Trends in sustainable chitosan-based hydrogel technology for circular biomedical engineering: A review

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 276, С. 133823 - 133823

Опубликована: Июль 11, 2024

Язык: Английский

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Injectable self-healing alginate/PEG hydrogels cross-linked via thiol-Michael addition bonds for hemostasis and wound healing

Carbohydrate Polymers, Год журнала: 2024, Номер 348, С. 122864 - 122864

Опубликована: Окт. 16, 2024

Язык: Английский

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Rapid Fluid-Induced-Expanding Chitosan-Derived Hemostatic Sponges with Excellent Antimicrobial and Antioxidant Properties for Incompressible Hemorrhage and Wound Healing

Biomacromolecules, Год журнала: 2025, Номер 26(1), С. 689 - 704

Опубликована: Янв. 1, 2025

Chitosan-based materials are known for their excellent biocompatibility and inherent hemostatic properties. However, efficiency is significantly affected by poor wettability mechanical strength. Herein, we developed a novel super elastic sponge from mussel-inspired chitosan modified with long alkyl catechol functional groups (HMCC) via simple freezing-drying procedure. The incorporation of decanal in the HMCC enhances its antimicrobial antioxidant properties facilitates multiple interactions blood cells, thus promoting enrichment rapid hemostasis. Moreover, sponges exhibit high compressibility fluid-induced size recovery capacity, enabling wound shape adaptation to ensure minimizing irritation. In vivo experiments revealed that possessed enhanced procoagulant, hemostasis abilities, favorable degradability could promote healing rat skin model. These results highlight potential as promising solution clinical management major bleeding.

Язык: Английский

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A layer-cake structure composite of carboxymethyl chitosan crosslinked intercalation of bentonite for antimicrobial and repair effects

Materials Today Communications, Год журнала: 2025, Номер unknown, С. 111652 - 111652

Опубликована: Янв. 1, 2025

Язык: Английский

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Carboxymethyl chitosan-gelatin based films filled with whey protein-stabilized nanoscale essential oils for skin wound healing: In vivo and in vitro studies

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141119 - 141119

Опубликована: Фев. 1, 2025

Язык: Английский

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Multifunctional coaxial gelatin/polylactic acid three-dimensional nanofibrous scaffolds for diabetic wounds

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141525 - 141525

Опубликована: Фев. 1, 2025

Язык: Английский

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Natural polysaccharides combined with mussel-inspired adhesion for multifunctional hydrogels in wound hemostasis and healing: A review

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136965 - 136965

Опубликована: Окт. 30, 2024

Язык: Английский

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Self-Healing Oxidized Dextran/Sodium Alginate Hydrogel Dressing with Hemostatic Activity Speeds Up Wound Healing in Burn Injuries

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер 17(2), С. 2940 - 2951

Опубликована: Янв. 7, 2025

This study introduced a hydrogel dressing, termed SODex-gel, which was constructed by establishing Schiff base and hydrogen bonds with the precursors of oxidized dextran (ODex) succinic dihydrazide (SD)-modified sodium alginate (SD-mod-SA). Through comprehensive in vitro vivo studies, adhesive properties, self-healing capabilities, hemostatic potential, wound healing efficacy SODex-gel dressing were meticulously evaluated. The 1H NMR, FTIR, TGA analyses confirmed fabrication its constituent elements. Scanning electron microscopy (SEM) imaging showcased uniform pore structures dressing. In assessments demonstrated that noncytotoxic exhibits strong adhesion, enabling it to attach various surfaces. Noteworthy findings from studies mouse liver incisions tail amputation models proved ability Moreover, their remarkable wound-healing capabilities prominently through treatment model afflicted burn skin injuries. Evidence neovascularization effects corroborated upregulation CD31 vascular endothelial growth factor (VEGF) expression treated samples. Collectively, experimental data unequivocally established is promising therapeutic approach accelerate recovery, thereby exhibiting substantial potential for clinical applications treating

Язык: Английский

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Exosome-Loaded Tannic Acid–Thioctic Acid Hydrogel Enhances Wound Healing in Coagulation Disorders

Materials Today Bio, Год журнала: 2025, Номер 31, С. 101496 - 101496

Опубликована: Янв. 25, 2025

Язык: Английский

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Fabrication of amino-capped Pluronic F127 with aldehyde dextran chains: A strategy improving extensibility, compressibility and self-healing hydrogel for wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 304, С. 140774 - 140774

Опубликована: Фев. 10, 2025

Язык: Английский

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