A review of chitosan-based multifunctional nanocomposites for drug/gene/protein delivery and gene therapy in cancer treatments: Promises, challenges and outlooks
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 141394 - 141394
Опубликована: Фев. 1, 2025
Язык: Английский
Colorimetric Chitosan Films with Tunable Drug Release Ratio: Effect of Citric Acid and Acetic Acid Concentration Ratio and Drying Temperature
ACS Omega,
Год журнала:
2025,
Номер
10(9), С. 9088 - 9095
Опубликована: Фев. 26, 2025
This
study
successfully
controlled
the
mechanical
structure
of
chitosan
films
by
regulating
interactions
between
molecules
through
variations
in
concentration
ratio
citric
and
acetic
acids
within
films.
Additionally,
precise
drug
release
was
achieved
adjusting
drying
temperature
during
synthesis.
The
key
issue
addressed
is
challenge
achieving
control
biodegradable
materials.
Inaccurate
can
lead
to
ineffective
treatment
or
adverse
side
effects,
limiting
therapeutic
efficacy
increasing
healthcare
challenges.
main
objective
fine-tune
films'
composition
properties
achieve
predictable
over
ratios.
Our
results
show
that
acid
enhanced
ratio,
while
higher
temperatures
reduced
likely
due
structural
changes
film.
Furthermore,
caused
varying
enabled
successful
tensile
strength
strain
we
developed
capable
visually
indicating
color
before
after
release,
providing
a
simple
effective
method
for
real-time
monitoring.
Despite
these
promising
results,
challenges
remain,
such
as
improving
biocompatibility
use
complex
biological
environments.
Future
research
will
focus
on
enhancing
durability,
conducting
further
tests
systems,
exploring
methods
increase
their
long-term
performance.
Язык: Английский
4D Bioprinting for Personalized Medicine, Innovations in Implant Fabrication and Regenerative Therapies
Senthil Maharaj Kennedy,
Manigandan Sekar,
A. Vasanthanathan
и другие.
Polymer-Plastics Technology and Materials,
Год журнала:
2025,
Номер
unknown, С. 1 - 26
Опубликована: Март 30, 2025
Язык: Английский
3D Printing in Wound Healing: Innovations, Applications, and Future Directions
Cureus,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 8, 2024
The
field
of
wound
healing
faces
significant
challenges,
particularly
in
the
treatment
chronic
wounds,
which
often
result
prolonged
times
and
complications.
Recent
advancements
3D
printing
technology
have
provided
innovative
solutions
to
these
offering
tailored
precise
approaches
care.
This
review
highlights
role
enhancing
healing,
focusing
on
its
application
creating
biocompatible
scaffolds,
custom
dressings,
drug
delivery
systems.
By
mimicking
extracellular
matrix
(ECM)
facilitating
cell
proliferation,
3D-printed
biomaterials
potential
significantly
accelerate
process.
In
addition,
bioprinting
enables
production
functional
skin
substitutes
that
can
be
customized
for
individual
patients.
Despite
promise
technologies,
several
challenges
remain,
including
need
improved
vascularization,
cost
concerns,
regulatory
hurdles.
future
lies
continued
integration
with
emerging
technologies
such
as
4D
bioelectronics,
providing
opportunities
personalized
on-demand
therapies.
explores
current
state
care,
technologies.
Язык: Английский
Estructuras tipo origami en el desarrollo de biomateriales inteligentes a partir de impresión 4D
PÄDI Boletín Científico de Ciencias Básicas e Ingenierías del ICBI,
Год журнала:
2024,
Номер
12, С. 224 - 232
Опубликована: Дек. 13, 2024
La
manufactura
aditiva
tiene
un
gran
potencial
en
el
campo
de
los
biomateriales
por
su
capacidad
para
desarrollar
diseños
intrincados
y
complejos.
Este
estudio
presenta
una
revisión
sobre
papel
la
creación
estructuras
tipo
origami
inteligentes
a
partir
biopolímeros
con
respuesta
ante
estímulos
externos
(impresión
4D).
Desde
década
1990,
ingeniería
tejidos
ha
dependido
medida
andamios,
siendo
punto
clave
promover
adhesión
celular,
proliferación
diferenciación,
integrando
biología
celular
ciencia
materiales.
impresión
4D
constituye
solución
las
limitaciones
andamios
convencionales.
Esta
tecnología
innovadora
permite
integración
origami,
cambio
forma
como
estímulos,
lo
cual
incrementa
crear
dinámicos,
plegables
receptivos,
abriendo
nuevas
vías
medicina
regenerativa.