Omics approaches in understanding the benefits of plant-microbe interactions
Frontiers in Microbiology,
Год журнала:
2024,
Номер
15
Опубликована: Май 27, 2024
Plant-microbe
interactions
are
pivotal
for
ecosystem
dynamics
and
sustainable
agriculture,
influenced
by
various
factors,
such
as
host
characteristics,
environmental
conditions,
human
activities.
Omics
technologies,
including
genomics,
transcriptomics,
proteomics,
metabolomics,
have
revolutionized
our
understanding
of
these
interactions.
Genomics
elucidates
key
genes,
transcriptomics
reveals
gene
expression
dynamics,
proteomics
identifies
essential
proteins,
metabolomics
profiles
small
molecules,
thereby
offering
a
holistic
perspective.
This
review
synthesizes
diverse
microbial-plant
interactions,
showcasing
the
application
omics
in
mechanisms,
nitrogen
fixation,
systemic
resistance
induction,
mycorrhizal
association,
pathogen-host
Despite
challenges
data
integration
ethical
considerations,
approaches
promise
advancements
precision
intervention
resilient
agricultural
practices.
Future
research
should
address
challenges,
enhance
technology
resolution,
explore
epigenomics,
understand
plant-microbe
under
conditions.
In
conclusion,
technologies
hold
immense
optimizing
strategies
fortifying
alliances,
paving
way
agriculture
stewardship.
Язык: Английский
Rhizosphere Metabolite Dynamics in Continuous Cropping of Vineyards: Impact on Microflora Diversity and Co-occurrence Networks
Microbiological Research,
Год журнала:
2025,
Номер
296, С. 128134 - 128134
Опубликована: Март 7, 2025
Язык: Английский
Prioritizing Citrullus colocynthis accessions and fruit parts with promising antibacterial activity and adaption to the hot climate of the UAE for the future pharmaceutical industry
F1000Research,
Год журнала:
2025,
Номер
14, С. 277 - 277
Опубликована: Март 10, 2025
Background
The
rise
of
multidrug-resistant
pathogens
and
emerging
new
microbes
due
to
climate
change
highlight
the
urgent
need
for
alternative
antimicrobials.
Plants,
as
they
adapt
environmental
shifts,
produce
diverse
metabolites
with
potent
antibacterial
properties,
offering
a
sustainable
source
combat
antibiotic
resistance
microbial
threats.
In
this
context,
Citrullus
colocynthis
fruits,
known
their
antimicrobial
activity
adaptation
hot
Gulf
region,
were
screened
identify
accessions
strong
distinct
metabolic
profiles.
Methods
rinds
pulps
three
C.
effectiveness
against
Staphylococcus
aureus
Escherichia
coli.
Minimum
inhibitory
concentration
(MIC50)
tests
determined
levels,
GC-MS/MS
profiling
analyzed
chemical
composition
rind
pulp
extracts.
Enrichment
network
analyses
performed
pathways
potential
bacterial
targets.
Results
Rind
extracts
demonstrated
stronger
than
pulp,
accession
S2
showing
highest
S.
(MIC50
=
15.74
μg/ml),
outperforming
other
accessions.
Metabolic
revealed
metabolite
clusters
between
containing
unique
compounds
like
butyric
acid,
α-linolenic
β-sitosterol.
analysis
indicated
that
unsaturated
fatty
acid
biosynthesis
metabolism
enriched
in
rind,
supporting
its
potency.
Network
pinpointed
synthase
enzymes
(FabZ,
FabI,
FabH)
targets
acids.
Conclusions
profiles
especially
S2,
underscore
plant-based
nutraceuticals.
Its
adaptability
properties
present
promising
strategy
combating
pathogens.
Язык: Английский
Novel Strategies for Designing Climate‐Smart Crops to Ensure Sustainable Agriculture and Future Food Security
Journal of Sustainable Agriculture and Environment,
Год журнала:
2025,
Номер
4(2)
Опубликована: Март 31, 2025
ABSTRACT
To
fulfil
food
and
nutritional
demand
for
nine
billion
people
by
the
mid‐21st
century,
global
production
must
increase
60%
regardless
of
challenges
such
as
environmental
pollution,
water
scarcity
land
degradation.
