
383
patients
(2006–2012)
unifocal
DTC
[T1a/b(s)]
recurrence,
without
lymph
node
dissection
were
detected
during
Results:
Females
accounted
for
75.7%
our
group,
median
age
was
50
years.
The
tumor
dimension
0.4
cm
(range
0.1–1.2).
Most
had
T1a
(98.9%),
73.6%
classic
variant
PTC.
divided
according
absence
(group
A—n
=
276)
presence
B—n
107)
interfering
TgAb
first
control
After
follow-up
10
years,
no
structural
detected.
Sixteen
out
three
hundred
eighty-three
(4.2%)
developed
biochemical
events:
12/276
(4.3%)
group
A
4/107
(3.7%)
B.
time
elapsed
from
surgery
detecting
event
14.5
77.5
months
groups
B,
respectively.
No
additional
treatments
followed
up
an
strategy.
Conclusions:
confirmed
that
showed
excellent
outcome
medium
long-term
since
diagnosed.
Significant
variations
Tg/TgAb
few
cases,
all
strategy
need
other
treatments.
Therefore,
relaxed
neck
ultrasound
measurement
enough
early
identify
those
very
unusual
cases
recurrence.
Frontiers in Endocrinology,
Год журнала:
2024,
Номер
15
Опубликована: Ноя. 8, 2024
The
aim
of
this
study
was
to
elucidate
the
relationships
between
thyroid
hormones,
lifestyle
factors,
biochemical
markers,
and
autoimmune
disease
(AITD),
thereby
identifying
factors
influencing
development
these
diseases.
Biomedicines,
Год журнала:
2023,
Номер
12(1), С. 77 - 77
Опубликована: Дек. 28, 2023
In
this
narrative
review,
we
aimed
to
overview
the
interplay
between
lichen
planus
(LP)
and
thyroid
conditions
(TCs)
from
a
dual
perspective
(dermatologic
endocrine),
since
current
gap
in
understanding
LP-TC
connections
is
found
so
far
topic
still
matter
of
debate.
We
searched
PubMed
Inception
October
2023
by
using
key
terms
“lichen
planus”
“thyroid”,
(alternatively,
“endocrine”
or
“hormone”).
included
original
clinical
studies
humans
according
three
sections:
LP
TC
dysfunction,
autoimmunity,
neoplasia.
Six
confirmed
an
association
dysfunction
(exclusively
hypothyroidism)
LP/OL
(oral
LP);
note,
only
one
study
addressed
cutaneous
LP.
The
sample
size
LP/OLP
groups
varied
12–14
1500
individuals.
Hypothyroidism
prevalence
OLP
was
30–50%.
A
higher
rate
levothyroxine
replacement
identified
among
patients,
at
10%
versus
2.5%
controls.
highest
OR
(odd
ratio)
treated
hypothyroidism
amid
2.99
(p
<
0.005).
be
associated
with
milder
phenotype
two
studies.
single
cohort
revealed
similar
non-LP.
Non-confirmatory
(only
on
OLP,
not
LP)
five
cohorts:
controls,
showed
that
subjects
actually
had
lower
controls
(1%
4%).
Positive
autoimmunity
eight
studies;
cohorts
varied,
for
instance,
619
persons
76,
92,
105,
108,
192,
247,
585
patients
(a
total
1405)
respectively;
notably,
largest
control
group
10,441
Four
clusters
approaches
respect
were
found:
analysis
HT/ATD
(Hashimoto’s
thyroiditis/autoimmune
diseases)
prevalence;
considerations
over
specific
antibody
levels;
sex-related
features
females
are
more
prone
autoimmunity;
associations
(if
any)
aspects
LP/OLP.
HT
statistically
significantly
higher,
as
follows:
19%
5%;
12%
6%;
20%
9.8%.
addressing
ATDs.
One
did
confirm
correlation
OLP-associated
elements
(and
severity)
values
against
thyroid,
another
positive
TPOAb
(anti-thyroperoxidase
antibodies)
often
erosive
than
non-erosive
(68%
33%).
Just
reverse,
(9%
15%).
Five
case-control
issue
prior
diagnosed
(no
identified);
them
treatment
(at
8.9%,
9.7%,
10.6%)
conclusion,
regard
LP/OLP-TC,
note
several
main
practical
points
multidisciplinary
practitioners:
rather
requires
awareness;
when
it
comes
type
mostly,
should
expected;
female
ATDs;
potential
ratio
taking
found,
thus
good
collaboration
endocrinology
team
mandatory;
far,
individuals
have
been
risk
nodules/cancer.
COVID-19
emerged
in
December
2019
and
rapidly
became
a
global
pandemic.
It
has
since
been
associated
with
the
progression
of
various
endocrine
disorders,
including
thyroid
disease.
The
long-term
effects
this
interplay
have
yet
to
be
explored.
This
review
explores
relationship
between
diseases,
emphasizing
gland
function
clinical
implications
for
managing
disorders
infected
individuals.
Journal of Translational Autoimmunity,
Год журнала:
2024,
Номер
9, С. 100255 - 100255
Опубликована: Окт. 25, 2024
Since
the
end
of
COVID-19
pandemic,
potential
roles
thyroid-inflammatory
derangements
in
driving
or
being
associated
with
prognosis
remain
controversial.
We
aimed
to
clarify
association
between
infection
and
thyroid
dysfunction,
highlight
impacts
subsequent
autoimmune
disease
(AITD)
on
COVID-19.
American Journal of Case Reports,
Год журнала:
2023,
Номер
25
Опубликована: Дек. 7, 2023
Objective:Rare
coexistence
of
disease
or
pathology
Background:Since
the
COVID-19
pandemic,
several
cases
have
been
linked
to
development
autoimmune
disorders,
including
thyroid.Graves'
(GD)
is
a
rare
complication
that
can
occur
following
SARS-CoV-2
infection.Reports
new
onset
and
exacerbation
GD.We
present
case
42-year-old
woman
with
history
GD
presenting
impending
thyroid
storm
3
weeks
diagnosis
COVID-19.
Case
Report:A
presented
Emergency
Department
(ED)
for
an
acute
hyperthyroidism
after
infection
was
diagnosed
on
home
test.Symptoms
included
daily
headaches,
increased
bilateral
eye
pressure,
fatigue,
muscle
weakness,
episodes
confusion
agitation,
persistent
heart
palpitations,
goiter.Elevated
free
T4
5.57,
T3
15.68,
total
4.43,
near-absent
stimulating
hormone
were
noted.The
Burch-Wartofsky
scale
40,
which
concerning
storm;
however,
at
time
admission,
she
not
in
storm.Treatment
propylthiouracil,
potassium
iodide
oral
solution,
propranolol,
symptom
improvement.Due
prior
intolerance
antithyroid
medications
recent
exacerbation,
thyroidectomy
performed
once
euthyroid
state.
Conclusions:Our
demonstrates
importance
recognizing
as
etiology
trigger
GD.Our
highlights
being
vigilant
recognize
association
between
abnormalities
early
treatment
imperative.
