Chemistry - An Asian Journal,
Год журнала:
2021,
Номер
16(20), С. 3068 - 3081
Опубликована: Авг. 23, 2021
Abstract
2‐Pyrrolidones
have
aroused
enormous
interest
as
a
useful
structural
moiety
in
drug
discovery;
however,
not
only
does
their
syntheses
suffer
from
low
selectivity
and
yield,
but
also
it
requires
high
catalyst
loadings.
The
radical
cyclization
of
1,
n
‐enynes
‐dienes
has
demonstrated
to
be
an
attractive
method
for
the
synthesis
2‐pyrrolidones
due
its
mild
reaction
conditions,
fewer
steps,
higher
atom
economy,
excellent
functional
group
compatibility,
regioselectivity.
Furthermore,
receptors
with
unsaturated
bonds
(i.
e.
‐dienes)
play
crucial
role
realizing
because
ability
selectively
introduce
one
or
more
sources.
In
this
review,
we
discuss
representative
examples
methods
involving
published
last
five
years
each
prominent
design
mechanism,
providing
favorable
tools
valuable
2‐pyrrolidone
variety
applications.
Organic Chemistry Frontiers,
Год журнала:
2021,
Номер
8(19), С. 5403 - 5409
Опубликована: Янв. 1, 2021
A
visible-light
photoredox-catalyzed
four
component
reaction
of
quinoxalin-2(1
H
)-ones,
alkenes,
aryldiazonium,
and
sodium
metabisulfite
leading
to
sulfone-containing
)-ones
has
been
developed.
ACS Omega,
Год журнала:
2022,
Номер
7(44), С. 39531 - 39561
Опубликована: Окт. 27, 2022
Sulfonyl
hydrazides
are
viewed
as
alternatives
to
sulfinic
acids
and
their
salts
or
sulfonyl
halides,
which
broadly
used
in
organic
synthesis
work
active
pharmaceutical
substances.
Generally,
considered
good
building
blocks
show
powerful
value
a
diverse
range
of
reactions
construct
C–S
bonds
C–C
bonds,
even
C–N
sulfur,
carbon,
nitrogen
sources,
respectively.
As
profound
synthetic
tool,
the
electrosynthesis
method
was
recently
achieve
efficient
green
applications
hydrazides.
Interestingly,
many
unique
novel
electrochemical
syntheses
using
radical
precursors
have
been
developed,
including
cascade
reactions,
functionalization
heterocycles,
well
continuous
flow
combining
with
since
2017.
Accordingly,
it
is
necessary
specifically
summarize
recent
developments
only
more
deeply
understand
better
design
reactions.
Herein,
research
2017
reviewed
detail
based
on
chemical
structures
products
reaction
mechanisms.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
10(2), С. 570 - 589
Опубликована: Дек. 10, 2022
We
provide
a
comprehensive
overview
of
recent
progress
in
this
rapidly
growing
field
by
summarizing
catalytic
annulation
reactions
ortho
-alkynyl
aryl
ketones
which
involve
carbo-
and
oxo
-cyclization
patterns
with
consideration
their
mechanisms
applications.
Chemical Communications,
Год журнала:
2022,
Номер
58(74), С. 10420 - 10423
Опубликована: Янв. 1, 2022
A
new
electrochemical
selective
annulative
amino-ketalization
and
amino-oxygenation
of
1,6-enynes
with
disulfonimides
alcohols
is
reported,
producing
a
series
functionalized
benzofurans
under
catalyst-
oxidant-free
conditions.
