Food Science and Biotechnology, Год журнала: 2023, Номер 33(7), С. 1685 - 1696
Опубликована: Ноя. 28, 2023
Язык: Английский
Food Science and Biotechnology, Год журнала: 2023, Номер 33(7), С. 1685 - 1696
Опубликована: Ноя. 28, 2023
Язык: Английский
Contrast Media & Molecular Imaging, Год журнала: 2022, Номер 2022(1)
Опубликована: Янв. 1, 2022
Chronic obstructive pulmonary disease (COPD) is a major and difficult of the chronic respiratory system that common frequent, with huge burden. The aim this study was to investigate efficacy safety budesonide/glyburide/formoterol fumarate (BGF) in treatment COPD.A comprehensive literature search conducted PubMed, Embase, Cochrane Library, Web Science. basic features seven pieces were identified using strategy. sample size range 130∼1264.The effects BGF increased FEV1 patients COPD (mean difference = 2.86, 95%CI: 2.71-3.01, p < 0.00001). improved ≥1 TEAE COPD, not statistically significant after (Odds rate 1.00, 0.85-1.17, p=0.97). TEAEs related (odds 1.27, 95% CI: 1.03-1.57, p=0.02). decreased serious -0.02, -0.03--0.00, p=0.04). death 0.77, 0.31-1.97, p=0.59). hypertension 0.92, 0.44-1.89, p=0.81), treatment. pneumonia 1.55, 0.81-2.97, p=0.19), FEV1, treatment, COPD.This elucidates view providing clinical reference.
Язык: Английский
Процитировано
2Frontiers in Pharmacology, Год журнала: 2023, Номер 14
Опубликована: Март 14, 2023
Introduction: Pharbitidis Semen (PS) has been widely used in traditional Chinese medicine to treat several diseases such as nephritis. PS is usually stir-fried enhance its therapeutic efficacy before use clinical practice. However, the changes phenolic acids during stir-frying and mechanisms of their effects on nephritis are still unclear. Methods: Here, we studied processing-induced chemical elucidated mechanism treatment We determined levels 7 raw (RPS) (SPS) using high-performance liquid chromatography, analyzed dynamic compositional stir-frying, network analysis molecular docking predict verify compound targets pathways corresponding Results: The suggestive a transesterification reaction. Pathway revealed that were mainly enriched AGE-RAGE, hypoxia-inducible factor-1, interleukin-17, tumor necrosis factor signaling among others. Molecular results showed had good binding ability with key nephritic targets. Discussion: potential pharmaceutical basis, targets, treating explored. Our findings provide scientific basis for
Язык: Английский
Процитировано
0SVOA Dentistry, Год журнала: 2023, Номер 4(3), С. 102 - 109
Опубликована: Май 31, 2023
Tobacco use is one of the major causes mortality due to non-communicable diseases. The chemicals present in tobacco affect almost all parts body and cause various Although majority users are aware about ill effects tobacco, they unable quit because presence highly addictive substance nicotine. experience withdrawal symptoms their attempt which further discourages them from quitting. Despite fact that Nicotine replacement therapy (NRT) found be effective, it associated with several side effects. Natural products or herbal remedies safer alternatives NRT. Numerous herbs antioxidant antianxiety properties have been tried combat nicotine thereby facilitate cessation. Alternative therapies those easily available, fewer can used reduce burden world. In this review, we enlisted for cessation medicinal on tobacco.
Язык: Английский
Процитировано
0Food Science and Biotechnology, Год журнала: 2023, Номер 33(7), С. 1685 - 1696
Опубликована: Ноя. 28, 2023
Язык: Английский
Процитировано
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