Ionic liquid coordinated metal-catalyzed organic transformations: A comprehensive review

Coordination Chemistry Reviews, Год журнала: 2022, Номер 472, С. 214769 - 214769

Опубликована: Авг. 19, 2022

Язык: Английский

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Maleimides in Directing‐Group‐Controlled Transition‐Metal‐Catalyzed Selective C−H Alkylation

European Journal of Organic Chemistry, Год журнала: 2021, Номер 2021(43), С. 5862 - 5879

Опубликована: Окт. 20, 2021

Abstract Maleimides and succinimides are all vital scaffolds in biological fields various natural products. Maleimide derivatives have been extensively used as coupling partners for organic transformations, affording a broad array of important molecular architectures including succinimides. In the past decade, variety efficient chelation‐assisted strategies employed selective addition C−H bonds to maleimides giving succinimides, which also highly building blocks synthesis. This Review provides an overview research progress relating participated transition‐metal‐catalyzed group‐directed alkylation from 2012 2021. Significant advances this field were highlighted, diverse transition metal catalysts, substrates contained different directing groups, reaction mechanisms well synthetic applications systematically discussed. addition, limitations intractable issues need be solved future pointed out.

Язык: Английский

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Deaminative meta-C–H alkylation by ruthenium(ii) catalysis

Chemical Science, Год журнала: 2021, Номер 12(23), С. 8073 - 8078

Опубликована: Янв. 1, 2021

Precise structural modifications of amino acids are importance to tune biological properties or modify therapeutical capabilities relevant drug discovery.

Язык: Английский

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Looking deep into C–H functionalization: the synthesis and application of cyclopentadienyl and related metal catalysts

Chemical Communications, Год журнала: 2022, Номер 58(19), С. 3101 - 3121

Опубликована: Янв. 1, 2022

This feature review is focused on recent key applications of commonly used transition-metal Cp-type catalysts for C–H bond functionalizations.

Язык: Английский

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Ruthenium-Catalyzed Dehydrogenative Functionalization of Alcohols to Pyrroles: A Comparison between Metal–Ligand Cooperative and Non-cooperative Approaches

The Journal of Organic Chemistry, Год журнала: 2022, Номер 87(11), С. 7106 - 7123

Опубликована: Май 18, 2022

Herein, we report the synthesis and characterization of two ruthenium-based pincer-type catalysts, [1]X (X = Cl, PF6) 2, containing different tridentate pincer ligands, 2-pyrazolyl-(1,10-phenanthroline) (L1) 2-arylazo-(1,10-phenanthroline) (L2a/2b, L2a 2-(phenyldiazenyl)-1,10-phenanthroline; L2b 2-((4-chlorophenyl)diazenyl)-1,10-phenanthroline), their application in substituted pyrroles via dehydrogenative alcohol functionalization reactions. In catalyst PF6), scaffold is apparently redox innocent, all events occur at metal center, coordinated ligands remain as spectators. contrast, catalysts 2a 2b, azo-aromatic scaffolds are highly redox-active known to participate actively during dehydrogenation alcohols. A comparison between catalytic activities these was made, starting from simple alcohols further various understand advantages/disadvantages metal-ligand cooperative approach. Various were prepared coupling secondary amino alcohols, N-substituted synthesized aromatic amines with cis-2-butene-1,4-diol 2-butyne-1,4-diol, respectively. Several control reactions spectroscopic experiments performed characterize establish reaction mechanism.

Язык: Английский

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Ruthenium‐Catalyzed Direct Reductive Amination of Carbonyl Compounds for the Synthesis of Amines: An Overview

European Journal of Organic Chemistry, Год журнала: 2023, Номер 26(15)

Опубликована: Фев. 14, 2023

Abstract Reductive amination is a valuable method for amine synthesis that has been the topic of century‘s worth in‐depth study in both academia and industry. Amines their derivatives serve as incredibly adaptable building blocks broad array organic substrates are significant precursors myriad advanced chemicals, physiologically active compounds, agrochemicals, biomolecules, pharmaceuticals, polymers. The creation innovative catalytic processes long‐term selective amines from readily accessible environmentally benign reagents remains top priority chemical research. Both heterogeneous homogeneous catalysts have designed with success to enable these reactions explore new amines. Ruthenium employed reductive owing stability, selectivity, versatility, low toxicity, high efficiency. This review comprehensively overviews Ru‐catalyzed includes literature 2009 2022.

Язык: Английский

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Redox-neutral C–H annulation strategies for the synthesis of heterocycles via high-valent Cp*Co(iii) catalysis

Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 21(19), С. 3918 - 3941

Опубликована: Янв. 1, 2023

This review demonstrates the redox-neutral synthetic approaches towards valuable heterocycles such as isoquinolines, indoles, isoquinolones, and tetrahydroquinolines via high-valent Cp*Co( iii ) catalysis.

Язык: Английский

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Ni/NHC catalysis in C–H functionalization using air-tolerant nickelocene and sodium formate for in situ catalyst generation

Organic Chemistry Frontiers, Год журнала: 2021, Номер 8(11), С. 2515 - 2524

Опубликована: Янв. 1, 2021

A facile method for Ni/NHC catalyzed C–H alkylation and alkenylation of heteroarenes with alkenes internal alkynes using air-tolerant nickelocene, sodium formate NHC·HCl salts in situ catalyst generation has been developed.

Язык: Английский

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Photoinduced ruthenium-catalyzed alkyl-alkyl cross-coupling reactions

Chem Catalysis, Год журнала: 2021, Номер 1(2), С. 467 - 479

Опубликована: Май 24, 2021

Язык: Английский

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Enaminone-directed ruthenium(ii)-catalyzed C–H activation and annulation of arenes with diazonaphthoquinones for polycyclic benzocoumarins

Chemical Communications, Год журнала: 2023, Номер 59(88), С. 13187 - 13190

Опубликована: Янв. 1, 2023

Weakly coordinating enaminone functionality has been leveraged for C–H activation strategy under ruthenium catalysis the regioselective annulative coupling of arenes with diazonaphthoquinones, offering polycyclic benzocoumarins in high yields.

Язык: Английский

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