Social 'envirotyping' the ABCD study contextualizes dissociable brain organization and diverging outcomes DOI Creative Commons

Haily Merritt,

Mary Kate Koch,

Youngheun Jo

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Авг. 22, 2024

The environment, especially social features, plays a key role in shaping the development of brain, notably during adolescence. To better understand variation brain-environment coupling and its associated outcomes, we identified ''envirotypes,'' or different patterns environment experience, Adolescent Brain Cognitive Development Study by hierarchically clustering subjects. Two focal clusters, which accounted for 89.3% all participants, differed significantly on eight out nine youth-report quality measures, representing almost perfect complements. We then applied tools from network neuroscience to show envirotypes are with whole brain functional connectivity. Differences were distributed across but prominent Default Somatomotor Hand systems these clusters. Finally, examined how change over suite outcomes. resulting dynamic along dimensions stability quality, outcomes diverged based stability. Specifically, stable, high envirotype was most easily distinguished improving envirotype, while unstable worst Altogether, our findings represent significant contributions both developmental neuroscience, emphasizing variability dynamicity consequences.

Язык: Английский

The Impact of EU-Funded Educational Programs on the Socio-Economic Development of Romanian Students: A Multidimensional Analysis DOI Open Access
Monica Claudia Grigoroiu,

Cristina Țurcanu,

Cristinel Constantin

и другие.

Sustainability, Год журнала: 2025, Номер 17(5), С. 2057 - 2057

Опубликована: Фев. 27, 2025

One of the central goals 2030 Agenda for Sustainable Development is represented by inclusive and equitable education. This study investigates impact educational programs funded European Union on socio-economic situation Romanian students focusing eight key dimensions: poverty, social inequalities, juvenile crime, nutrition, discrimination, employability, quality life, health. The based a quantitative descriptive research design. data were collected from representative sample 1220 pre-university teachers. To identify differences between who benefited EU-funded project implementation did not have this opportunity, t-Student ANOVA tests used. cluster analysis (k-means) was applied to classify cases evolution indicators, binary logistic regression used factors influencing probability that belong groups with better performance in relation analyzed dimensions. Our findings revealed while education projects significantly contributed development students, series disparities still persist among coming low-income families. underline need more targeted policies. advanced statistical analyses importance early interventions through programs. Also, they integrated, strategies increase chances supporting equity reducing inequalities.

Язык: Английский

Процитировано

0

The role of socioeconomic status in shaping associations between sensory association cortex and prefrontal structure and implications for executive function DOI Creative Commons
Maya L. Rosen, Divyangana Rakesh, Rachel Romeo

и другие.

Developmental Cognitive Neuroscience, Год журнала: 2025, Номер unknown, С. 101550 - 101550

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Combined effects of prenatal ozone exposure and school/neighborhood environments on youth brain, cognition, and psychotic‐like experiences DOI Open Access

Tianjiao Kong,

Yongkang Yang, Feng Ji

и другие.

Journal of Child Psychology and Psychiatry, Год журнала: 2025, Номер unknown

Опубликована: Март 25, 2025

Humans are inevitably exposed to multiple physical and social environmental risk factors, potentially contributing psychiatric problems cognitive deficits; however, the combined effects of prenatal air pollution psychosocial environments on youth remain unclear. This longitudinal study aimed examine how ozone exposure interacts with at 9-10 years affect adolescent limbic system development, cognition, psychotic-like experiences (PLEs) 11-13 years. We analyzed data from 6,778 participants in Adolescent Brain Cognitive Development (ABCD) Study® two time points (baseline: 2-year follow-up). Prenatal was calculated as a 9-month average daily estimates based birth year address. Social factors included school environment neighborhood safety both points. Structural MRI measures bilateral amygdala hippocampus volumes Behavioral consisted cognition PLEs scores Moderation moderated mediation models cluster-robust standard errors were constructed effects, controlling for covariates. Children who prenatally greater had more unfavorable exhibited smaller increase left hippocampal volume, leading poorer PLEs. Moreover, children lived unsafe larger right volume. is first demonstrate pollutant adverse childhood highlighting an important neural mechanism underlying effects.

Язык: Английский

Процитировано

0

Brain development DOI
Divyangana Rakesh, Niousha Dehestani, Sarah Whittle

и другие.

Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 43 - 57

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

2

Neighborhood Socioeconomic Disadvantage and White Matter Microstructure of the Arcuate Fasciculus and Uncinate Fasciculus in Adolescents DOI Creative Commons

Artenisa Kulla,

Saché M. Coury,

Jordan M. Garcia

и другие.

