Mini-Reviews in Organic Chemistry, Год журнала: 2022, Номер 20(3), С. 285 - 308

Опубликована: Май 11, 2022

Abstract: Compounds containing a C=N moiety, namely imines, have been widely used for industrial purposes due to their various biological activities. Cyclic imines are an essential class of nitrogen-based heterocycles and valuable scaffolds designing obtaining new biologically active compounds. However, the proposal implementation synthetic methods this heterocyclic system mainly conditioned by different structural stereoelectronic considerations. Therefore, it can be complex sometimes limited selected group The following review paper is structured search collect synthesis cyclic identify main progress currently achieved. It addresses topic using considerations, physical properties, reactivity. described below implemented strategies based on cyclo-condensation reactions, radical cyclizations, electrocyclic closures, carbon-carbon coupling metal-organic catalysis. These significantly contributed organic chemistry knowledge. In addition, analysis such from applying principles green circular presented, evaluating potential application these methods, limitations, perspectives, impact environment.

Язык: Английский