A facile, environmentally-benign, green and a novel synthesis of tert-butyl-quinolines by using Fe3O4-MWCNT@CeO2 as recyclable catalyst
Inorganic Chemistry Communications,
Год журнала:
2024,
Номер
162, С. 112280 - 112280
Опубликована: Март 9, 2024
Язык: Английский
Green synthesis of novel pyrano[2,3-c]pyrazole-5-carbonitrile analogues by using Fe5(PW10V2O40)3 nanocatalyst through a one-pot Knoevenagel condensation and Michael addition mechanism
Inorganic Chemistry Communications,
Год журнала:
2023,
Номер
159, С. 111906 - 111906
Опубликована: Дек. 12, 2023
Язык: Английский
Synthesis, activity, docking and dynamic simulation studies of novel pyrazolo-pyrano[2,3-d]-pyrimidine analogues as anti-diabetic agents
Journal of Molecular Structure,
Год журнала:
2024,
Номер
1305, С. 137720 - 137720
Опубликована: Фев. 7, 2024
Язык: Английский
A simple, safe, eco‐friendly, and unique synthesis of hexahydro‐quinolines employing Fe3O4‐MWCNT@MnO2 as a reusable catalyst
Applied Organometallic Chemistry,
Год журнала:
2024,
Номер
38(8)
Опубликована: Май 30, 2024
This
work
aims
to
explore
the
catalytic
potential
of
manganese
oxide
(MnO
2
)
supported
on
(Fe
3
O
4
‐MWCNT)
nano‐composite,
which
is
composed
iron
and
multi‐walled
carbon
nanotubes.
The
nano‐composite
was
synthesized
using
a
simple
impregnation
technique.
catalyst
material
extensively
characterized
variety
possible
analytical
methods,
including
X‐ray
diffraction
(XRD),
Brunauer–Emmett–Teller
(BET),
thermogravimetric
analysis
(TGA),
scanning
electron
microscopy
(SEM),
transmission
(TEM),
energy
dispersive
spectroscopy
(EDS).
Then,
utilizing
multi‐component
condensation
protocol
comprising
substituted
aldehydes,
cyclohexadione,
ethylacetoacetate,
NH
OAc,
efficacy
Fe
‐MWCNT@MnO
assessed
for
synthesizing
novel
hexahydro‐quinoline
analogues.
found
be
effective
because
its
huge
specific
surface
area,
stability,
porosity,
distinctive
exposed
surfaces.
catalyst's
exhibited
an
exceptionally
active
nature,
as
seen
by
notably
high
turnover
frequency.
Herein,
we
present
reusable
method
that
produces
outstanding
product
yields
(93%–97%)
under
mild
reaction
conditions,
ethanol
green
solvent.
Cost‐effectiveness,
environmental
safety,
atom
efficiency
are
achieved
nano‐composite.
Язык: Английский
Ultrasound-Assisted Synthesis and Characterization of 5-Carbonitrile-Functionalized tetrahydropyrimidine Derivatives with Evaluation of Their Antimicrobial Activity
Oriental Journal Of Chemistry,
Год журнала:
2024,
Номер
40(1), С. 281 - 287
Опубликована: Фев. 24, 2024
The
green
synthesis
approach
employs
ultrasound
waves
as
an
effective
and
environmentally
friendly
strategy
to
catalyze
chemical
reactions.
Within
this
framework,
carbonitrile-bearing
tetrahydropyrimidine
derivatives
were
successfully
synthesized.
This
involved
the
reaction
of
malononitrile,
urea
or
thiourea,
variously
substituted
aldehydes
in
presence
morpholine
a
catalyst,
conducted
aqueous
conditions
under
ultrasonic
irradiation.
Notably,
method
resulted
elevated
yields
significantly
reduced
times
when
compared
conventional
approaches.
synthesized
compounds
underwent
comprehensive
characterization
using
various
spectroscopic
techniques,
including
UV-Vis,
1H
NMR,
13C
mass
spectrometry.
innovative
process
aligns
with
principles
chemistry,
emphasizing
efficiency,
sustainability,
reduction
environmental
impact
synthesis.
Язык: Английский
Design, synthesis, biological evolution and in silico studies of a novel 1,2,3,4‐tetrazole fused with 1,3,4‐thiadiazole‐2‐amine derivatives
Muthirevula Rajeswari,
Begari Nagaraju,
Shaik Yasmintaj
и другие.
Journal of Heterocyclic Chemistry,
Год журнала:
2024,
Номер
61(7), С. 1116 - 1124
Опубликована: Май 17, 2024
Abstract
A
new
series
of
tetrazole
fused
with
1,3,4‐thiadiazole‐2‐amine
(
4a–j
)
moiety
have
been
synthesized.
thorough
characterization
each
compound
was
carried
out
using
mass
spectrum
data,
FT‐IR,
1
H,
and
13
C
NMR
studies.
The
antibacterial
effectiveness
these
prepared
substances
assessed
in
vitro
against
Gram‐(−)
strains
P.
aeruginosa
E.
coli
,
as
well
Gram‐(+)
B.
subtilis
S.
aureus
.
Molecules
4f
4h
showed
exceptional
both
types
when
compared
to
the
reference
antibiotic
Streptomycin.
Moreover
evolution
molecular
docking
silico
studies
also
helpful
for
all
synthesized
compounds
amoxicillin.
investigation
included
a
look
at
protein
stability,
APO‐protein
dynamics,
interactions.
Using
Molecular
Dynamics
(MD)
simulations
Desmond
Maestro
version
11.3
this
inquiry,
potential
lead
molecule
found.
Язык: Английский
A green and eco-efficient protocol for the synthesis of benzo-[7]-annulene-1,3-dicarbonitriles by using simple mortar pestle grinding
Cleaner Engineering and Technology,
Год журнала:
2024,
Номер
21, С. 100762 - 100762
Опубликована: Май 31, 2024
The
synthesis
of
novel
benzo-[7]-annulene-1,3-dicarbonitrile
analogues
has
been
accomplished
using
an
environmentally
friendly
and
green
protocol.
This
mortar
pestle
grinding
method
that
is
both
ethically
responsible
commercially
practical.
By
producing
the
necessary
with
good
results
(89%-97%)
in
a
short
reaction
time
(≤
30
minutes),
this
approach
successfully
indicates
even
aldehydes
severe
steric
hindrance
play
active
part
process.
faster
work-up
processes,
reduction
operating
difficulties,
increased
yields
are
notable
among
its
advantages
over
earlier
systems.
strategy
uses
method,
which
well
known
for
following
guidelines
economically
sensible
friendly.
It
important
to
note
offers
considerable
advancement
approaches
were
characterized
by
drawn-out
procedures,
operational
complexity,
low
yields.
Язык: Английский