Amphiphilic quinoline-malononitrile AIE probes: From molecule design to bio-applications

Coordination Chemistry Reviews, Год журнала: 2025, Номер 533, С. 216550 - 216550

Опубликована: Фев. 24, 2025

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Near-infrared fluorescent probe for detection of hydrogen sulfide in water samples and food spoilage

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2024, Номер 316, С. 124341 - 124341

Опубликована: Апрель 23, 2024

Язык: Английский

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Application of a fluorescent probe exhibiting a large stokes shift after the precise detection of hydrazine in plants, foods and living cells

Journal of Hazardous Materials, Год журнала: 2025, Номер 488, С. 137452 - 137452

Опубликована: Фев. 3, 2025

Язык: Английский

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Self-adaptive photodynamic therapy for boosting therapeutic efficiency in tumor

Science China Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 3, 2025

Язык: Английский

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A cyanine fluorophore for imaging-guided tumor photodynamic and photothermal therapy under NIR-II light activation

Science China Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 10, 2025

Язык: Английский

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Real-time monitoring and in vivo visualization of acetylcholinesterase activity with a near-infrared fluorescent probe

Journal of Pharmaceutical Analysis, Год журнала: 2025, Номер unknown, С. 101204 - 101204

Опубликована: Янв. 1, 2025

Язык: Английский

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Precise diabetes visualization designed for lipid droplet-targeted polarity-sensitive fluorescent probe

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113018 - 113018

Опубликована: Фев. 1, 2025

Язык: Английский

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In vitro and in vivo bioimaging by Quinoline conjugated probes and dyes

Coordination Chemistry Reviews, Год журнала: 2025, Номер 536, С. 216654 - 216654

Опубликована: Апрель 10, 2025

Язык: Английский

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The first specific probe for pyrrolidine with multifunction by the interaction mechanism of atomic economic reaction

iScience, Год журнала: 2024, Номер 27(7), С. 110024 - 110024

Опубликована: Май 18, 2024

Pyrrolidine (PyD) has an important impact on the environment and human health. However, there is currently no method for trace detection of PyD. Here, we successfully designed diaminomethylene-4H-pyran (1) as first specific fluorescent probe Only by adding PyD to 1, blue fluorescence at 455 nm, color solution changes from colorless yellow. The limit 1.12 × 10

Язык: Английский

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An azo substituted quinoline‐malononitrile enzyme‐activable aggregation‐induced emission nanoprobe for hypoxia imaging

Smart Molecules, Год журнала: 2024, Номер unknown

Опубликована: Сен. 4, 2024

Abstract The development of efficient aggregation‐induced emission (AIE) active probes is crucial for disease diagnosis, particularly tumors and cardiovascular diseases. Current AIE‐active primarily focus on improving their water solubility to resist aggregation, thereby achieving an initial fluorescence‐off state. However, the complex biological environment can cause undesirable resulting in false signals. To address this issue, we have ingeniously introduced azo group into AIE luminogen (AIEgen), developing a reductase‐activated probe, Azo‐quinoline‐malononitrile (QM)‐PN, imaging hypoxic environments. In promotes intramolecular motion through rapid E / Z isomerization, causing excited state energy dissipate via non‐radiative decay, thus turning off fluorescence. presence reductase, Azo‐QM‐PN reduced cleaved produce hydrophobic AIEgen NH 2 ‐QM‐PN, which subsequently aggregates generates situ signal, with reductase. Encapsulation DSPE‐PEG 2000 results formation nanoprobe NPs, effectively penetrate cell membranes, specifically illuminate tumor cells, monitor fluctuations reductase levels, deeply image multicellular spheroids, demonstrating potential imaging. Additionally, NPs selectively atherosclerotic plaque tissues, showing detecting atherosclerosis. Therefore, study, successfully developed enzyme‐activated probe environments, laying foundation further clinical applications.

Язык: Английский

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