Recently,
flexible
electronics
have
significantly
transformed
information
and
communications
technology
(ICT).
In
particular,
wearable
devices,
via
integration
with
attachable
biosensors,
driven
the
development
of
new
types
biosensors
diagnostic
devices
for
point-of-care
testing
(POCT).
Moreover,
electrochemical
can
be
applied
to
diagnose
diseases
in
real
time
based
on
synergistic
effect
generated
from
incorporation
technique.
Besides,
improve
sensitivity
while
retaining
their
wearability,
novel
nanomaterials
nanotechnologies
been
introduced.
this
review,
recent
studies
nanotechnology-based
accurate
disease
diagnosis
are
discussed.
First,
widely
used
techniques
developing
electrodes,
including
nanolithography-
nano/microneedle-based
patches,
presented.
Next,
latest
such
as
diabetes
dermatitis
discussed
by
categorizing
into
categories.
Finally,
review
explores
research
trends
application
nanotechnology-enabled
nanopatterning
nano/microneedle
technologies
biosensors.
This
suggests
approaches
methods
real-time
under
POCT
applications.
Biosensors,
Год журнала:
2024,
Номер
14(11), С. 560 - 560
Опубликована: Ноя. 18, 2024
Wearable
biosensors
are
a
fast-evolving
topic
at
the
intersection
of
healthcare,
technology,
and
personalized
medicine.
These
sensors,
which
frequently
integrated
into
clothes
accessories
or
directly
applied
to
skin,
provide
continuous,
real-time
monitoring
physiological
biochemical
parameters
such
as
heart
rate,
glucose
levels,
hydration
status.
Recent
breakthroughs
in
downsizing,
materials
science,
wireless
communication
have
greatly
improved
functionality,
comfort,
accessibility
wearable
biosensors.
This
review
examines
present
status
biosensor
with
an
emphasis
on
advances
sensor
design,
fabrication
techniques,
data
analysis
algorithms.
We
analyze
diverse
applications
clinical
diagnostics,
chronic
illness
management,
fitness
tracking,
emphasizing
their
capacity
transform
health
facilitate
early
disease
diagnosis.
Additionally,
this
seeks
shed
light
future
healthcare
wellness
by
summarizing
existing
trends
new
advancements.
Sensors,
Год журнала:
2025,
Номер
25(4), С. 1045 - 1045
Опубликована: Фев. 10, 2025
Lactate
is
a
key
metabolite
in
cellular
respiration,
and
elevated
levels
usually
indicate
tissue
hypoxia
or
metabolic
dysregulation.
The
real-time
detection
of
lactate
particularly
important
situations
such
as
exercise,
shock,
severe
trauma,
injury.
Conventional
assays
are
insufficient
to
address
today’s
complex
variable
testing
environments,
thus,
there
an
urgent
need
for
highly
sensitive
biosensors.
This
review
article
provides
overview
the
concept
composition
electrochemical
biosensors,
well
their
recent
advances.
Comparisons
popular
studies
on
enzymatic
non-enzymatic
sensors,
surface-related
materials
used
modifications
methods
commonly
sensors
discussed
separately.
In
addition,
advances
implantable
non-implantable
miniaturized
discussed,
emphasizing
application
continuous
monitoring.
Despite
potential,
challenges
non-specific
binding,
biomaterial
interference,
biorecognition
element
stability
issues
remain
during
practical
applications.
Future
research
should
aim
improve
sensor
design,
biocompatibility,
integration
with
advanced
signal
processing
techniques.
With
continued
innovation,
expected
revolutionize
personalized
medicine,
helping
clinicians
increase
treatment
efficiency
experience
use.
IntechOpen eBooks,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 27, 2025
Microneedles
(MNs)
have
been
used
as
active
drug
delivery
carriers
by
precisely
delivering
drugs
to
the
targeted
site
along
with
minimal
tissue
destruction.
Earlier,
MNs
were
for
of
transdermal
site;
now
they
are
solid
tumor
site,
mucosal,
ophthalmic,
and
other
organ
site-specific
delivery.
considered
a
boon
trans-barrier
because
routes,
such
systemic
parenteral,
face
challenges
limiting
optimum
amount
reaching
skin
or
barrier-containing
organs.
Hence,
MN-mediated
enhances
permeation
improves
brain
ciliary
nasal
clearance
crossing
barrier.
The
current
book
chapter
mainly
focuses
on
recent
advancements
in
area
MN-based
into
various
parts
body,
their
theragnostic
applications,
organs
containing
barriers,
encounters
has
discussed.
Also,
comprehensive
overview
MN
types,
fabrication
polymers,
mechanisms
release,
effectiveness,
advantages
over
conventional
systems
summarized.
Chemosensors,
Год журнала:
2025,
Номер
13(2), С. 32 - 32
Опубликована: Янв. 24, 2025
Monitoring
of
immune
factors,
including
interferon-gamma
(IFN-γ),
holds
great
importance
for
understanding
responses
and
disease
diagnosis.
Wearable
sensors
enable
continuous
non-invasive
detection
markers
in
sweat,
drawing
significant
attention
to
their
potential
real-time
health
monitoring
personalized
medicine.
Among
these,
electrochemical
are
particularly
advantageous,
due
excellent
signal
responsiveness,
cost-effectiveness,
miniaturization,
broad
applicability,
making
them
ideal
constructing
wearable
sweat
sensors.
In
this
study,
we
present
a
flexible
sensitive
platform
the
IFN-γ,
utilizing
DNA
hydrogel
with
favorable
loading
performance
sample
collection
capability,
application
mobile
software
achieves
immediate
data
analysis
processing.
This
integrates
three-dimensional
functionalized
IFN-γ-specific
aptamers
precise
target
recognition
efficient
collection.
Signal
amplification
is
achieved
through
target-triggered
catalytic
hairpin
assembly
(CHA),
hairpins
remarkably
enhancing
sensitivity.
Ferrocene-labeled
reporting
strands
immobilized
on
screen-printed
carbon
electrode
displayed
via
CHA-mediated
strand
displacement,
leading
measurable
reduction
electrical
signals.
These
changes
transmitted
custom-developed
portable
workstation
recording.
sensor
combines
specificity
aptamers,
advanced
amplification,
convenience
It
offers
high-sensitivity
approach
detecting
low-abundance
targets
paving
way
new
applications
point-of-care
diagnostics
monitoring.