“Aging Amplifies Challenges”: A Descriptive Phenomenological Exploration of the Lived Experiences and Needs of Elderly Individuals With Schizophrenia
Nursing and Health Sciences,
Год журнала:
2024,
Номер
26(4)
Опубликована: Окт. 9, 2024
Older
adults
diagnosed
with
schizophrenia
face
unique
public
health
challenges,
specific
treatment
needs,
complex
care
demands,
accelerated
aging,
and
increased
susceptibility
to
issues.
This
phenomenological
study
explored
the
existential
realities
needs
of
older
schizophrenia.
Fifteen
participants,
a
mean
age
69.47
(SD
±
9.47)
years,
ranging
from
62
79
years
old
hailing
rural
regions,
participated
in
study.
Four
main
themes
eight
sub-themes
emerge:
compounding
burden
(challenges
symptom
management,
comorbidities);
abyss
life
filled
emptiness
(loss
mental
pillars,
living
agony);
on
margins
society
(the
vicious
cycle
social
self-isolation,
unattainable
welfare);
glimmer
light
darkness
(support
systems,
self-adjustment).
The
calls
for
healthcare
professionals
improve
follow-up
efficiency,
strengthen
engagement,
understand
patients'
conditions
enforce
existing
welfare
policies
mentally
ill
patients,
enhance
their
quality
life.
Язык: Английский
‘Whole-Body’ Perspectives of Schizophrenia and Related Psychotic Illness: miRNA-143 as an Exemplary Molecule Implicated across Multi-System Dysfunctions
Biomolecules,
Год журнала:
2024,
Номер
14(9), С. 1185 - 1185
Опубликована: Сен. 20, 2024
A
wide
array
of
biological
abnormalities
in
psychotic
illness
appear
to
reflect
non-cerebral
involvement.
This
review
first
outlines
the
evidence
for
such
a
whole-body
concept
schizophrenia
pathobiology,
focusing
particularly
on
cardiovascular
disease,
metabolic
syndrome
and
diabetes,
immunity
inflammation,
cancer,
gut–brain
axis.
It
then
considers
roles
miRNAs
general
miRNA-143
particular
as
they
relate
epidemiology,
treatment
schizophrenia.
is
followed
by
notable
that
also
implicated
each
these
domains
Thus,
an
exemplar
what
may
be
class
molecules
play
role
across
multiple
bodily
dysfunction
characterize
perspective
Importantly,
existence
exemplary
molecule
implies
coordinated
rather
than
stochastic
basis.
One
candidate
process
would
pleiotropic
effect
genetic
risk
whole
body.
Язык: Английский