A Bifunctional Fluorescence Probe for the Detection of Hypochlorous Acid and Viscosity in Living Cells and Zebrafish DOI Creative Commons
Xin Zhang, Yanmei Si, Xinpeng Chen

и другие.

Molecules, Год журнала: 2025, Номер 30(7), С. 1531 - 1531

Опубликована: Март 30, 2025

As two significant indicators in the microenvironment, hypochlorous acid and viscosity play important roles multitudinous physiological metabolic processes. However, it is challenging to determine dynamic levels of living cells organisms because absence effective molecular tools that can simultaneously detect organisms. Herein, a design strategy was presented fabricate single fluorescence probe by using different emission channels. In JXR, TICT-based 4-(2-(5-(dimethylamino)thiophen-2-yl)vinyl)-1-methylpyridin-1-ium-iodide chromophore serves as energy acceptor FRET process sensors for viscosity. JXR showed large Stokes shift, wide peak distance, high photostability, low toxicity. could rapidly, sensitively, selectively emitting signals. Importantly, successfully applied track intracellular cells. Meanwhile, generation endogenous hypochlorite be observed JXR.

Язык: Английский

Design and development of a bright NIR fluorescent probe for selective HSA detection in human blood serum and urine DOI
Arindam Mondal, Subrata Dutta

Bioorganic Chemistry, Год журнала: 2025, Номер 159, С. 108356 - 108356

Опубликована: Март 7, 2025

Язык: Английский

Процитировано

0
A Bifunctional Fluorescence Probe for the Detection of Hypochlorous Acid and Viscosity in Living Cells and Zebrafish DOI Creative Commons
Xin Zhang, Yanmei Si, Xinpeng Chen

и другие.

Molecules, Год журнала: 2025, Номер 30(7), С. 1531 - 1531

Опубликована: Март 30, 2025

As two significant indicators in the microenvironment, hypochlorous acid and viscosity play important roles multitudinous physiological metabolic processes. However, it is challenging to determine dynamic levels of living cells organisms because absence effective molecular tools that can simultaneously detect organisms. Herein, a design strategy was presented fabricate single fluorescence probe by using different emission channels. In JXR, TICT-based 4-(2-(5-(dimethylamino)thiophen-2-yl)vinyl)-1-methylpyridin-1-ium-iodide chromophore serves as energy acceptor FRET process sensors for viscosity. JXR showed large Stokes shift, wide peak distance, high photostability, low toxicity. could rapidly, sensitively, selectively emitting signals. Importantly, successfully applied track intracellular cells. Meanwhile, generation endogenous hypochlorite be observed JXR.

Язык: Английский

Процитировано

0