Chemistry - An Asian Journal,
Год журнала:
2021,
Номер
16(20), С. 3068 - 3081
Опубликована: Авг. 23, 2021
Abstract
2‐Pyrrolidones
have
aroused
enormous
interest
as
a
useful
structural
moiety
in
drug
discovery;
however,
not
only
does
their
syntheses
suffer
from
low
selectivity
and
yield,
but
also
it
requires
high
catalyst
loadings.
The
radical
cyclization
of
1,
n
‐enynes
‐dienes
has
demonstrated
to
be
an
attractive
method
for
the
synthesis
2‐pyrrolidones
due
its
mild
reaction
conditions,
fewer
steps,
higher
atom
economy,
excellent
functional
group
compatibility,
regioselectivity.
Furthermore,
receptors
with
unsaturated
bonds
(i.
e.
‐dienes)
play
crucial
role
realizing
because
ability
selectively
introduce
one
or
more
sources.
In
this
review,
we
discuss
representative
examples
methods
involving
published
last
five
years
each
prominent
design
mechanism,
providing
favorable
tools
valuable
2‐pyrrolidone
variety
applications.
Green Chemistry,
Год журнала:
2021,
Номер
23(11), С. 3950 - 3954
Опубликована: Янв. 1, 2021
An
electrochemical
multicomponent
reaction
was
established
under
catalyst-,
chemical-oxidant-free
and
mild
conditions,
which
provides
an
eco-friendly
simple
protocol
for
constructing
4-selanylpyrazoles
from
easily
available
raw
materials
with
high
yields.
Organic Chemistry Frontiers,
Год журнала:
2021,
Номер
8(18), С. 5206 - 5228
Опубликована: Янв. 1, 2021
Various
alkene
difunctionalization
reactions
involving
nitridization,
diamination,
azidation,
oxyamination,
carboamination,
aminohalogenation,
and
nitration
are
introduced
in
this
review.
Green Chemistry,
Год журнала:
2023,
Номер
25(14), С. 5539 - 5542
Опубликована: Янв. 1, 2023
With
formaldehyde
as
an
atom-economical
carbonyl
synthon,
the
EtOH-catalyzed
electrochemical
multicomponent
synthesis
of
various
imidazolidine-fused
sulfamidates
under
organic
oxidant-free,
energy-saving
and
mild
conditions
was
developed.
Advanced Synthesis & Catalysis,
Год журнала:
2021,
Номер
363(23), С. 5235 - 5265
Опубликована: Ноя. 4, 2021
Abstract
Hydrazones,
as
universal
structural
units,
are
useful
synthons
for
the
formation
of
carbon–nitrogen
and
nitrogen−heteroatom
bonds.
Thus,
they
provide
new
methods
constructing
nitrogen‐containing
heterocycles.
In
recent
years,
especially
between
2017
2021,
many
efforts
have
been
made
to
exploit
hydrazone‐based
reactions
in
develop
more
powerful
effective
pathways
towards
synthesis
various
multifunctional
heterocyclic
compounds.
However,
despite
tremendous
amount
work
that
has
published
over
past
five
no
review
summarizes
significant
progress
preparation
nitrogen
heterocycles
via
intramolecular
cyclization
hydrazones
with
adjacent
unsaturated
bonds
or
intermolecular
systems.
Therefore,
this
strategies
used
synthesize
years.
It
discusses
corresponding
reaction
scopes,
limitations,
mechanisms,
problems.
magnified
image
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(6), С. 1220 - 1268
Опубликована: Янв. 22, 2024
Abstract
Elaborated
molecular
architectures,
specifically
those
bearing
one
or
more
carbon
stereocenters,
stand
as
an
important
class
of
carbocyclic
and
heterocyclic
frameworks
because
they
are
frequently
occurring
core
structures
in
numerous
natural
products
biologically
active
pharmaceutical
molecules.
Over
the
past
few
decades,
development
versatile
synthetic
approaches
via
cascade
cyclization
reactions
1,6‐enynes
for
construction
a
series
fused
spiro
compounds
has
been
focus
great
deal
research
initiatives.
These
synthesis
strategies
peculiarly
fascinating
context
assembly
wide
array
molecules,
products,
agrochemicals,
functional
materials.
In
this
review,
recent
developments
transformations
with
diverse
coupling
reagents
summarized
since
2018,
which
could
be
divided
into
five
categories:
1)
Introduction;
2)
Transition
metal
catalyzed
1,6‐enynes;
3)
Metal‐free
4)
Visible‐light‐induced
5)
Electrocatalytic
1,6‐enynes.
