Hyperuricemia
(HUA),
a
serious
metabolic
disease
that
manifests
as
an
elevated
serum
uric
acid
(SUA)
level,
is
closely
related
to
gout,
hypertension,
diabetes,
coronary
heart
disease,
chronic
kidney
and
other
conditions.
Innovation and Emerging Technologies,
Год журнала:
2025,
Номер
12
Опубликована: Янв. 1, 2025
This
literature
review
provides
a
concise
overview
of
graphene-based
sensors
and
their
diverse
applications.
Various
types
graphene
working
principles
are
discussed,
including
field-effect
transistors
(FETs),
resistive
sensors,
optical
electrochemical
surface-enhanced
Raman
spectroscopy
(SERS)
strain
thermal
sensors.
Each
sensor
type
is
described
with
relevant
examples
potential
The
highlights
significant
advancements
in
such
as
healthcare
applications
DNA
sequencing
disease
biomarker
detection,
real-time
monitoring
air
pollutants
water
quality
assessment,
integration
into
wearable
devices
for
vital
sign
gesture
recognition,
role
energy
harvesting
systems.
advantages
exceptional
sensitivity,
rapid
response
time,
wide
analyte
detection
range,
compatibility
different
substrates,
discussed.
However,
challenges
large-scale
fabrication,
sensitivity
to
environmental
factors,
sensor-to-sensor
variability
persist.
Additionally,
the
delves
organ-on-a-chip
(OOC)
systems,
microphysiological
platforms
that
mimic
human
organs’
structure
function.
OOC
physiologically
drug
discovery,
modeling,
personalized
medicine,
toxicity
testing,
highlighted.
limitations
traditional
vitro
vivo
models
leading
systems
address
these
limitations.
biosensors,
electrodes,
scaffolds,
barriers,
membranes
examined,
showcasing
its
contributions
enhanced
functionality
physiological
relevance.
Overall,
offer
promising
avenues
advanced
sensing,
medicine.
Considering
the
number
of
available
methods
in
molecular
and
cellular
biology
rapid
development
new
technologies,
need
for
an
updated
guide
on
what
is
currently
applied
how
to
choose
best
method
a
specific
goal
has
increased.
Gold
standard
are
known
their
accuracy
reliable
data
under
certain
circumstances,
allowing
replicability.
This
perspective
aims
characterize
define
current
gold
techniques
from
last
five
years,
enlighten
historical
background,
cite
drawbacks
benefits,
delimit
possible
future
aspects.
Journal of Functional Biomaterials,
Год журнала:
2025,
Номер
16(5), С. 166 - 166
Опубликована: Май 8, 2025
The
rapid
development
of
microfluidics
has
driven
innovations
in
material
engineering,
particularly
through
its
ability
to
precisely
manipulate
fluids
and
cells
at
microscopic
scales.
Microfluidic
biomaterials,
a
cutting-edge
interdisciplinary
field
integrating
microfluidic
technology
with
biomaterials
science,
are
revolutionizing
biomedical
research.
This
review
focuses
on
the
functional
design
fabrication
organ-on-a-chip
(OoAC)
platforms
via
3D
bioprinting,
explores
applications
drug
delivery,
cell
culture,
tissue
evaluates
potential
systems
advancing
personalized
healthcare.
We
systematically
analyze
evolution
materials—from
silicon
glass
polymers
paper—and
highlight
advantages
bioprinting
over
traditional
methods.
Currently,
despite
significant
advances
medicine,
challenges
scalability,
stability,
clinical
translation
remain.
future
will
depend
combining
dynamic
design,
developing
hybrid
strategies
that
combine
molds
bio-printed
structures,
using
artificial
intelligence
monitor
delivery
or
response
real
time.
believe
collaborations
between
materials
micromachining,
medicine
accelerate
into
therapies
high-throughput
screening
tools.
Hyperuricemia
(HUA),
a
serious
metabolic
disease
that
manifests
as
an
elevated
serum
uric
acid
(SUA)
level,
is
closely
related
to
gout,
hypertension,
diabetes,
coronary
heart
disease,
chronic
kidney
and
other
conditions.