Functionalized borophene with methylene blue tagging for sensitive electrochemical detection of PFOA

Materials Science and Engineering B, Год журнала: 2025, Номер 314, С. 118073 - 118073

Опубликована: Фев. 3, 2025

Язык: Английский

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Label-Free Liquid Crystal Biosensor Based on Split Aptamers for Detecting Serum Myoglobin

Langmuir, Год журнала: 2025, Номер unknown

Опубликована: Фев. 17, 2025

Myoglobin (Mb) is a critical cytoplasmic heme protein and one of the earliest detectable biomarkers following acute myocardial infarction (MI). The rapid precise detection serum Mb holds significant clinical value. This study capitalizes on advantages split aptamer (Apt) sequence, which short effectively minimizes false-positive signals caused by secondary structure probe. It constructs "sandwich"-structured liquid crystal biosensor with an "Apt-target molecule-Apt" configuration for label-free Mb. Apt fragments were immobilized surface glass substrate as capture probes (CP) using triethoxybutanal silane (TEA) linker molecules. When present, other fragment, signal probe (SP), specifically binds reassociates CP, restoring original stem-loop Apt, thereby inducing change in alignment 5CB leads to variations brightness color optical polarizing microscope image, facilitating quantitative method capable detecting concentrations ranging from 0.05 130 ng/mL, minimum limit 0.045 ng/mL. sandwich biosensing offers several advantages, including detection, operational simplicity, high specificity. demonstrates potential biomarkers.

Язык: Английский

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A Hydrothermal and Combustion-Reduction Process with Polyvinyl Pyrrolidone as a Restricted Growth Agent and Galactose as a Reducing Agent for the Fabrication of Rod-like α-Fe2O3/Fe3O4 Magnetic Nanocomposites

Materials, Год журнала: 2025, Номер 18(5), С. 1014 - 1014

Опубликована: Фев. 25, 2025

A hydrothermal and combustion-reduction process with polyvinyl pyrrolidone (PVP) as a restricted growth agent galactose reducing was developed for the fabrication of rod-like α-Fe2O3/Fe3O4 magnetic nanocomposites (MNCs). Firstly, β-FeOOH nanorods (NRs) were fabricated by method, PVP agent. To obtain smaller size better applications in biomedical field, concentrations FeCl3 PVP, temperature, time optimized 0.171 M, 0.163 mM, 100 °C, 8 h, NRs 193.1 nm average length 43.2 diameter. Then, precursors, MNCs prepared via agent; factors calcination temperature mass ratio assessed 300 0.5 1:2, respectively. The under conditions 81.6 23.9 diameter, while their saturation magnetization reached 69.8 emu/g.

Язык: Английский

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Electrochemical biosensors for early detection of Alzheimer’s disease

Clinica Chimica Acta, Год журнала: 2025, Номер unknown, С. 120278 - 120278

Опубликована: Апрель 1, 2025

Язык: Английский

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