Nickel-catalysed highly regioselective synthesis of β-acyl naphthalenes under reductive conditions
Yujuan Wu,
Chen Ma,
Jia-Fan Qiao
и другие.
Chemical Communications,
Год журнала:
2024,
Номер
60(44), С. 5723 - 5726
Опубликована: Янв. 1, 2024
A
nickel-catalysed
reductive
ring-opening
reaction
of
7-oxabenzonorbornadienes
with
acyl
chlorides
as
the
electrophilic
coupling
partner
was
developed,
generating
β-acyl
naphthalene
unique
product
without
any
α
iso.
Язык: Английский
Magnesium-promoted nickel-catalysed chlorination of aryl halides and triflates under mild conditions
Chemical Communications,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Nickel-catalysed
chlorination
of
aryl
halides
and
triflates
has
been
developed
with
magnesium
chloride,
which
promoted
the
challenging
reductive
elimination
from
Ni(
ii
)
intermediates.
Язык: Английский
Nickel-Catalyzed Reductive Cyanation of Aryl Halides and Epoxides with Cyanogen Bromide
Molecules,
Год журнала:
2024,
Номер
29(24), С. 6016 - 6016
Опубликована: Дек. 20, 2024
Nitriles
are
valuable
compounds
because
they
have
widespread
applications
in
organic
chemistry.
This
report
details
the
nickel-catalyzed
reductive
cyanation
of
aryl
halides
and
epoxides
with
cyanogen
bromide
for
synthesis
nitriles.
robust
protocol
underscores
practicality
using
a
commercially
available
cost-effective
reagent.
A
variety
featuring
diverse
functional
groups,
such
as
-TMS,
-Bpin,
-OH,
-NH2,
-CN,
-CHO,
were
successfully
converted
into
nitriles
moderate-to-good
yields.
Moreover,
syntheses
at
gram-scale
application
late-stage
natural
products
drugs
reinforces
its
potentiality.
Язык: Английский
Collaborative Reduction-Induced Nickel-Catalytic Selective C–S Coupling of Aryl Di/Trithiosulfonates with Aryl Halides
Organic Letters,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 25, 2024
Metal-catalytic
conversion
of
polysulfide
reagents
is
a
major
challenge
in
organic
synthesis
due
to
its
challenging
activation
modes
multiple
S–S
bonds.
The
utilization
aryl
di-
and
trithiosulfonates
nickel-catalyzed
reductive
coupling
with
halides
has
been
unexplored.
Herein,
we
unprecedentedly
describe
PPh3
Zn-collaborative
reduction-induced
nickel-catalytic
selective
C–S
di/trithiosulfonates
access
sulfides
over
common
disulfides
or
trisulfides.
Diverse
mechanistic
studies
indicate
that
the
key
design
such
reaction
could
be
attributed
employment
MgCl2,
which
collaborate
Zn
for
improved
reduction
potential
enables
cleavage
PhSO2(S)naryl
(n
=
2,
3)
electrophilic
sulfur
species
sulfuration
controllable
fashion.
Язык: Английский
Benzothiazolium Salts as Versatile Primary Alcohol Derivatives in Ni-Catalyzed Cross-Electrophile Arylation/Vinylation
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 31, 2024
A
Ni-catalyzed
cross-electrophile
coupling
of
aryl/vinyl
halides
with
benzothiazolium
salts
derived
from
alcohols
is
presented.
Язык: Английский