Biological Psychiatry Global Open Science, Год журнала: 2023, Номер 4(1), С. 61 - 72

Опубликована: Окт. 14, 2023

Neighborhood or area-level socioeconomic disadvantage is associated with neural alterations across the lifespan. Few studies, however, have examined effects of neighborhood on white matter microstructure during adolescence, an important period development that coincides increased risk for psychopathology. In 200 adolescents (ages 13-20 years; 54.5% female, 4% non-binary) recruited from two studies enriched early adversity and depression, we whether derived census tract data was related to in several major tracts. We also depressive symptoms sex moderated these associations. Greater lower fractional anisotropy (FA) left arcuate fasciculus (β=-0.24, FDR-corrected p=0.035) right uncinate (β=-0.32, p=0.002), above beyond family-level status. Depressive significantly association between FA both (β=0.17, p=0.026) unemployment (β=0.22, p=0.004), such associations were only significant who reported less severe depression. Sex did not moderate disadvantage, particularly poverty education attainment levels, fasciculus, measures These patterns observed low levels suggesting must be cautious about generalizing findings youth struggle mental health difficulties.

Язык: Английский

Процитировано

5

Structural connectivity and its association with social connectedness in early adolescence DOI
Christina Driver, Lisa Jean Moore, Abdalla Z. Mohamed

и другие.

Behavioural Brain Research, Год журнала: 2022, Номер 440, С. 114259 - 114259

Опубликована: Дек. 14, 2022

Язык: Английский

Процитировано

8

More Than a Learning Environment: School Climate as a Protective Factor for Child Neurodevelopment and Mental Health? DOI
Sandra Thijssen

Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Год журнала: 2023, Номер 8(1), С. 6 - 8

Опубликована: Янв. 1, 2023

Язык: Английский

Процитировано

4

Pathways link environmental and genetic factors with structural brain networks and psychopathology in youth DOI
Anqi Qiu,

Chaoqiang Liu

Neuropsychopharmacology, Год журнала: 2023, Номер 48(7), С. 1042 - 1051

Опубликована: Март 17, 2023

Язык: Английский

Процитировано

4

Longitudinal sex-at-birth and age analyses of cortical structure in the ABCD Study® DOI Creative Commons
Andrew T. Marshall, Shana Adise, Eric Kan

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Июнь 11, 2024

Abstract While the brain continues to develop during adolescence, such development may depend on sex-at-birth. However, elucidation of differences be hindered by analytical decisions (e.g., covariate selection address body/brain-size differences) and typical reporting cross-sectional data. To further evaluate adolescent cortical development, we analyzed data from Adolescent Brain Cognitive Development Study SM , whose cohort 11,000+ youth participants with biannual neuroimaging collection can facilitate understanding neuroanatomical change a critical developmental window. Doubly considering individual in context group-level effects, regional changes thickness, sulcal depth, surface area, volume between two timepoints (∼2 years apart) 9-to 12-year-olds assigned male or female First, conducted linear mixed-effects models gauge how controlling for intracranial volume, whole-brain (WBV), summary metric mean thickness) influenced interpretations age-dependent change. Next, evaluated relative thickness area as function sex-at-birth age. Here, showed that WBV (thickness, volume) total were more optimal covariates; different covariates would have substantially altered our overall sex-at-birth-specific development. Further, provided evidence suggest aggregate is changing generally comparable across those sex-at-birth, corresponding happening at slightly older ages Overall, these results help elucidate trajectories early adolescence. Significance Statement most brain’s happens life, much it still Because many factors alter trajectories, important shape/timing (i.e., what constitutes development). affected choose analyze them. way researchers brain/body size affects interpret variation over time. consider similar patterns simply groups. These support relatively novel analyzing

Язык: Английский

Процитировано

1

The growing interdisciplinarity of developmental psychopathology: Implications for science and training DOI Creative Commons
Ian H. Gotlib, Jessica L. Buthmann, Jessica P. Uy

и другие.

Development and Psychopathology, Год журнала: 2024, Номер unknown, С. 1 - 11

Опубликована: Март 22, 2024

The field of developmental psychopathology has grown exponentially over the past decades, and become increasingly multifaceted. initial focus on understanding abnormal child psychology broadened to study origins psychopathology, with goals preventing alleviating disorder promoting healthy development. In this paper, we discuss how technological advances global events have expanded questions that researchers in can address. We do so by describing a longitudinal been conducting for dozen years. originally planned examine effects early adversity trajectories brain development, endocrine function, depressive symptoms across puberty; it since an interdisciplinary encompassing diverse domains like inflammation, sleep, biological aging, environment, functioning post-pandemic, believe will advance our neurobehavioral This increase breadth emerged from expansion field; encourage embrace these dynamic changes. context, challenges, opportunities, institutional changes related growing interdisciplinarity respect training next generation investigators mitigate burden mental illness youth.

Язык: Английский

Процитировано

1