Photothermal antibacterial materials to promote wound healing

Journal of Controlled Release, Год журнала: 2023, Номер 363, С. 180 - 200

Опубликована: Сен. 27, 2023

Язык: Английский

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Janus Nanofiber Membranes with Photothermal‐Enhanced Biofluid Drainage and Sterilization for Diabetic Wounds

Advanced Functional Materials, Год журнала: 2024, Номер 34(24)

Опубликована: Фев. 16, 2024

Abstract Diabetic wounds are difficult to heal, and the key wound healing is exudate management effective disinfection. Inspired by asymmetric wettability of Janus‐structured lotus leaves, herein study has presented design a biomimetic Janus membrane that integrates unidirectional biofluid drainage photothermal‐enhanced evaporation/sterilization capabilities for accelerating diabetic healing. This prepared electrospinning polyacrylonitrile (PAN) nanofiber containing polydopamine (PDA) on surface polypropylene (PP) nonwoven membrane. Such PP/PAN x%PDA enables antigravity “pumping” water from hydrophobic PP layer hydrophilic PAN within 22 s through contact points interface. The incorporation 30 wt% PDA in imparts high photoabsorption photothermal responsiveness, facilitating continuous volatilization exudate, achieving twice displacement water, causing irreversible damage bacteria. As result, it effectively alleviates inflammation cellular fibrosis while promoting collagen deposition due its structure antibacterial properties. Impressively, such achieves an impressive closure rate 96.7% wounds, better than (59.8%) conventional bandages. Therefore, this offers promising alternative chronic wounds.

Язык: Английский

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Current advances in metal–organic frameworks for cancer nanodynamic therapies

Coordination Chemistry Reviews, Год журнала: 2023, Номер 497, С. 215434 - 215434

Опубликована: Сен. 17, 2023

Язык: Английский

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Progress in nanomaterial-based synergistic photothermal-enhanced chemodynamic therapy in combating bacterial infections

Progress in Materials Science, Год журнала: 2024, Номер 144, С. 101292 - 101292

Опубликована: Апрель 6, 2024

The prevalence of multidrug-resistant (MDR) bacterial infections has emerged as a serious threat to clinical treatment and global human health, become one the most important challenges in therapy. Hence, there is an urgent need develop safe, effective, new antibacterial strategies based on multifunctional nanomaterials for accurate detection MDR infections. Chemodynamic therapy (CDT) emerging therapeutic strategy that uses Fenton/Fenton-like metal-based nanocatalysts convert hydrogen peroxide (H2O2) into hydroxyl radicals (OH) destroy Despite enormous potential CDT, single CDT limitations such low catalytic efficacy insufficient production H2O2. In this regard, can be combined with other strategies, photothermal (PTT), which effectively enhanced by PTT heating effect. Thus, rational combination nanoplatform been demonstrated highly efficient achieving better This review summarizes discusses latest advances photothermal-enhanced (PT/CDT) infection theranostics well advantages, challenges, future research directions applications, will inspire development PT/CDT

Язык: Английский

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Tumor microenvironment sensitization via dual-catalysis of carbon-based nanoenzyme for enhanced photodynamic therapy

Journal of Colloid and Interface Science, Год журнала: 2024, Номер 663, С. 577 - 590

Опубликована: Фев. 21, 2024

Язык: Английский

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Polydopamine-based nanostructures: A new generation of versatile, multi-tasking, and smart theranostic tools

Nano Today, Год журнала: 2024, Номер 55, С. 102151 - 102151

Опубликована: Янв. 9, 2024

Smart nanomaterials, thanks to their stimuli-responsive properties, represent a promising class of nanostructures for biomedical applications. Their ability undergo structural or functional changes in response specific external cues has been exploited the manipulation cellular activities as potential treatment various health disorders. Despite rather interesting properties and applications, most smart are composed inorganic materials, thus limiting translatability clinical applications due toxicity long-term accumulation concerns. Polydopamine can overcome limitations posed by nanomaterials high biocompatibility, biodegradability, antioxidant effects, pH-responsiveness, tunability, surface reactivity, photothermal conversion act photoacoustic contrast agents. In this review, we will present general analysis polydopamine Our aim is provide reader with state art concerning use organic nanoplatforms nanomedicine, also providing an current connected translation solutions these challenges.

Язык: Английский

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Polydopamine interface-modulated MXene-based conductive antibacterial hydrogels for on-skin health monitoring and diabetic wound healing

Composites Part A Applied Science and Manufacturing, Год журнала: 2024, Номер 180, С. 108065 - 108065

Опубликована: Фев. 8, 2024

Язык: Английский

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Multifunctional dynamic chitosan-guar gum nanocomposite hydrogels in infection and diabetic wound healing

Carbohydrate Polymers, Год журнала: 2025, Номер unknown, С. 123316 - 123316

Опубликована: Янв. 1, 2025

Язык: Английский

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Optimized strategies of ROS-based nanodynamic therapies for tumor theranostics

Biomaterials, Год журнала: 2023, Номер 303, С. 122391 - 122391

Опубликована: Ноя. 15, 2023

Язык: Английский

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Advances and opportunities of polydopamine coating in biosensing: Preparation, functionality, and applications

Coordination Chemistry Reviews, Год журнала: 2023, Номер 501, С. 215564 - 215564

Опубликована: Дек. 1, 2023

Язык: Английский

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