Liposomal Nano-Based Drug Delivery Systems for Breast Cancer Therapy: Recent Advances and Progresses
Anti-Cancer Agents in Medicinal Chemistry,
Год журнала:
2024,
Номер
24(12), С. 896 - 915
Опубликована: Март 26, 2024
Abstract:
Breast
cancer
is
a
highly
prevalent
disease
on
global
scale,
with
30%
incidence
rate
among
women
and
14%
mortality
rate.
Developing
countries
bear
disproportionate
share
of
the
burden,
while
greater
technological
advancements
exhibit
higher
incidence.
A
mere
7%
under
age
40
are
diagnosed
breast
cancer,
prevalence
this
ailment
significantly
diminished
those
aged
35
younger.
Chemotherapy,
radiation
therapy,
surgical
intervention
comprise
treatment
protocol.
However,
ongoing
quest
for
definitive
cure
continues.
The
propensity
stem
cells
to
metastasize
resistance
constitute
their
Achilles'
heel.
advancement
drug
delivery
techniques
that
target
specifically
holds
significant
promise
in
terms
facilitating
timely
detection
effective
intervention.
Novel
approaches
pharmaceutical
delivery,
including
nanostructures
liposomes,
may
bring
about
substantial
changes
way
managed.
These
systems
offer
multitude
advantages,
such
as
heightened
bioavailability,
enhanced
solubility,
targeted
tumor
destruction,
adverse
effects.
application
nano-drug
administer
anti-breast
medications
subject
research.
This
article
delves
into
domain
conventional
methods,
incorporation
nanotechnology
managerial
tactics,
strategic
aimed
at
tackling
its
core.
Язык: Английский
Graphene Oxide (GO)-Based Bioink with Enhanced 3D Printability and Mechanical Properties for Tissue Engineering Applications
Nanomaterials,
Год журнала:
2024,
Номер
14(9), С. 760 - 760
Опубликована: Апрель 26, 2024
Currently,
a
major
challenge
in
material
engineering
is
to
develop
cell-safe
biomaterial
with
significant
utility
processing
technology
such
as
3D
bioprinting.
The
main
goal
of
this
work
was
optimize
the
composition
new
graphene
oxide
(GO)-based
bioink
containing
additional
extracellular
matrix
(ECM)
unique
properties
that
may
find
application
bioprinting
biomimetic
scaffolds.
experimental
evaluated
functional
viscosity
and
complex
modulus,
printability,
mechanical
strength,
elasticity,
degradation
absorbability,
well
biological
cytotoxicity
cell
response
after
exposure
biomaterial.
findings
demonstrated
inclusion
GO
had
no
substantial
impact
on
rheological
but
it
did
enhance
properties.
This
enhancement
crucial
for
advancement
scaffolds
are
resilient
deformation
promote
their
utilization
tissue
investigations.
Furthermore,
GO-based
hydrogels
exhibited
much
greater
swelling,
absorbability
compared
non-GO-based
bioink.
Additionally,
these
biomaterials
showed
lower
cytotoxicity.
Due
its
properties,
recommended
use
models
vascular
system,
e.g.,
testing
drugs
or
hard
models.
Язык: Английский
Composites for BTE
Biological and medical physics series,
Год журнала:
2025,
Номер
unknown, С. 251 - 282
Опубликована: Янв. 1, 2025
Язык: Английский
Bone Extracellular Matrix
Biological and medical physics series,
Год журнала:
2025,
Номер
unknown, С. 79 - 105
Опубликована: Янв. 1, 2025
Nano-bioceramics
Biological and medical physics series,
Год журнала:
2025,
Номер
unknown, С. 217 - 249
Опубликована: Янв. 1, 2025
Development of poly (lactic acid) (PLA)-grafted maleic anhydride (MA) / poly(caprolactone) (PCL)/murexide composites for automotive potential panel applications
MRS Advances,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 25, 2025
Язык: Английский
Innovative Micro- and Nano-Architectures in Biomedical Engineering for Therapeutic and Diagnostic Applications
Micromachines,
Год журнала:
2025,
Номер
16(4), С. 419 - 419
Опубликована: Март 31, 2025
The
rapid
evolution
of
micro-
and
nano-architectures
is
revolutionizing
biomedical
engineering,
particularly
in
the
fields
therapeutic
diagnostic
micromechanics.
