The relationship between polysaccharide structure and its antioxidant activity needs to be systematically elucidated

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 270, С. 132391 - 132391

Опубликована: Май 17, 2024

Язык: Английский

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Fabrication of yeast β-glucan/sodium alginate/γ-polyglutamic acid composite particles for hemostasis and wound healing

Biomaterials Science, Год журнала: 2024, Номер 12(9), С. 2394 - 2407

Опубликована: Янв. 1, 2024

Particles with a porous structure can lead to quick hemostasis and provide good matrix for cell proliferation during wound healing.

Язык: Английский

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Mixture Containing 5% Polysaccharide Extract of Cerioporus squamosus (Huds.) Quélet, 5% Dexpanthenol, and 0.2% Hyaluronic Acid Shows In Vitro and In Vivo Wound Healing Properties

Pharmaceuticals, Год журнала: 2025, Номер 18(3), С. 416 - 416

Опубликована: Март 15, 2025

Background: This study explores wound healing and the antimicrobial potential of a natural formulation containing polysaccharide extract from Cerioporus squamosus, hyaluronic acid, dexpanthenol. Methods: Wound effects were assessed using HaCaT keratinocytes, while activity was evaluated against human skin pathogens microdilution assay. In vitro cytotoxicity tests ensured safety, whereas in vivo further investigated an animal model. Gene expression analysis performed to assess molecular mechanisms involved. Results: The unique glucan composition C. squamosus (15.38% α-glucans 7.91% β-glucans) deviated typical mushroom profiles, warranting exploration its bioactivity. polysaccharides promoted 25.35% closure after 24 hours, three-component achieved 35.81% closure. Antibacterial showed minimum inhibitory concentration (MIC) 0.44–1.75 mg/mL bactericidal (MBCs) 0.88–3.50 mg/mL, antifungal ranged 0.22 0.44 (MICs) 0.88 (minimum fungicidal concentration—MFC). data that 60% treated wounds fully closed by day 11, despite no statistically significant difference control. However, gene highlighted VEGF collagen upregulation, indicating enhancement on level. Conclusions: novel demonstrated consistent properties, supporting as safe effective treatment for chronic acute wounds.

Язык: Английский

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A dual-network hydrogel patch fabricated by alginate/sulfobetaine methacrylate enriched with Dictyophora indusiata β-glucans promotes diabetic wound repair

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142495 - 142495

Опубликована: Март 1, 2025

Язык: Английский

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Biochemical properties and application of a multi-domain β-1,3-1,4-glucanase from Fibrobacter sp.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 273, С. 133026 - 133026

Опубликована: Июнь 7, 2024

Язык: Английский

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Unlocking the potential of beta-glucans: a comprehensive review from synthesis to drug delivery carrier potency

Drug Delivery and Translational Research, Год журнала: 2024, Номер 15(2), С. 483 - 507

Опубликована: Авг. 9, 2024

Язык: Английский

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Self-assembled near-infrared-photothermal antibacterial Hericium erinaceus β-glucan/tannic acid/Fe (III) hydrogel for accelerating infected wound healing

Carbohydrate Polymers, Год журнала: 2024, Номер 348, С. 122898 - 122898

Опубликована: Окт. 23, 2024

Язык: Английский

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One-step construction of silver nanoparticles immersed hydrogels by triple-helix β-glucans and the application in infectious wound healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 137146 - 137146

Опубликована: Окт. 1, 2024

Язык: Английский

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Dynamic bond crosslinked maca polysaccharide hydrogels with reactive oxygen species scavenging and antibacterial effects on infected wound healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 276, С. 133471 - 133471

Опубликована: Июнь 26, 2024

Язык: Английский

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Hericium erinaceus β-glucan/tannic acid hydrogels based on physical cross-linking and hydrogen bonding strategies for accelerating wound healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 279, С. 135381 - 135381

Опубликована: Сен. 6, 2024

Язык: Английский

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