SWCNTs functionalized with gold nanoradiosensitizers as radiosensitizers for enhanced radiotherapy in breast cancer

Results in Chemistry, Год журнала: 2025, Номер unknown, С. 102113 - 102113

Опубликована: Фев. 1, 2025

Язык: Английский

---

Stealth Nanoparticles with a “Self-Consuming” Shell for Long-Term Blood Vessel Imaging

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Фев. 16, 2025

The development of lanthanide-doped upconversion nanoparticle (UCNP)-based imaging with minimal autofluorescence and improved penetration depth is important in medical applications. Exogenous nanocarriers readily adsorb plasma proteins following intravenous administration (<0.5 min), resulting the formation a protein corona on fixed surface. facilitates UCNP interception by immune system, preventing targeted delivery to disease sites. In this study, we report novel surface-camouflaging strategy using lanthanide hydroxyl carbonate that slowly dissolved physiological phosphate serum. "self-consuming" inorganic-shell-modified UCNPs (denoted as UCSP-PEG) effectively reduce adhesion more than 90% through dissociation effect associated amphiphilic poly(ethylene glycol) (PEG)-modified determined an ex vivo assay. UCSP-PEG exhibits prolonged blood circulation time (t1/2 = 73.9 ± 9.5 185 times camouflage materials without "stealth" feature, can employ upconverted luminescence (UCL) monitor tumor-related vessels for at least 120 min. Based superior optical properties UCSP-PEG, application UCL dual-channel stereoscope magnification system has enabled observation capillaries high resolution, offering powerful tool monitoring biological activities fine tissue level. This work provides nanovehicle, resisting based significantly advance target-specific cancer diagnosis.

Язык: Английский

---

Chalcogen Modification: One-Step Strategy for Tuning the Photophysical Properties and NIR Phototherapy of Iodinated BODIPY

Materials Chemistry Frontiers, Год журнала: 2024, Номер 8(20), С. 3308 - 3320

Опубликована: Янв. 1, 2024

A schematic illustration of iodinated BODIPY based on chalcogen modification the photophysical properties for near-infrared phototherapy tumors.

Язык: Английский

---

CrO3-doped P2O5-KF-Al2O3 glasses for NIR light-emitting devices: Crystalline field evaluation via Tanabe-Sugano diagram and investigation of the nephelauxetic effect

Journal of Molecular Structure, Год журнала: 2025, Номер unknown, С. 141616 - 141616

Опубликована: Янв. 1, 2025

Язык: Английский

---

Biodegradable Persistent Luminescence Nanoparticles as Pyroptosis Inducer for High‐Efficiency Tumor Immunotherapy

Advanced Science, Год журнала: 2024, Номер 11(39)

Опубликована: Авг. 19, 2024

Abstract Pyroptosis possesses potent antitumor immune activity, making pyroptosis inducer development a promising direction for tumor immunotherapy. Persistent luminescence nanoparticles (PLNPs) are highly sensitive optical probes extensively employed in diagnosis and therapy. However, based on PLNPs has not been reported yet. Herein, polyethylene glycol–poly lactic acid‐co‐glycolic acid (PEG–PLGA: PP) modified biodegradable CaS:Eu 2+ (CSE@PP) synthesized as immunotherapy the first time. The CSE@PP biowindow persistent (PersL) pH‐responsive degradation properties, allowing it to remain stable under neutral pH but degrade when exposed weak (pH < 6.5). During within tumor, constantly releases H 2 S Ca while its PersL gradually fades away. Thus, signal can self‐monitor release. Furthermore, released result mitochondrial dysfunction inactivation of reactive oxygen species scavenging enzymes, synergistic facilitating intracellular oxidative stress, which induces caspase‐1/GSDM‐D dependent subsequent responses. In word, is confirmed that release pyroptosis‐mediated Immunotherapy. This work will facilitate biomedical applications inspire pyroptosis‐induced

Язык: Английский

---

Instant in situ highlighting of latent fingerprints by a green fluorescent probe based on aggregation-induced emission

Biosensors and Bioelectronics, Год журнала: 2024, Номер 263, С. 116572 - 116572

Опубликована: Июль 14, 2024

Язык: Английский

---

The Impact of Graphene Oxide Nanoparticles Decorated with Silver Nanoparticles (GrO/AgNP) on the Cellulose Acetate (CA) Membrane Matrix Used for Hydrocarbon Removal from Water

Membranes, Год журнала: 2025, Номер 15(6), С. 158 - 158

Опубликована: Май 23, 2025

Adding nanomaterials to polymer membranes can improve certain properties, such as the photocatalytic degradation of contaminants and antibacterial qualities. However, interaction between polymers is often limited by presence functional groups that trap nanostructures within matrix. This study focuses on synthesis silver-decorated graphene oxide nanoparticles their integration into cellulose acetate membranes. Characterization was conducted using various techniques, including electron microscopy (SEM), thermogravimetric analysis, FTIR, goniometry, filterability tests. The results indicate CA with decorated exhibit improved thermal stability, making them more effective for removing heavy hydrocarbons without risk nanomaterial elution during temperature fluctuations in contaminated water flow subjected filtration. Furthermore, these structures enhance hydrophobicity due interactions oxygenated GrO silver ions. While additional networks may reduce permeate rate, they significantly increase efficiency contaminant removal.

Язык: Английский

---

Lanthanide Coordinated Multicolor Luminescent Polymeric Hydrogels

Journal of Materials Chemistry C, Год журнала: 2024, Номер 12(45), С. 18201 - 18210

Опубликована: Янв. 1, 2024

A review of lanthanide coordinated multicolor luminescent polymeric hydrogels (LPHs) based on the synthetic strategies.

Язык: Английский

---

Dimeric PD-L1 specific affibody grafted Fe-based nanosheets for tumor-targeting dual-mode magnet resonance imaging and enhancement of Photothermal-Immunotherapy

Chemical Engineering Journal, Год журнала: 2025, Номер 505, С. 159400 - 159400

Опубликована: Янв. 9, 2025

Язык: Английский

---

BDT mediated asymmetric deposition of Ag on gold nanobipyramids for SERS detection of drug residues in aquaculture water

Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2025, Номер 713, С. 136558 - 136558

Опубликована: Март 3, 2025

Язык: Английский

---