This
review
explores
recent
innovations
nanostructured
materials
their
transformative
impact
on
healthcare
applications,
ranging
from
drug
delivery
tissue
engineering
to
biosensing
diagnostics.
Key
advances
fabrication
techniques,
such
as
lithography,
3D
printing,
self-assembly,
have
enabled
unprecedented
control
over
material
properties
functionalities
at
microscopic
scales.
These
engineered
architectures
offer
enhanced
precision
targeting
controlled
release
delivery,
foster
cellular
interactions
improve
sensitivity
specificity
devices.
We
examine
critical
design
parameters,
including
biocompatibility,
mechanical
resilience,
scalability,
which
influence
clinical
efficacy
long-term
stability.
also
highlights
translational
potential
current
limitations
bringing
these
laboratory
research
practical
applications.
By
providing
a
comprehensive
overview
trends,
challenges,
future
perspectives,
this
article
aims
inform
inspire
further
development
that
hold
promise
for
advancing
personalized
medicine.
Язык: Английский
A Review Exploring the Wound-Healing Activity of Self-Healing Hydrogels: Fabrication, Characterization, Mechanism, and Biomedical Applications
Journal of Cluster Science,
Год журнала:
2024,
Номер
35(6), С. 2019 - 2037
Опубликована: Май 20, 2024
Abstract
The
natural
physiological
response
to
skin
injury
is
wound
healing.
However,
restore
continuity,
healing
a
complicated
process
that
involves
the
collaboration
of
variety
cell
types
and
other
mediators.
This
ultimately
results
in
tissue
regeneration
restoration
barrier
function.
Hydrogels
are
appealing
dosage
forms
for
biomedical
regenerative
medicine
since
they
composed
3D
networks
with
high
water
content
flexible
rheological
features.
can
self-heal
particularly
interesting
treatment
because
autonomously
their
original
functionalities
repair
structural
damage.
Recently,
use
self-healing
hydrogels
as
materials
has
attracted
increased
interest.
In
this
review,
systems
used
regeneration,
especially
healing,
will
be
explored.
A
focus
on
fabrication
methods,
characterization
tests,
mechanism
introduced,
along
applications
loaded
conventional
therapeutic
biomaterials.
addition,
differences
between
discussed.
Graphical
Язык: Английский
Advancements and Applications of 4D Bioprinting in Biomedical Science
Chinese Journal of Polymer Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 25, 2024
Язык: Английский
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges
Current Drug Targets,
Год журнала:
2024,
Номер
25(10), С. 649 - 669
Опубликована: Июнь 26, 2024
Breast
cancer
is
a
pervasive
global
health
issue
that
disproportionately
impacts
the
female
population.
Over
past
few
years,
there
has
been
considerable
interest
in
nanotechnology
due
to
its
potential
utility
creating
drug-delivery
systems
designed
combat
this
illness.
The
primary
aim
of
these
devices
enhance
delivery
targeted
medications,
optimise
specific
cells
receive
drugs,
tackle
treatment
resistance
malignant
cells,
and
introduce
novel
strategies
for
preventing
controlling
diseases.
This
research
aims
examine
methodologies
utilised
by
various
carrier
nanoparticles
context
therapeutic
interventions
breast
cancer.
main
objective
investigate
application
technologies
attain
timely
efficient
diagnosis
treatment.
Current
predominantly
examines
diverse
drug
chemotherapeutic
agents.
These
encompass
development
hydrogels,
micelles,
exosomes,
similar
compounds.
analyse
attributes,
intricacies,
notable
advancements,
practical
applications
system
clinical
settings.
Despite
demonstrated
efficacy
methodologies,
an
apparent
discrepancy
can
be
observed
between
progress
made
developing
innovative
approaches
their
widespread
implementation
It
critical
establish
robust
correlation
two
variables
effectiveness
medication
based
on
Язык: Английский