Toxicology Research,
Год журнала:
2024,
Номер
14(1)
Опубликована: Дек. 23, 2024
Abstract
Aclonifen
is
a
diphenyl
ether
herbicide
being
included
in
the
list
of
priority
substances.
Nevertheless,
data
related
to
its
sublethal
effects
on
fish
are
limited.
Therefore,
present
study
has
been
carried
out
investigate
toxic
aclonifen
juvenile
Oncorhynchus
mykiss
following
24,
48,
72
and
96
hours
application
concentrations
12.7,
63.5
127
μg/L.
The
resulted
altered
blood
biochemistry
appearing
as
hyperglycemia,
decreased
cholesterol
induced
activities
transaminases
ALT
AST.
inhibition
AChE
brain,
gill
liver
was
unimportant
revealing
weak
potential
anticholinesterase.
induction
recorded
for
SOD,
CAT,
GPx
GST
accompanied
with
sustained
elevation
TBARS
PC
levels.
It
demonstrates
both
pro-oxidant
oxidation
lipid
proteins
resulting
loss
membrane
integrity
protein
function.
Hyperglycemic
condition
levels
might
be
proposed
general
adaptive
responses
compensate
increased
energy
demand.
integrative
assessment
multi-biomarker
shows
concentration
duration
rise
calculated
indexes.
SOD
achieved
maximum
scores
liver,
respectively.
Considering
results,
oxidative
stress
inducing
anticholinesterase
activity
along
disturbing
impact
were
evidenced.
Moreover,
adverse
affects
observed
after
short
term
O.
mykiss,
risk
may
cause
at
population
level
aquatic
ecosystems
emphasizing
importance
pesticide
regulations
avoid
impacts
non-target
species.
Fish Physiology and Biochemistry,
Год журнала:
2025,
Номер
51(2)
Опубликована: Март 25, 2025
Overusing
the
insecticide
imidacloprid
(IMD)
in
agriculture
has
led
to
its
presence
water
bodies,
causing
serious
environmental
issues
and
fish
toxicity.
This
study
explored
potential
benefits
of
grape
seed
extract
(GSE)
mitigating
IMD-induced
growth
hormonal
gastrointestinal
toxicity
Nile
tilapia.
A
total
240
healthy
juvenile
tilapias
Oreochromis
niloticus
(O.
niloticus),
weighing
an
average
11.44
±
2.01
g
at
2
weeks
age,
were
divided
equally
into
four
groups,
each
with
three
replicates.
The
control
group
received
no
special
treatment,
while
second
was
given
a
diet
containing
2%
GSE®.
third
exposed
1.5
µg
IMD
per
liter
water.
fourth
subjected
same
exposure
fed
These
treatments
administered
continuously
for
75
days.
Growth
indices,
survival
rate,
biochemical
parameters,
digestive
enzymes
measured.
In
addition,
growth-related
hormones,
intestinal
malondialdehyde
(MDA),
catalase
(CAT)
evaluated.
Histological
evaluations
conducted
on
stomach,
duodenum,
ileum,
hepatopancreas,
alongside
body
composition
analysis.
Exposure
delayed
growth,
impaired
serum
biochemistry
enzyme
activity,
altered
composition,
obstructed
responses,
decreased
CAT
increased
MDA.
All
tissues
exhibited
signs
degradation.
Combining
dietary
GSE®
improved
former
parameters
affected
by
IMD.
conclusion,
research
suggests
that
incorporating
may
help
reduce
adverse
effects
tilapia,
presenting
promising
opportunity
address
impacts
contamination
aquatic
ecosystems.
Aquaculture Nutrition,
Год журнала:
2025,
Номер
2025(1)
Опубликована: Янв. 1, 2025
Achillea
wilhelmsii
(AW),
a
plant
rich
in
flavonoids,
including
lutein,
apigenin,
rutin,
and
phenolic
compounds
with
antioxidant,
antibacterial,
antifungal
properties,
is
used
traditional
medicine.
In
this
study,
the
impact
of
AW
extract
on
growth,
immune
response,
biochemical
indices
rainbow
trout
(Oncorhynchus
mykiss)
was
investigated.
Over
8
weeks,
fish
were
fed
diets
supplemented
varying
concentrations
(0%,
0.5%,
1%,
or
2%).
No
significant
differences
observed
growth
performance,
glucose
levels,
key
enzymes
such
as
lactic
acid
dehydrogenase,
alanine
transaminase,
aspartate
aminotransferase
(AST)
between
AW-supplemented
groups
control
group.
However,
that
received
supplementation
showed
significantly
higher
levels
total
serum
protein,
lysozyme
activity,
superoxide
dismutase
(SOD)
immunoglobulin
M
(IgM).
Moreover,
AW-fed
exhibited
lower
mortality
after
exposure
to
Yersinia
ruckeri.
conclusion,
could
enhance
function
decrease
Y.
Therefore,
using
(1%
2%)
aquaculture
be
justified
means
increase
resistance
pathogens
improve
system
performance
fish.
