Research progress on carbon materials in tumor photothermal therapy DOI Open Access
Kezhen Qi, Bin Sun, Shuyuan Liu

и другие.

Biomedicine & Pharmacotherapy, Год журнала: 2023, Номер 165, С. 115070 - 115070

Опубликована: Июнь 28, 2023

At present, cancer remains one of the leading causes human death worldwide, and surgery, radiotherapy chemotherapy are still main methods treatment. However, these treatments have their drawbacks. Surgical treatment often struggles with complete removal tumor tissue, to a high risk recurrence. Additionally, drugs significant impact on overall health can easily result in drug resistance. The mortality other reasons promote scientific researchers unremittingly develop find more accurate faster diagnosis strategy effective method. Photothermal therapy, which utilizes near-infrared light, offers deeper tissue penetration minimal damage surrounding healthy tissues. Compared conventional methods, photothermal therapy boasts several advantages, including efficiency, non-invasiveness, simplicity, toxicity, fewer side effects. nanomaterials be categorized as either organic or inorganic materials. This review primarily focuses behavior carbon materials role Furthermore, challenges faced by discussed.

Язык: Английский

Carbon Dot‐Based Hydrogels: Preparations, Properties, and Applications DOI
Yijie Wang,

Tingjie Lv,

Keyang Yin

и другие.

Small, Год журнала: 2023, Номер 19(17)

Опубликована: Янв. 29, 2023

Hydrogels have extremely high moisture content, which makes it very soft and excellently biocompatible. They become an important material a wide range of applications in various fields such as biomedicine, bionic smart material, electrochemistry. Carbon dot (CD)-based hydrogels are based on carbon dots (CDs) auxiliary substances, forming gel with comprehensive properties individual components. CDs embedding could not only solve their aggregation-caused quenching (ACQ) effect, but also manipulate the even bring some novel properties, achieving win-win situation. In this review, preparation methods, formation mechanism, CD-based hydrogels, sensing, adsorption, energy storage, catalysis -are summarized. Finally, brief discussion future research directions will be given.

Язык: Английский

Процитировано

70

Polymer–Structure‐Induced Room‐Temperature Phosphorescence of Carbon Dot Materials DOI Creative Commons
Chengyu Zheng,

Songyuan Tao,

Bai Yang

и другие.

Small Structures, Год журнала: 2023, Номер 4(5)

Опубликована: Фев. 2, 2023

As emerging carbon‐based nanomaterials, carbon dots (CDs) are widely studied with regard to their luminescent properties. CDs obtained by the bottom‐up method exhibit polymeric characteristics after crosslinking, polymerization, and incomplete carbonization processes, herein referred as carbonized polymer (CPDs). In recent years, large progress has been achieved on room‐temperature phosphorescence (RTP) properties of CPDs. The developments synthesis strategies for RTP CPD materials reviewed. However, less attention devoted influence structures materials. Polymer a common feature extensive key factors facilitating Herein, effects emission self‐protective matrix‐assisted discussed. It is considered that can effectively immobilize subluminophores protect triplet excited states facilitate crosslink‐enhanced (CEE) effect proposed further explain materials, which provide an effective strategy Benefiting from CEE effect, efficient be applications then briefly summarized.

Язык: Английский

Процитировано

63

In Situ Coupling of Carbon Dots with Co‐ZIF Nanoarrays Enabling Highly Efficient Oxygen Evolution Electrocatalysis DOI Creative Commons

Hong Qiang,

Yingming Wang, Ruirui Wang

и другие.

Small, Год журнала: 2023, Номер 19(31)

Опубликована: Янв. 2, 2023

Metal-organic frameworks (MOFs) are regarded as one promising class of precatalysts for electrocatalytic oxygen evolution reaction (OER), yet most them suffer from poor conductivity and lack coordinatively unsaturated metal sites, which hinders the fast electrochemical reconstruction thus a OER activity. To address this issue, unique heterocomposite has been constructed by in situ inserting carbon dots (CDs) into cobalt-based zeolitic imidazolate framework (Co-ZIF) nanosheet arrays (Co-ZIF/CDs/CC) presence cloth (CC) via one-pot coprecipitation alkaline OER. Benefiting synergism between CDs Co-ZIF subunits such superior conductivity, strong charge interaction well abundant sites exposure, Co-ZIF/CDs/CC exhibits an enhanced promotion effect contributes to deep phase transformation CDs-coupled active CoOOH. As expected, achieved only requires overpotential 226 mV deliver 10 mA cm-2 1.0 M KOH, is lower than that Co-ZIF/CC previously reported CC-supported MOF precatalysts. Moreover, it can also maintain large current density 100 24 h with negligible activity decay.

Язык: Английский

Процитировано

61

A Metal‐Free Mesoporous Carbon Dots/Silica Hybrid Type I Photosensitizer with Enzyme‐Activity for Synergistic Treatment of Hypoxic Tumor DOI
Boshi Tian, Shaohua Liu, Chenghao Yu

и другие.

Advanced Functional Materials, Год журнала: 2023, Номер 33(25)

Опубликована: Март 10, 2023

Abstract As a less O 2 ‐dependent photodynamic therapy (PDT), type I PDT is an effective approach to overcome the hypoxia‐induced low efficiency against solid tumors. However, commonly used metal‐involved agents suffer from long‐term biosafety concern. Herein, metal‐free photosensitizer, N ‐doped carbon dots/mesoporous silica nanoparticles (NCDs/MSN, ≈40 nm) nanohybrid with peroxidase (POD)‐like activity for synergistic and enzyme‐activity treatment, developed on gram scale via facile one‐pot strategy through mixing source precursor assistance of template. Benefiting narrow bandgap (1.92 eV) good charge separation capacity NCDs/MSN, upon 640 nm light irradiation, excited electrons in conduction band can effectively generate •− by reduction dissolved one‐electron transfer process even under hypoxic conditions, inducing apoptosis tumor cells. Moreover, photoinduced partially transform into more toxic • OH two‐electron reduction. POD‐like NCDs/MSN catalyze endogenous H microenvironment, further synergistically ablating 4T1 Therefore, mass production way synthesize novel photosensitizer enzyme‐mimic treatment tumors provided, which exhibits promising clinical translation prospects.

Язык: Английский

Процитировано

57

Research progress on carbon materials in tumor photothermal therapy DOI Open Access
Kezhen Qi, Bin Sun, Shuyuan Liu

и другие.

Biomedicine & Pharmacotherapy, Год журнала: 2023, Номер 165, С. 115070 - 115070

Опубликована: Июнь 28, 2023

At present, cancer remains one of the leading causes human death worldwide, and surgery, radiotherapy chemotherapy are still main methods treatment. However, these treatments have their drawbacks. Surgical treatment often struggles with complete removal tumor tissue, to a high risk recurrence. Additionally, drugs significant impact on overall health can easily result in drug resistance. The mortality other reasons promote scientific researchers unremittingly develop find more accurate faster diagnosis strategy effective method. Photothermal therapy, which utilizes near-infrared light, offers deeper tissue penetration minimal damage surrounding healthy tissues. Compared conventional methods, photothermal therapy boasts several advantages, including efficiency, non-invasiveness, simplicity, toxicity, fewer side effects. nanomaterials be categorized as either organic or inorganic materials. This review primarily focuses behavior carbon materials role Furthermore, challenges faced by discussed.

Язык: Английский

Процитировано

53