Inflammatory
bowel
disease
(IBD)
is
a
gastrointestinal
immune
that
requires
clear
diagnosis,
timely
treatment,
and
lifelong
monitoring.
The
diagnosis
monitoring
methods
of
IBD
mainly
include
endoscopy,
imaging
examination,
laboratory
which
are
constantly
developed
to
achieve
early
definite
accurate
In
recent
years,
with
the
development
nanotechnology,
have
been
remarkably
enriched.
Nanomaterials,
characterized
by
their
minuscule
dimensions
can
be
tailored,
along
distinctive
optical,
magnetic,
biodistribution
properties,
emerged
as
valuable
contrast
agents
for
targeted
endoscopy.
Through
both
active
passive
targeting
mechanisms,
nanoparticles
accumulate
at
site
inflammation,
thereby
enhancing
detection.
This
review
comprehensively
outlines
existing
detection
techniques,
expounds
upon
utilization
in
offers
insights
into
future
potential
vitro
diagnostics.
Abstract
1,8‐Naphthalimide
fluorophore,
as
the
classical
skeleton
for
fluorescent
functional
molecules,
has
gained
much
attention
in
chemistry
and
biomedical
field
due
to
its
excellent
properties,
photostability,
structural
flexibility.
The
rational
design
of
substituents
on
C‐4
position
N
‐position
1,8‐naphthalimide
chromophore
can
provide
specific
functions
such
fluorescence
sensing,
energy‐trapping,
targeting.
This
review
presents
progress
1,8‐naphthalimide‐based
sensors
metal
ions
biological
1,8‐naphthalimide‐functionalized
photosensitive
dyes
over
past
years.
We
summarize
general
molecular
strategies,
recent
developments
innovative
photosensitizers,
challenges,
wishing
promote
new
ideas
developing
smart
molecules
from
derivatives.
Critical Reviews in Analytical Chemistry,
Год журнала:
2025,
Номер
unknown, С. 1 - 21
Опубликована: Фев. 19, 2025
Manganese
is
an
essential
metal
ion
involved
in
various
biological
and
environmental
processes,
but
its
excess
can
lead
to
toxicity,
particularly
affecting
the
nervous
system.
Therefore,
developing
selective
sensitive
detection
methods
for
Mn2+
ions
of
paramount
importance.
Colorimetric
fluorimetric
chemosensors
have
emerged
as
promising
tools
due
their
simplicity,
cost-effectiveness,
real-time
monitoring
capabilities.
This
review
discusses
recent
advances
colorimetric
that
exhibit
distinct
color
or
fluorescence
changes
upon
interaction
with
ions.
The
explores
different
organic
nanomaterials,
focusing
on
mechanisms
sensing,
sensitivity,
selectivity,
practical
applications
monitoring,
healthcare,
food
safety.
article
also
provides
insights
into
future
research
directions
aimed
at
overcoming
these
challenges,
improving
chemosensor
performance,
expanding
applicability
diverse
real-world
scenarios.
