Опубликована: Ноя. 15, 2024
Язык: Английский
Опубликована: Ноя. 15, 2024
Язык: Английский
Chemical Engineering Journal, Год журнала: 2024, Номер 501, С. 157673 - 157673
Опубликована: Ноя. 14, 2024
Язык: Английский
Процитировано
2Materials & Design, Год журнала: 2024, Номер 246, С. 113286 - 113286
Опубликована: Сен. 7, 2024
Язык: Английский
Процитировано
1Advanced Science, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 8, 2024
Electrical stimulation has been hotpot research and provoked extensive interest in a broad application such as wound closure, tissue injury repair, nerve engineering. In particular, immense efforts have dedicated to developing electrical microneedles, which demonstrate unique features terms of controllable drug release, real-time monitoring, therapy, thus greatly accelerating the process healing. Here, review state-of-art concerning microneedles applied for treatment is presented. After comprehensive analysis mechanisms on healing, derived three types are clarified summarized. Further, their applications healing highlighted. Finally, current perspectives directions development future improving addressed.
Язык: Английский
Процитировано
1Biomaterials Science, Год журнала: 2024, Номер unknown
Опубликована: Янв. 1, 2024
Microneedle patches have emerged as a promising approach for diabetic wound healing by enabling the targeted delivery of therapeutic agents such stem cells and their derived exosomes, well localized bioactive moieties. These offer non-invasive efficient method administering payloads directly to site wound, bypassing systemic circulation minimizing potential side effects. The holds immense promoting tissue regeneration accelerating in patients. Similarly, cell-derived which are known regenerative anti-inflammatory properties, can enhance process. Furthermore, microneedle enable precise controlled release moieties, growth factors cytokines, site, creating conducive microenvironment repair regeneration. challenges associated with multifaceted. Biocompatibility issues, variability skin characteristics among patients, regulatory hurdles, scalability, cost considerations, long-term stability, patient acceptance compliance all present significant barriers widespread adoption optimization technology clinical practice. Overcoming these will require collaborative efforts from various stakeholders advance field address critical gaps research development. Ongoing focuses on enhancing biocompatibility mechanical properties materials, developing customizable technologies personalized treatment approaches, integrating advanced functionalities sensors real-time monitoring, improving engagement adherence through education support mechanisms. advancements improve management providing tailored therapies that promote faster reduce complications. This review explores current landscape context management, highlighting both need be addressed future perspectives this innovative modality.
Язык: Английский
Процитировано
1Matter, Год журнала: 2024, Номер 7(8), С. 2663 - 2664
Опубликована: Авг. 1, 2024
Язык: Английский
Процитировано
0Biomaterials Advances, Год журнала: 2024, Номер 168, С. 214124 - 214124
Опубликована: Ноя. 26, 2024
Язык: Английский
Процитировано
0International Journal of Biological Macromolecules, Год журнала: 2024, Номер 291, С. 139126 - 139126
Опубликована: Дек. 24, 2024
Язык: Английский
Процитировано
0Опубликована: Ноя. 15, 2024
Язык: Английский
Процитировано
0