Asian Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 27, 2024
Abstract
With
Ag/g‐C
3
N
4
semiconductor
as
the
heterogeneous
photocatalyst,
visible
light
promoted
synthesis
of
unsymmetric
diaryl
chalcogenides
could
be
achieved
under
additive‐free
and
mild
conditions.
A
series
were
generated
in
good
to
excellent
yields
with
high
functional
group
tolerance.
The
photocatalyst
is
easily
recovered
from
reaction
mixture
reused
at
least
5
times,
opening
way
for
larger‐scale
industrial
applications
this
type
photocatalytic
bond‐forming
reactions.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 9, 2025
In
this
study,
a
novel
approach
that
combines
photoinduced
electron
transfer
(ET)
with
hydrogen
atom
(HAT)
has
been
introduced
for
the
selective
β-C(sp3)–H
pyridination
of
carbonyl
compounds.
This
method
is
notable
its
absence
transition
metals
and
ability
to
function
under
benign
reaction
conditions,
resulting
in
range
pyridinated
derivatives
consistently
moderate
good
yields.
The
significance
technique
further
underscored
by
potential
late-stage
functionalization
pharmaceutically
significant
molecules.
Mechanistic
investigations
confirmed
proceeds
via
radical-mediated
pathway.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
90(4), С. 1683 - 1696
Опубликована: Янв. 17, 2025
In
the
vanguard
of
sustainable
chemistry,
pursuit
efficient
pathways
for
synthesis
alkyl
bicyclo[1.1.1]pentane-heteroaryls
has
captured
attention
scientific
vanguard.
We
herein
report
a
groundbreaking
and
eco-conscious
multicomponent
coupling
reaction
that
paves
way
alkylation
heteroarylation
[1.1.1]propellane,
process
uniquely
enabled
by
photochemical
prowess
an
electron
donor–acceptor
(EDA)
complex.
This
method
is
distinguished
its
minimalist
yet
powerful
approach:
devoid
transition
metals,
additives,
photosensitizers.
Its
universality
further
exemplified
seamless
compatibility
broad
spectrum
halides
heteroarenes
under
standardized
conditions,
heralding
new
era
synthetic
versatility.
The
method's
practicality
underscored
capacity
late-stage
modification
pharmaceuticals,
offering
transformative
tool
enhancement
existing
drug
molecules.
Moreover,
facile
derivatization
synthesized
products
underscores
adaptability
potential
diverse
applications.
Our
mechanistic
studies
have
elucidated
underlying
radical-relay
pathway,
pinpointing
pivotal
role
EDA
complex
in
initiating
transformation.
discovery
not
only
enriches
our
fundamental
understanding
but
also
opens
avenues
strategic
optimization.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(18), С. 5278 - 5305
Опубликована: Янв. 1, 2024
This
review
summarizes
the
latest
methodological
advances
in
photocatalytic
C(sp
3
)–H
functionalization,
with
a
particular
emphasis
on
formation
of
C–P,
C–B,
C–S
bonds,
etc
.,
and
some
prominent
efforts
asymmetric
C–H
functionalization.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(14), С. 4024 - 4040
Опубликована: Янв. 1, 2024
This
review
provides
a
comprehensive
overview
of
metal
catalysis
in
photo-electrochemical
systems,
discussing
reaction
mechanisms
and
offering
prospects
for
this
triadic
catalytic
mode.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
This
study
describes
a
pioneering
visible-light-induced
phosphine-catalyzed
halogen-atom
transfer
(XAT)
strategy
that
heralds
new
era
in
the
difunctionalization
of
[1.1.1]propellane.
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(13), С. 2898 - 2918
Опубликована: Май 18, 2024
Abstract
Converting
any
desired
C−H
bond
to
the
intended
C−Z
in
a
given
organic
molecule
could
be
final
peak
of
functionalization
methodology.
Among
three
types
bonds,
ubiquitous
C(
sp
3
)−H
has
gained
particular
attention,
especially
last
two
decades.
There
are
different
ways
transform
bonds
into
bonds.
The
use
chlorine
radicals
is
one
these
methods
with
promising
future.
literature
review
shows
that
sources
have
been
used
for
chlorine,
including
chloride
ions
(HCl
or
salts),
coordinated
chlorides
(transition
metal
complexes),
and
(organochlorine
compounds).
However,
HCl
FeCl
most
attention
among
sources.
major
convert
from
radicals:
1)
oxidation
hydrogen
salts,
2)
photolysis
chloride,
3)
transition
insertion
C−Cl
This
summarizes
published
research
papers
on
functionalization.
Therefore,
chlorination
reactions
which
do
not
play
direct
role
cleavage
within
scope
this
review.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(32), С. 22172 - 22179
Опубликована: Июль 30, 2024
The
strategic
integration
of
organocatalysis
with
transition-metal
catalysis
to
achieve
otherwise
unattainable
stereoselective
transformations
may
serve
as
a
powerful
synthetic
tool.
Herein,
we
present
synthetically
versatile
α-amidation
aldehydes
by
leveraging
dual
iron
and
chiral
enamine
in
an
enantioselective
manner
(up
>99:1
er).
Experimental
computational
studies
have
led
us
propose
new
mechanistic
platform,
wherein
visible-light-promoted
LMCT
generates
[Fe(II)Cl
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(33), С. 6650 - 6664
Опубликована: Янв. 1, 2024
Titanium,
as
an
important
transition
metal,
has
garnered
extensive
attention
in
both
industry
and
academia
due
to
its
excellent
mechanical
properties,
corrosion
resistance,
unique
reactivity
organic
synthesis.
In
the
field
of
photocatalysis,
titanium-based
compounds
such
titanium
dioxide
(TiO
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Окт. 4, 2024
The
challenging
synthesis
of
thermodynamic-unfavored
cis-olefins
through
catalytic
cross-coupling
reactions
requires
the
synergistic
interaction
substrate-activating
units
and
configuration-regulating
catalysts.
Successfully
hitting
these
two
birds
with
one
stone,
we
herein
develop
a
convenient
photoredox
access
to
Z-alkenes
from
alkynes
light
alkanes
bifunctional
iron-catalyzed
system
possessing
both
C(sp