Climate
change
exacerbates
frequency
intensity
biotic
abiotic
stresses,
which,
in
turn,
severely
compromise
crop
yields,
jeopardize
supply,
deteriorate
sustainable
development
goals
achieving
safety,
limit
climate‐smart
production.
Current
consumption
practices
negatively
influence
environment,
posing
a
major
threat
to
ecosystem
human
health.
Addressing
these
critical
issues
achieve
agriculture
necessitates
designing
future
crops
employing
cutting‐edge
breeding
strategies
enhanced
productivity
with
minimal
footprints.
This
endeavour
requires
comprehensive
understanding
plant
stress
adaptation,
signalling
pathways
mitigation
mechanisms.
In
this
review,
we
first
explain
diverse
impacts
ongoing
climate
events
on
Subsequently,
outline
various
tackle
change,
including
agronomic
practices,
advanced
technologies
physiological
molecular
mechanisms
tolerance.
We
also
discuss
engineering
superior
tolerance
disease
resistance
nurturing
healthy
microbial
partnerships
between
plants
soil
ensure
nutrition
security
current
populations
amidst
mounting
challenges.
Язык: Английский
The rhizobacterial Priestia megaterium strain SH-19 mitigates the hazardous effects of heat stress via an endogenous secondary metabolite elucidation network and molecular regulation signalling
BMC Plant Biology,
Год журнала:
2024,
Номер
24(1)
Опубликована: Сен. 4, 2024
Язык: Английский
Beyond Correlation: Understanding the Causal Link Between Microbiome and Plant Health
Heliyon,
Год журнала:
2024,
Номер
10(23), С. e40517 - e40517
Опубликована: Ноя. 19, 2024
Язык: Английский
Integrated Metabolomics and Transcriptomic Analysis of Cellular Stress Responses: Elucidating Metabolic Pathways and Regulatory Networks
Indus journal of bioscience research.,
Год журнала:
2024,
Номер
2(2), С. 1191 - 1197
Опубликована: Дек. 22, 2024
Cellular
stress
responses
are
vital
for
maintaining
homeostasis
and
enabling
adaptation
to
environmental
physiological
challenges.
This
study
employed
an
integrated
metabolomic
transcriptomic
approach
investigate
the
regulatory
networks
metabolic
pathways
underlying
these
responses.
Conducted
between
July
2023
December
2024
in
Karachi,
Pakistan,
research
utilized
cutting-edge
technologies,
including
real-time
PCR,
high-performance
liquid
chromatography
(HPLC),
gas
chromatography-mass
spectrometry
(GC-MS),
next-generation
sequencing
(NGS).
Biological
samples
representing
various
conditions,
such
as
oxidative
stress,
nutrient
deprivation,
stressors,
were
collected
analyzed
under
strict
ethical
protocols.
RNA
(RNA-Seq)
revealed
1,250
differentially
expressed
genes
(DEGs),
with
notable
upregulation
of
GPX1
SOD2,
indicating
enhanced
detoxification
stress.
Concurrently,
profiling
identified
significant
alterations
metabolites,
elevated
glutathione,
lactate,
proline,
highlighting
adaptive
shifts
glycolysis,
reactive
oxygen
species
(ROS)
detoxification,
osmoprotection.
Integrative
analysis
using
Weighted
Gene
Co-expression
Network
Analysis
(WGCNA)
pinpointed
key
hubs,
HIF1A
succinate,
central
nodes
stress-specific
networks.
comprehensive
multi-omics
provided
actionable
insights
into
molecular
mechanisms
cellular
The
findings
hold
translational
potential
agriculture
medicine,
particularly
enhancing
crop
resilience
developing
targeted
therapies
stress-related
disorders.
Despite
limitations
vitro
models,
this
underscores
value
multi-layered
omics
analyses
elucidating
lays
groundwork
future
integrative
Язык: Английский