Chinese Chemical Letters, Год журнала: 2024, Номер unknown, С. 110767 - 110767
Опубликована: Дек. 1, 2024
Язык: Английский
Journal of Colloid and Interface Science, Год журнала: 2024, Номер 675, С. 1040 - 1051
Опубликована: Июль 11, 2024
Язык: Английский
Процитировано
10
Carbohydrate Polymers, Год журнала: 2024, Номер 348, С. 122806 - 122806
Опубликована: Сен. 27, 2024
Язык: Английский
Процитировано
8
Chemical Engineering Journal, Год журнала: 2024, Номер 497, С. 154521 - 154521
Опубликована: Авг. 3, 2024
Язык: Английский
Процитировано
7
Chemical Engineering Journal, Год журнала: 2024, Номер 495, С. 153095 - 153095
Опубликована: Июнь 13, 2024
Язык: Английский
Процитировано
6
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 279, С. 135519 - 135519
Опубликована: Сен. 10, 2024
Язык: Английский
Процитировано
6
Advances in Colloid and Interface Science, Год журнала: 2024, Номер 334, С. 103306 - 103306
Опубликована: Окт. 5, 2024
Chronic wounds are a critical and costly complication that affects millions of patients each year, especially suffering from diabetes, constitute serious global healthcare problem needs immediate attention. In this direction, novel dressings can integrate appropriate physicochemical biological features, mechanical durability, the capacity for therapy great clinical importance. For instance, self-healable hydrogels, with antibacterial activity high tissue adhesion, have attracted increasing attention wound management applications. Despite their potential, existing hydrogel networks exhibit limitations in strength regeneration, efficacy, scalability, indicating need further improvement field. This review focuses on exactly these recent advances field special focus self-healing adhesive hydrogel-based as well structures, construction strategies, adhesion mechanisms, emerging usage healing By shedding light developments, we aim to contribute ongoing pursuit enhanced solutions chronic care.
Язык: Английский
Процитировано
6
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 277, С. 134565 - 134565
Опубликована: Авг. 6, 2024
Chronic wounds represent a serious worldwide concern, being often associated with bacterial infections. As the prevalence of infections increase, it is crucial to search for alternatives. Essential oils (EOs) constitute promising option antibiotics due their strong anti-inflammatory, analgesic, antioxidant and antibacterial properties. However, such compounds present high volatility. To address this issue, drug delivery system composed coaxial wet-spun fibers was engineered different EOs, namely clove oil (CO), cinnamon leaf (CLO) tea tree (TTO), were loaded. Briefly, two syringe pumps, coagulation bath deionized water, cylindrical-shaped collector spinneret used. A 10 % w/v polycaprolactone (PCL) solution combined EOs at 2 × minimum bactericidal concentration (MBC) loaded connected inner port, whereas cellulose acetate (CA) mixed polyethylene glycol (PEG) ratio 90:10 v/v (to increase fibers' elasticity) outer port. This layer used as barrier pace release entrapped EO. The CA's inherent porosity in water baths allowed access fiber's core. CA also (CA:PEG), elasticity. Microfibers maintained structural integrity during 28 days incubation physiological-like environments. They showed elasticities (maximum elongations break >300 %) resistance rupture mechanical assessments, reaching mass losses only ≈ 2.29 - 57.19 %. released from prolonged sustained fashion, which 30 EO 24 h media, demonstrating great effectiveness against Staphylococcus aureus, epidermidis, Escherichia coli Pseudomonas aeruginosa, most prevalent bacteria chronic wounds. Moreover, microfibers effective effects, presenting up 59 reduction 2,2-diphenyl-1-picrylhydrazyl (DPPH) activity. Furthermore, deemed safe contact fibroblasts human keratinocytes, metabolic activities higher than 80 after 48 incubation. Data confirmed suitability potential therapeutics
Язык: Английский
Процитировано
4
Journal of Biomaterials Science Polymer Edition, Год журнала: 2024, Номер 35(17), С. 2640 - 2659
Опубликована: Авг. 7, 2024
The skin is at risk for injury to external factors since it serves as the body's first line of defense against environment. Hydrogels have drawn much interest due their intrinsic extracellular matrix (ECM) properties and biomimetic, structural, durable mechanical characteristics. enormous potential use in wound healing ability deliver bioactive substances easily. In this study, composite hydrogels were developed by blending guar gum (GG), polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC) with crosslinker TEOS treatment. surface morphology, roughness, stability features characterized several techniques, such FTIR, SEM-EDX, AFM, DSC. increasing ZiF-8 causes more decreased swelling different media (Aqueous > PBS NaCl). amount less hydrophilic behavior biodegradation gel fraction. cytocompatibility Zinc imidazolate framework-8 (ZiF-8) based composites was evaluated fibroblast cell lines viability, proliferation, morphology. caused viability proliferation proper Hence, results show that synthesized may be a candidate numerous repair applications.
Язык: Английский
Процитировано
4
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136965 - 136965
Опубликована: Окт. 30, 2024
Язык: Английский
Процитировано
4
Next Nanotechnology, Год журнала: 2025, Номер 7, С. 100139 - 100139
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0