Pharmaceuticals,
Год журнала:
2024,
Номер
17(5), С. 636 - 636
Опубликована: Май 15, 2024
Astragalus
polysaccharide
(APS)
derived
from
A.
membranaceus
plays
a
crucial
role
in
traditional
Chinese
medicine.
These
polysaccharides
have
shown
antitumor
effects
and
are
considered
safe.
Thus,
they
become
increasingly
important
cancer
immunotherapy.
APS
can
limit
the
spread
of
by
influencing
immune
cells,
promoting
cell
death,
triggering
autophagy,
impacting
tumor
microenvironment.
When
used
combination
with
other
therapies,
enhance
treatment
outcomes
reduce
toxicity
side
effects.
combined
checkpoint
inhibitors,
relay
cellular
immunotherapy,
vaccines
broadened
application
immunotherapy
enhanced
effectiveness.
By
summarizing
research
on
over
past
two
decades,
this
review
elaborates
anticancer
mechanism
its
use
clinical
trials.
Considering
multiple
roles
APS,
emphasizes
importance
using
as
an
adjunct
to
compares
APS.
This
discussion
provides
insights
into
specific
action
reveals
molecular
targets
for
developing
effective
strategies,
highlights
wide
therapy
future.
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Апрель 10, 2024
Type
2
diabetes
presents
a
significant
global
health
burden
and
is
frequently
linked
to
serious
clinical
complications,
including
diabetic
cardiomyopathy,
nephropathy,
retinopathy.
Astragalus
polysaccharide
(APS),
extracted
from
