Synergistic Toxic Effects and Mechanistic Insights of Beta-cypermethrin and Pyraclostrobin Exposure on Hook Snout Carp (Opsariichthys bidens): A Biochemical, Transcriptional, and Molecular Approach

Environmental Pollution, Год журнала: 2024, Номер 358, С. 124535 - 124535

Опубликована: Июль 11, 2024

Язык: Английский

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Aclonifen induces bovine mammary gland epithelial cell death by disrupting calcium homeostasis and inducing ROS production

Pesticide Biochemistry and Physiology, Год журнала: 2021, Номер 181, С. 105011 - 105011

Опубликована: Дек. 14, 2021

Язык: Английский

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Niclosamide subacute exposure alters the immune response and microbiota of the gill and gut in black carp larvae, Mylopharyngodon piceus

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 279, С. 116512 - 116512

Опубликована: Май 27, 2024

Niclosamide (NIC) is a commonly used insecticide and molluscicide in the prevention treatment of parasitic diseases fish. The utilization NIC has potential to disrupt microbial community present on mucosal tissue fish, leading localized inflammatory responses. objective this study was evaluate impact immune system bacterial populations within gill gut Mylopharyngodon piceus. Fish were subjected varying concentrations NIC, including control group (0 μg/L), low (15% 96 h LC50, LNG, 9.8 high (80% HNG, 52.5 μg/L). Gill samples collected 28 days post-exposure for analysis. findings revealed that 96-h LC50 determined be 65.7 μg/L, histopathological examination demonstrated exposure resulted filament subepithelial edema, exfoliation, degeneration, decrease length. Furthermore, exhibited apical enterocyte degeneration leucocyte infiltration following exposure. Additionally, led significant elevation levels immunoglobulin M (IgM), complement component 3 (C3), 4 (C4) both tissues. Moreover, activity lysozyme (LYZ) enhanced gill, while activities peroxidase (POD) T (IgT) increased tissue. mRNA expression c3, c9, tnfα, il6, il8, il11 tissue, decreasing c3 il8 natural resistance-associated macrophage protein (nramp) increased, liver-expressed antimicrobial peptide 2 (leap2) decreased And hepcidin (hepc) rose but fell also richness diversity, which significantly differed from group, although separation not In conclusion, administration alterations response microbiota it noted gills displayed heightened vulnerability sublethal effects comparison

Язык: Английский

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Entomopathogenic fungi against the dengue vector Aedes aegypti: laboratory and semifield assessment

Contribuciones a las Ciencias Sociales, Год журнала: 2024, Номер 17(6), С. e7559 - e7559

Опубликована: Июнь 18, 2024

Aedes aegypti, in addition to its association with arboviruses of significant public health concern, poses a considerable challenge the scientific community, which is actively working devise innovative strategies address this threat. Entomopathogenic fungi (EPF) are important bioagents for insect pest control. This study aimed evaluate virulence EPF against Ae. aegypti larvae and adults under laboratory semifield conditions. Conidia powder from M. anisopliae CG 153 or B. bassiana 479, at concentrations ranging 1×105 1×108 conidia/mL, was tested (N=30) conditions, while conidia suspension used via impregnated filter paper method. Survival curves were compared using Log-rank test. Both isolates exhibited adults, survival rates 0% 64% 20% 76%, respectively. Subsequently, both fungi, concentration 107 (N=60) Under showed 12% 35% 5% 20%, The tests produced promising results decreasing mosquito rates. Consequently, concludes that CG153 479 have potential serve as eco-friendly insecticides mosquitoes, thus warranting further exploration bioprospecting EPF-based products.

Язык: Английский

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In Vitro Assessment of Metarhizium Anisopliae Pathogenicity Against Aedes Aegypti Life Stages

Neotropical Entomology, Год журнала: 2024, Номер 53(6), С. 1260 - 1270

Опубликована: Окт. 9, 2024

Язык: Английский

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