Current views and trends of nanomaterials as vectors for gene delivery since the 21st century: a bibliometric analysis

Nanomedicine, Год журнала: 2025, Номер unknown, С. 1 - 16

Опубликована: Янв. 29, 2025

Gene therapy is garnering increasing support due to its potential for a "once-delivered, lifelong benefit." The limitations of traditional gene delivery methods have spurred the advancement bionanomaterials. Despite this progress, thorough analysis evolution, current state, key contributors, focal studies, and future directions nanomaterials in remains absent. This study scrutinizes articles from Web Science, spanning 1 January 2 000, 31 December 2023, employing various online tools visualization. 21st century has witnessed consistent growth scholarly work domain globally, with notable contributions China US. At same time, Chinese Academy Sciences (CAS), Harvard University, Massachusetts Institute Technology (MIT) emerged as most productive institutions, CAS's academician Weihong Tan becoming field's leading author. While drug nanoparticles (NPs) been central themes two decades, research focus shifted modifying NPs ultrafine particles exploring polymer-hybrid NPs, mRNA vaccines, immune responses, green synthesis, CRISPR/Cas tools. shift marks transition insights provided by offer comprehensive overview field valuable guidance investigations.

Язык: Английский

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Nanotechnology Assisted Strategies to Tackle COVID and Long-COVID

BioNanoScience, Год журнала: 2025, Номер 15(2)

Опубликована: Фев. 4, 2025

Язык: Английский

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Cutting-edge progress in the protective efficacy of nanovaccines against poultry diseases

World s Poultry Science Journal, Год журнала: 2025, Номер unknown, С. 1 - 23

Опубликована: Фев. 5, 2025

Язык: Английский

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Nanoparticles as an Alternative Strategy to Control Foot and Mouth Disease Virus in Bovines

Biological Trace Element Research, Год журнала: 2025, Номер unknown

Опубликована: Фев. 7, 2025

Язык: Английский

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Unveiling the Threat of Disease X: Preparing for the Next Global Pandemic

Journal of Medical Virology, Год журнала: 2025, Номер 97(2)

Опубликована: Фев. 1, 2025

ABSTRACT The term “Disease X”, first introduced by the World Health Organization (WHO) in 2018, symbolizes threat of an unknown pathogen capable causing a global pandemic. Classified as “priority pathogens,” Disease X stands alongside well‐known threats like SARS, Ebola, and ZIKV due to its potential for widespread outbreaks. SARS‐CoV‐2 is considered X” fulfill this prediction, demonstrating devastating impact such pathogens can have. A future could pose even greater threat, with catastrophic consequences. This paper examines origins pathogens, drawing lessons from outbreaks MERS, SARS‐CoV‐2. It also highlights strategic approaches detect, prevent, respond effectively mitigate risk pandemics.

Язык: Английский

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Nanoscience in Action: Unveiling Emerging Trends in Materials and Applications

ACS Omega, Год журнала: 2025, Номер unknown

Опубликована: Фев. 17, 2025

Since their inception in the early 1960s, use of nanoscale materials has progressed leaps and bounds, role diverse fields ranging from human health to energy is undeniable. In this report, we utilize CAS Content Collection, a vast repository scientific information extracted journals patent publications, identify emerging topics field. This involves understanding trends, such as growth certain over time, well establishing relationships among topics. We achieved by using host strategies including quantitative natural language processing (NLP) approach 270 subtopics across three major categories-materials, applications, properties-by surveying 3 million documents spanning two decades nanoscience landscape. wealth been condensed into several conceptual Trendscape maps other data visualizations, providing metrics related identified concepts, grouped hierarchical classes, connections between them have explored. Our extensive analysis taking advantage an NLP-based along with robust indexing provides valuable insights field that hope can help inform drive future research efforts. series interconnected papers, will present our findings project, focus on four applications materials-drug delivery, sensors, energy, catalysis-to provide more comprehensive detailed picture nanotechnology these fields.

Язык: Английский

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Helicobacter pylori and gastric cancer: current insights and nanoparticle-based interventions

RSC Advances, Год журнала: 2025, Номер 15(7), С. 5558 - 5570

Опубликована: Янв. 1, 2025

Background: H. pylori is recognized as one of the main causes gastric cancer, and this type cancer considered leading diseases causing deaths all over world.

Язык: Английский

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Urgent Focus on the Surgical Risks of People Living With HIV: A Systematic Review and Meta‐Analysis

Journal of Medical Virology, Год журнала: 2025, Номер 97(2)

Опубликована: Фев. 1, 2025

ABSTRACT With the widespread promotion and application of antiretroviral therapy in clinical practice, people living with HIV (PLWH) have potential to live as long non‐HIV probability surgery for PLWH has been increasing dramatically. However, overall postoperative outcome risk are still unclear. We performed comprehensive methodical searches PubMed, Embase, Web Science without date language restrictions. Study outcomes included: (1) cure rate, (2) mortality, (3) reoperation (4) incidence any complications, (5) length stay, (6) operation duration. NOS scores were employed evaluate bias risk, while publication was assessed using funnel plots Egger tests. Review Manager version 5.4.1, R 4.4.1, Stata 14.0 determine quantitative analysis, considering a significance level p < 0.05. A total 50 studies included, involving 54 565 undergoing surgical treatment. Synthesis analysis showed that mortality (OR = 1.70, 95% CI: 1.58−1.83, 0.00001), rate 1.78, 1.36−2.34, complication 1.56, 1.26−1.95, LOS 1.63, 1.28−1.99, time 7.37, 1.14−13.59, 0.02) increased PLWH. there no significant difference compared control group 1.27, 0.90−1.79, 0.18). Subgroup rates again orthopedic 1.65, 1.34−2.05, 0.00001) general 1.72, 1.08−2.74, 0.02). type procedure, quality, study type, patient origin not sources heterogeneity. Meta‐regression CD4 count had effect on but anti‐retroviral 34.89% explanatory power. There is an death, reoperation, prolonged hospital stay duration conducting extensive prospective across multiple centers crucial validate these findings.

Язык: Английский

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Contribution of Microbial Nanotechnology to Sustainable Development Goals

Опубликована: Янв. 1, 2025

Язык: Английский

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Genetic and Molecular Profiling in Merkel Cell Carcinoma: Focus on MCPyV Oncoproteins and Emerging Diagnostic Techniques

Pathology - Research and Practice, Год журнала: 2025, Номер unknown, С. 155869 - 155869

Опубликована: Фев. 1, 2025

Язык: Английский

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