The Role of Platelet Concentrates and Growth Factors in Facial Rejuvenation: A Systematic Review with Case Series

Medicina, Год журнала: 2025, Номер 61(1), С. 84 - 84

Опубликована: Янв. 7, 2025

Background and objectives: Due to the regeneration potential of growth factors (GFs) platelet concentrates (PCs), facial rejuvenation has been a major area attention in esthetic medicine. The effectiveness safety PCs GFs promoting face are examined this systematic review, which is complemented by case series. essential for collagen production dermal matrix remodeling, while PCs, like Platelet-Rich Plasma (PRP), abundant bioactive chemicals that promote tissue healing cellular regeneration. Materials Methods: A comprehensive literature search was performed on PubMed, Web Science, Scopus, focusing human clinical trials published between February 2019 2024 related PRP esthetics. Results: Thirteen studies met inclusion criteria were analyzed. Conclusions: review summarizes most recent data patient outcomes, treatment regimens, possible hazards. series goes with it shows real-world examples how improve skin elasticity, texture, general appearance little negative side effects. These results highlight use as minimally invasive procedures.

Язык: Английский

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MXene-reinforced bioactive polymer hydrogels for biomedical applications

APL Materials, Год журнала: 2024, Номер 12(8)

Опубликована: Авг. 1, 2024

MXenes, a novel class of two-dimensional (2D) materials, have attracted considerable attention in various fields, especially drug delivery, wound healing, bone tissue engineering, biosensing, and cancer treatment. Thanks to their remarkable physicochemical properties, MXenes hold great promise for biomedical applications. Concurrently, hydrogels composed polymers been extensively utilized contexts. The unique properties facilitate integration into bioactive with enhanced functions thereby endowing the composites multifunctional capabilities. MXene-reinforced polymer (MRPHs) synergistically combine advantageous characteristics both hydrogels, making them highly adaptable other theranostic strategies medical In this comprehensive review, we demonstrate recent advances design synthesis MRPHs Specifically, introduce analyze methods tailoring by incorporating active components, including functional molecules, 2D metal ions, natural polymers, drugs/genes. We then discuss applications designed biosensors, therapy. hope that work provides valuable guidance inspiration readers develop advanced

Язык: Английский

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Conclusion and future prospects of cellulose-based hydrogels

Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 459 - 476

Опубликована: Янв. 1, 2025

Язык: Английский

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Recent advances in nanomaterials and their mechanisms for infected wounds management

Materials Today Bio, Год журнала: 2025, Номер 31, С. 101553 - 101553

Опубликована: Фев. 5, 2025

Wounds infected by bacteria pose a considerable challenge in the field of healthcare, particularly with increasing prevalence antibiotic-resistant pathogens. Traditional antibiotics often fail to achieve effective results due limited penetration, resistance development, and inadequate local concentration at wound sites. These limitations necessitate exploration alternative strategies that can overcome drawbacks conventional therapies. Nanomaterials have emerged as promising solution for tackling bacterial infections facilitating healing, thanks their distinct physicochemical characteristics multifunctional capabilities. This review highlights latest developments nanomaterials demonstrated enhanced antibacterial efficacy improved healing outcomes. The mechanisms are varied, including ion release, chemodynamic therapy, photothermal/photodynamic electrostatic interactions, delivery drugs, which not only combat but also address challenges posed biofilms antibiotic resistance. Furthermore, these create an optimal environment tissue regeneration, promoting faster closure. By leveraging unique attributes nanomaterials, there is significant opportunity revolutionize management wounds markedly improve patient

Язык: Английский

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Enhanced printability of high-viscosity chitosan/acrylamide inks via aluminum ions coordination for precision 3D bioprinting of scaffolds

Carbohydrate Polymers, Год журнала: 2025, Номер 355, С. 123359 - 123359

Опубликована: Фев. 5, 2025

Язык: Английский

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Bioactive hemostatic materials: a new strategy for promoting wound healing and tissue regeneration

MedComm, Год журнала: 2025, Номер 6(4)

Опубликована: Март 22, 2025

Abstract Wound healing remains a critical global healthcare challenge, with an annual treatment cost exceeding $50 billion worldwide. Over the past decade, significant advances in wound care have focused on developing sophisticated biomaterials that promote tissue regeneration and prevent complications. Despite these developments, there crucial need for multifunctional materials can effectively address complex, multiphase nature of repair while being effective easily applicable various clinical settings. This review systematically analyzes latest developments materials, examining their chemical composition, structural design, therapeutic mechanisms. We comprehensively evaluate bioactive components, including natural polymers, synthetic matrices, hybrid composites, along different forms, such as hydrogels, powders, smart dressings. Special attention is given to emerging strategies material design integrate multiple functions, sustained drug delivery, infection prevention, promotion. The insights provided this illuminate path toward next‐generation highlighting opportunities more solutions significantly improve patient outcomes reduce burden.

Язык: Английский

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4D Bioprinting for Personalized Medicine, Innovations in Implant Fabrication and Regenerative Therapies

Polymer-Plastics Technology and Materials, Год журнала: 2025, Номер unknown, С. 1 - 26

Опубликована: Март 30, 2025

Язык: Английский

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Nature-Inspired Healing: Biomimetic Nanomaterials for Advanced Wound Management

Materials Today Sustainability, Год журнала: 2024, Номер 28, С. 100975 - 100975

Опубликована: Сен. 6, 2024

Язык: Английский

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Wound Closure Promotion by Leucine-Based Pseudo-Proteins: An In Vitro Study

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(17), С. 9641 - 9641

Опубликована: Сен. 6, 2024

Our research explores leucine-based pseudo-proteins (LPPs) for advanced wound dressings, focusing on their effects healing in an vitro model. We assessed three types of LPP films ability to enhance closure rates and modulate cytokine production. They all significantly improved compared traditional methods, with the 8L6 copolymer showing most pronounced effects. Notably, latter exhibited optimal profile: initial burst pro-inflammatory TNF-α, followed by a controlled release IL-6 during proliferative phase significant increase anti-inflammatory IL-10 remodeling. This balanced response suggests that film not only accelerates but also supports well-regulated process, potentially reducing fibrosis abnormal scarring, underscoring potential LPPs as dressing materials. Future will aim elucidate specific signaling pathways activated better understand its mechanism action. Overall, offer promising approach improving care could lead more effective treatments complex wounds.

Язык: Английский

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Estructuras tipo origami en el desarrollo de biomateriales inteligentes a partir de impresión 4D

PÄDI Boletín Científico de Ciencias Básicas e Ingenierías del ICBI, Год журнала: 2024, Номер 12, С. 224 - 232

Опубликована: Дек. 13, 2024

La manufactura aditiva tiene un gran potencial en el campo de los biomateriales por su capacidad para desarrollar diseños intrincados y complejos. Este estudio presenta una revisión sobre papel la creación estructuras tipo origami inteligentes a partir biopolímeros con respuesta ante estímulos externos (impresión 4D). Desde década 1990, ingeniería tejidos ha dependido medida andamios, siendo punto clave promover adhesión celular, proliferación diferenciación, integrando biología celular ciencia materiales. impresión 4D constituye solución las limitaciones andamios convencionales. Esta tecnología innovadora permite integración origami, cambio forma como estímulos, lo cual incrementa crear dinámicos, plegables receptivos, abriendo nuevas vías medicina regenerativa.

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