A Survey of theDesulfuromonadiacytochromome provides a glimpse of the unexplored diversity of multiheme cytochromes in nature DOI Creative Commons
Ricardo Soares, Bruno M. Fonseca, Benjamin W. Nash

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Янв. 6, 2024

Abstract Multiheme cytochromes (MHC) provide prokaryotes with a broad metabolic versatility that contributes to their role in the biogeochemical cycling of elements. However, MHC were isolated and studied detail only from limited number species. To obtain broader view diversity MHC, we employed bioinformatics tools study cytochromome encoded genomes Desulfuromonadia class. We found predicted be extracellular are least conserved present higher diversity. Although most prevalent have homologues already characterized, nearly half families Desulforomonadia class no known AlphaFold2 was predict 3D structures. This work illuminates for first time universe experimentally uncharacterized likely contribute fitness diverse environmental conditions drive biotechnological applications.

Язык: Английский

A Survey of theDesulfuromonadiacytochromome provides a glimpse of the unexplored diversity of multiheme cytochromes in nature DOI Creative Commons
Ricardo Soares, Bruno M. Fonseca, Benjamin W. Nash

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Янв. 6, 2024

Abstract Multiheme cytochromes (MHC) provide prokaryotes with a broad metabolic versatility that contributes to their role in the biogeochemical cycling of elements. However, MHC were isolated and studied detail only from limited number species. To obtain broader view diversity MHC, we employed bioinformatics tools study cytochromome encoded genomes Desulfuromonadia class. We found predicted be extracellular are least conserved present higher diversity. Although most prevalent have homologues already characterized, nearly half families Desulforomonadia class no known AlphaFold2 was predict 3D structures. This work illuminates for first time universe experimentally uncharacterized likely contribute fitness diverse environmental conditions drive biotechnological applications.

Язык: Английский

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