Investigation on the potential application of kaemperide in hyperuricemia based on kidney-on-a-chip DOI
Xinyu Song, Lili Zhao, Yingying Tian

и другие.

Lab on a Chip, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Hyperuricemia (HUA), a serious metabolic disease that manifests as an elevated serum uric acid (SUA) level, is closely related to gout, hypertension, diabetes, coronary heart disease, chronic kidney and other conditions.

Язык: Английский

An overview of graphene-based sensors for organ-on-a-chip systems DOI
Lionel J. Ouedraogo, McKayla Kling, Nicole N. Hashemi

и другие.

Innovation and Emerging Technologies, Год журнала: 2025, Номер 12

Опубликована: Янв. 1, 2025

This literature review provides a concise overview of graphene-based sensors and their diverse applications. Various types graphene working principles are discussed, including field-effect transistors (FETs), resistive sensors, optical electrochemical surface-enhanced Raman spectroscopy (SERS) strain thermal sensors. Each sensor type is described with relevant examples potential The highlights significant advancements in such as healthcare applications DNA sequencing disease biomarker detection, real-time monitoring air pollutants water quality assessment, integration into wearable devices for vital sign gesture recognition, role energy harvesting systems. advantages exceptional sensitivity, rapid response time, wide analyte detection range, compatibility different substrates, discussed. However, challenges large-scale fabrication, sensitivity to environmental factors, sensor-to-sensor variability persist. Additionally, the delves organ-on-a-chip (OOC) systems, microphysiological platforms that mimic human organs’ structure function. OOC physiologically drug discovery, modeling, personalized medicine, toxicity testing, highlighted. limitations traditional vitro vivo models leading systems address these limitations. biosensors, electrodes, scaffolds, barriers, membranes examined, showcasing its contributions enhanced functionality physiological relevance. Overall, offer promising avenues advanced sensing, medicine.

Язык: Английский

Процитировано

0

Advances in Cellular and Molecular Biology Assays: A Review of Gold Standard Methods DOI

Katiana Simões Lopes Kittelson,

Allana Cristina Faustino Martins,

Gizele Celante

и другие.

Опубликована: Апрель 30, 2025

Considering the number of available methods in molecular and cellular biology rapid development new technologies, need for an updated guide on what is currently applied how to choose best method a specific goal has increased. Gold standard are known their accuracy reliable data under certain circumstances, allowing replicability. This perspective aims characterize define current gold techniques from last five years, enlighten historical background, cite drawbacks benefits, delimit possible future aspects.

Язык: Английский

Процитировано

0

Emerging Trends in Microfluidic Biomaterials: From Functional Design to Applications DOI Creative Commons

Lin Jiaqi,

Lijuan Cui,

Xiaokun Shi

и другие.

Journal of Functional Biomaterials, Год журнала: 2025, Номер 16(5), С. 166 - 166

Опубликована: Май 8, 2025

The rapid development of microfluidics has driven innovations in material engineering, particularly through its ability to precisely manipulate fluids and cells at microscopic scales. Microfluidic biomaterials, a cutting-edge interdisciplinary field integrating microfluidic technology with biomaterials science, are revolutionizing biomedical research. This review focuses on the functional design fabrication organ-on-a-chip (OoAC) platforms via 3D bioprinting, explores applications drug delivery, cell culture, tissue evaluates potential systems advancing personalized healthcare. We systematically analyze evolution materials—from silicon glass polymers paper—and highlight advantages bioprinting over traditional methods. Currently, despite significant advances medicine, challenges scalability, stability, clinical translation remain. future will depend combining dynamic design, developing hybrid strategies that combine molds bio-printed structures, using artificial intelligence monitor delivery or response real time. believe collaborations between materials micromachining, medicine accelerate into therapies high-throughput screening tools.

Язык: Английский

Процитировано

0

A low-cost multi-layer microfluidic platform for on-site viability assessment of stem cells at single-cell resolution DOI
Wenjie Xiao, Jiahao Guo, Xusheng Zhao

и другие.

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113948 - 113948

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Investigation on the potential application of kaemperide in hyperuricemia based on kidney-on-a-chip DOI
Xinyu Song, Lili Zhao, Yingying Tian

и другие.

Lab on a Chip, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Hyperuricemia (HUA), a serious metabolic disease that manifests as an elevated serum uric acid (SUA) level, is closely related to gout, hypertension, diabetes, coronary heart disease, chronic kidney and other conditions.

Язык: Английский

Процитировано

0