SSRN Electronic Journal,
Год журнала:
2023,
Номер
unknown
Опубликована: Янв. 1, 2023
Rapid
prototyping
is
a
vital
manufacturing
method
for
fabricating
tissue
engineering
scaffolds.
Bone
scaffolds
possess
high
level
of
porosity
to
promote
cell
attachment,
spreading,
and
differentiation
considering
appropriate
biomechanical
properties.
Optimization
various
requirements
parameters
often
requires
extensive
experimental
work.
This
study
aims
design
simulate
3D-printed
PLA
ABS
with
two
lay-down
patterns
potentially
bone
also
distinguishing
the
mechanical
The
CAD-based
were
designed
simulated
finite
element
analysis
(FEA)
determine
3D
printing
technology
has
made
it
possible
produce
that
have
tailored
properties
like
strength,
nutrient
transport,
biological
growth.
comparison
between
indicates
scaffold
holds
higher
potential
being
used
in
regeneration.
Materials,
Год журнала:
2023,
Номер
16(24), С. 7518 - 7518
Опубликована: Дек. 5, 2023
The
internal
structure
of
the
scaffolds
is
a
key
factor
for
bone
regeneration.
In
this
study,
we
focused
on
space
dimensionality
within
scaffold
that
may
control
cell
migration
and
evaluated
effects
size
orientation
blood
vessels
amount
formation
in
scaffold.
carbonate
apatite
with
intrascaffold
allowing
one-dimensional
(1D),
two-dimensional
(2D),
or
three-dimensional
(3D)
were
fabricated
by
3D
printing.
These
had
same
size,
i.e.,
distances
between
struts
(~300
µm).
implanted
into
medial
condyle
rabbit
femurs
four
weeks.
Both
degree
formed
1D
2.5-
to
4.0-fold
greater
than
those
2D
migration.
Furthermore,
was
1.4-fold
larger
are
probably
because
limited
direction
prevented
branching
vessels,
whereas
spaces
provided
opportunity
random
vessel
branching.
Thus,
advantageous
inducing
large
oriented
resulting
formation.
Polymer-Plastics Technology and Materials,
Год журнала:
2024,
Номер
63(13), С. 1780 - 1793
Опубликована: Июнь 4, 2024
Reconstruction
in
cases
of
osteoporosis
or
accidents
often
requires
the
use
synthetic
bones
scaffolds,
with
hydroxyapatite
standing
out
as
a
preferred
material
due
to
its
biocompatibility.
This
study
focuses
on
production
and
characterization
hydroxyapatite-coated
3D-printed
bone
scaffolds.
The
structures
were
fabricated
by
blending
powder,
synthesized
through
solution
combustion
technique,
liquid
photopolymer,
followed
exposure
UV
irradiation.
resulting
hydroxyapatite/photopolymer
scaffolds
characterized
uniform
distribution
fine
powder
surface.
Subsequently,
these
underwent
coating
slurry,
experimenting
various
sintering
conditions.
Despite
decomposition
photopolymer
during
process,
coated
scaffold
displayed
an
increased
thickness
infill
line
within
pattern,
reduced
void
size
enhanced
compressive
strength.
Weibull
analysis
strength
indicated
high
likelihood
survival
at
4
MPa,
falling
acceptable
range
for
cancellous
comprehensive
showcased
potential
favorable
microstructure
mechanical
strength,
making
them
promising
applications
reconstruction.
SSRN Electronic Journal,
Год журнала:
2023,
Номер
unknown
Опубликована: Янв. 1, 2023
Rapid
prototyping
is
a
vital
manufacturing
method
for
fabricating
tissue
engineering
scaffolds.
Bone
scaffolds
possess
high
level
of
porosity
to
promote
cell
attachment,
spreading,
and
differentiation
considering
appropriate
biomechanical
properties.
Optimization
various
requirements
parameters
often
requires
extensive
experimental
work.
This
study
aims
design
simulate
3D-printed
PLA
ABS
with
two
lay-down
patterns
potentially
bone
also
distinguishing
the
mechanical
The
CAD-based
were
designed
simulated
finite
element
analysis
(FEA)
determine
3D
printing
technology
has
made
it
possible
produce
that
have
tailored
properties
like
strength,
nutrient
transport,
biological
growth.
comparison
between
indicates
scaffold
holds
higher
potential
being
used
in
regeneration.
