Biomedicine & Pharmacotherapy,
Год журнала:
2023,
Номер
165, С. 115070 - 115070
Опубликована: Июнь 28, 2023
At
present,
cancer
remains
one
of
the
leading
causes
human
death
worldwide,
and
surgery,
radiotherapy
chemotherapy
are
still
main
methods
treatment.
However,
these
treatments
have
their
drawbacks.
Surgical
treatment
often
struggles
with
complete
removal
tumor
tissue,
to
a
high
risk
recurrence.
Additionally,
drugs
significant
impact
on
overall
health
can
easily
result
in
drug
resistance.
The
mortality
other
reasons
promote
scientific
researchers
unremittingly
develop
find
more
accurate
faster
diagnosis
strategy
effective
method.
Photothermal
therapy,
which
utilizes
near-infrared
light,
offers
deeper
tissue
penetration
minimal
damage
surrounding
healthy
tissues.
Compared
conventional
methods,
photothermal
therapy
boasts
several
advantages,
including
efficiency,
non-invasiveness,
simplicity,
toxicity,
fewer
side
effects.
nanomaterials
be
categorized
as
either
organic
or
inorganic
materials.
This
review
primarily
focuses
behavior
carbon
materials
role
Furthermore,
challenges
faced
by
discussed.
Hydrogels
have
extremely
high
moisture
content,
which
makes
it
very
soft
and
excellently
biocompatible.
They
become
an
important
material
a
wide
range
of
applications
in
various
fields
such
as
biomedicine,
bionic
smart
material,
electrochemistry.
Carbon
dot
(CD)-based
hydrogels
are
based
on
carbon
dots
(CDs)
auxiliary
substances,
forming
gel
with
comprehensive
properties
individual
components.
CDs
embedding
could
not
only
solve
their
aggregation-caused
quenching
(ACQ)
effect,
but
also
manipulate
the
even
bring
some
novel
properties,
achieving
win-win
situation.
In
this
review,
preparation
methods,
formation
mechanism,
CD-based
hydrogels,
sensing,
adsorption,
energy
storage,
catalysis
-are
summarized.
Finally,
brief
discussion
future
research
directions
will
be
given.
As
emerging
carbon‐based
nanomaterials,
carbon
dots
(CDs)
are
widely
studied
with
regard
to
their
luminescent
properties.
CDs
obtained
by
the
bottom‐up
method
exhibit
polymeric
characteristics
after
crosslinking,
polymerization,
and
incomplete
carbonization
processes,
herein
referred
as
carbonized
polymer
(CPDs).
In
recent
years,
large
progress
has
been
achieved
on
room‐temperature
phosphorescence
(RTP)
properties
of
CPDs.
The
developments
synthesis
strategies
for
RTP
CPD
materials
reviewed.
However,
less
attention
devoted
influence
structures
materials.
Polymer
a
common
feature
extensive
key
factors
facilitating
Herein,
effects
emission
self‐protective
matrix‐assisted
discussed.
It
is
considered
that
can
effectively
immobilize
subluminophores
protect
triplet
excited
states
facilitate
crosslink‐enhanced
(CEE)
effect
proposed
further
explain
materials,
which
provide
an
effective
strategy
Benefiting
from
CEE
effect,
efficient
be
applications
then
briefly
summarized.
Metal-organic
frameworks
(MOFs)
are
regarded
as
one
promising
class
of
precatalysts
for
electrocatalytic
oxygen
evolution
reaction
(OER),
yet
most
them
suffer
from
poor
conductivity
and
lack
coordinatively
unsaturated
metal
sites,
which
hinders
the
fast
electrochemical
reconstruction
thus
a
OER
activity.
To
address
this
issue,
unique
heterocomposite
has
been
constructed
by
in
situ
inserting
carbon
dots
(CDs)
into
cobalt-based
zeolitic
imidazolate
framework
(Co-ZIF)
nanosheet
arrays
(Co-ZIF/CDs/CC)
presence
cloth
(CC)
via
one-pot
coprecipitation
alkaline
OER.
Benefiting
synergism
between
CDs
Co-ZIF
subunits
such
superior
conductivity,
strong
charge
interaction
well
abundant
sites
exposure,
Co-ZIF/CDs/CC
exhibits
an
enhanced
promotion
effect
contributes
to
deep
phase
transformation
CDs-coupled
active
CoOOH.
As
expected,
achieved
only
requires
overpotential
226
mV
deliver
10
mA
cm-2
1.0
M
KOH,
is
lower
than
that
Co-ZIF/CC
previously
reported
CC-supported
MOF
precatalysts.
Moreover,
it
can
also
maintain
large
current
density
100
24
h
with
negligible
activity
decay.
Advanced Functional Materials,
Год журнала:
2023,
Номер
33(25)
Опубликована: Март 10, 2023
Abstract
As
a
less
O
2
‐dependent
photodynamic
therapy
(PDT),
type
I
PDT
is
an
effective
approach
to
overcome
the
hypoxia‐induced
low
efficiency
against
solid
tumors.
However,
commonly
used
metal‐involved
agents
suffer
from
long‐term
biosafety
concern.
Herein,
metal‐free
photosensitizer,
N
‐doped
carbon
dots/mesoporous
silica
nanoparticles
(NCDs/MSN,
≈40
nm)
nanohybrid
with
peroxidase
(POD)‐like
activity
for
synergistic
and
enzyme‐activity
treatment,
developed
on
gram
scale
via
facile
one‐pot
strategy
through
mixing
source
precursor
assistance
of
template.
Benefiting
narrow
bandgap
(1.92
eV)
good
charge
separation
capacity
NCDs/MSN,
upon
640
nm
light
irradiation,
excited
electrons
in
conduction
band
can
effectively
generate
•−
by
reduction
dissolved
one‐electron
transfer
process
even
under
hypoxic
conditions,
inducing
apoptosis
tumor
cells.
Moreover,
photoinduced
partially
transform
into
more
toxic
•
OH
two‐electron
reduction.
POD‐like
NCDs/MSN
catalyze
endogenous
H
microenvironment,
further
synergistically
ablating
4T1
Therefore,
mass
production
way
synthesize
novel
photosensitizer
enzyme‐mimic
treatment
tumors
provided,
which
exhibits
promising
clinical
translation
prospects.
Biomedicine & Pharmacotherapy,
Год журнала:
2023,
Номер
165, С. 115070 - 115070
Опубликована: Июнь 28, 2023
At
present,
cancer
remains
one
of
the
leading
causes
human
death
worldwide,
and
surgery,
radiotherapy
chemotherapy
are
still
main
methods
treatment.
However,
these
treatments
have
their
drawbacks.
Surgical
treatment
often
struggles
with
complete
removal
tumor
tissue,
to
a
high
risk
recurrence.
Additionally,
drugs
significant
impact
on
overall
health
can
easily
result
in
drug
resistance.
The
mortality
other
reasons
promote
scientific
researchers
unremittingly
develop
find
more
accurate
faster
diagnosis
strategy
effective
method.
Photothermal
therapy,
which
utilizes
near-infrared
light,
offers
deeper
tissue
penetration
minimal
damage
surrounding
healthy
tissues.
Compared
conventional
methods,
photothermal
therapy
boasts
several
advantages,
including
efficiency,
non-invasiveness,
simplicity,
toxicity,
fewer
side
effects.
nanomaterials
be
categorized
as
either
organic
or
inorganic
materials.
This
review
primarily
focuses
behavior
carbon
materials
role
Furthermore,
challenges
faced
by
discussed.