The
purpose
of
nanotechnology-based
drug
delivery
systems
or
novel
is
to
improve
the
effectiveness
therapy,
and
their
promising
properties
have
led
increasing
significance
in
management
cancer.
researchers
primarily
focused
on
designing
nanocarriers,
like
nanoparticles
(NPs),
that
can
effectively
deliver
drugs
target
cells
respond
specifically
conditions
particular
Whether
passive
active
targeting,
these
nanocarriers
therapeutic
cargoes
tumor
site
release
from
systems.
this
study
provide
recent
scientific
literature
key
findings
as
well
community
medical
pharmaceutical
domains
by
reporting
current
advancements
development
NPs
for
treatment
different
malignant
solid
tumors,
such
colorectal,
pancreatic,
prostate,
cervical
Frontiers in Immunology,
Год журнала:
2025,
Номер
16
Опубликована: Март 24, 2025
Curcumin
has
a
clear
immunopharmacological
effect
and
plays
an
important
role
as
immune
agent
in
various
diseases
tumor
immunotherapy.
To
comprehensively
scientifically
clarify
reflect
the
development
process,
current
status,
research
trends
of
curcumin
field
regulation,
to
provide
reliable
insights
for
discipline
strategies
future
expansion,
this
study
systematically
analyzes
3939
valid
articles
related
immunity
published
between
2004
2024
from
Web
Science
database.
Using
Citespace
R-bibliometrix
software
bibliometric
analysis,
we
create
visual
knowledge
maps
multiple
dimensions
including
overall
publication
output,
influential
entities,
highly
cited
papers,
topics
hotspots.
The
results
indicate
that
number
publications
citations
is
currently
rapid
phase.
China
occupies
core
position
but
low
collaboration
intensity.
Egyptian
Knowledge
Bank
(EKB)
institution
with
highest
volume.
Moreover,
cluster
analysis
reveals
hotspots
are
gradually
shifting
fundamental
pathology
involving
broad
social
environmental
influences.
top
five
keywords
most
explosive
citations—curcumin,
inflammation,
apoptosis,
oxidative
stress,
cancer—represent
focused
topics.
Currently,
immunology
developed
diversified
perspective,
accumulating
significant
areas
active
substance
basis,
pharmacological
activity,
anti-inflammatory,
anti-cancer
studies.
thematic
evolution
curcumin’s
immunological
mechanisms
summarized
article
guidance
directions.
